PGC-1α regulates alanine metabolism in muscle cells

Deletion of the transcriptional coactivator PGC1α in skeletal muscles is associated with reduced expression of genes related to oxidative muscle function

(2016) Yukino Hatazawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatic ALT isoenzymes are elevated in gluconeogenic conditions including diabetes and suppressed by insulin at the protein level

(2015) Kun Qian et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

A muscle-liver-fat signalling axis is essential for central control of adaptive adipose remodelling

(2015) Noriaki Shimizu et al.   Nature Communications

Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α

(2015) Yukino Hatazawa et al.   PLoS One

FOXO1 activates glutamine synthetase gene in mouse skeletal muscles through a region downstream of 3′-UTR: possible contribution to ammonia detoxification

(2014) Yasutomi Kamei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PGC-1α-Mediated Branched-Chain Amino Acid Metabolism in the Skeletal Muscle

(2014) Yukino Hatazawa et al.   PLoS One

Klf15 Orchestrates Circadian Nitrogen Homeostasis

(2012) Darwin Jeyaraj et al.   Cell Metabolism

Metabolic Adaptive ALT Isoenzyme Response in Livers of C57/BL6 Mice Treated with Dexamethasone

(2012) William J. Reagan et al.   TOXICOLOGIC PATHOLOGY

Isoform-Specific Increases in Murine Skeletal Muscle Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α (PGC-1α) mRNA in Response to β2-Adrenergic Receptor Activation and Exercise

(2008) Shinji Miura et al.   ENDOCRINOLOGY

PPARα regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes

(2008) Petra Thulin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY