Steady Augmentation of Anti-Osteoarthritic Actions of Rapamycin by Liposome-Encapsulation in Collaboration with Low-Intensity Pulsed Ultrasound

Liposome-encapsulated farnesol accelerated tissue repair in third-degree burns on a rat model

(2019) Yu Chiuan Wu et al.   BURNS

RNA sequencing reveals target genes of temporomandibular joint osteoarthritis in rats after the treatment of low-intensity pulsed ultrasound

(2018) Dong He et al.   GENE

A MMP7-sensitive photoclickable biomimetic hydrogel for MSC encapsulation towards engineering human cartilage

(2018) Elizabeth A. Aisenbrey et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Liposomes: Clinical Applications and Potential for Image-Guided Drug Delivery

(2018) Narottam Lamichhane et al.   MOLECULES

Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis

(2018) Claire Vinatier et al.   Frontiers in Physiology

Drug-fortified liposomes as carriers for sustained release of NSAIDs: The concept and its validation in the animal model for the treatment of arthritis

(2018) Vijay A. Pawar et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Gomisin N Alleviates Ethanol-Induced Liver Injury through Ameliorating Lipid Metabolism and Oxidative Stress

(2018) Arulkumar Nagappan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Referenzwerte blutchemischer Parameter bei Meerschweinchen bestimmt mit dem Vettest® 8008

(2018) H. Rabe   TIERAERZTLICHE PRAXIS AUSGABE KLEINTIERE HEIMTIERE

Inhibition of interleukin-6 function attenuates the central sensitization and pain behavior induced by osteoarthritis

(2017) Yuangui Lin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Rapamycin Maintains the Chondrocytic Phenotype and Interferes with Inflammatory Cytokine Induced Processes

(2017) Andrea De Luna-Preitschopf et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Liposomal Encapsulation for Systemic Delivery of Propranolol via Transdermal Iontophoresis Improves Bone Microarchitecture in Ovariectomized Rats

(2017) Benjamin Teong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine interleukin 6 are related to synovitis and pain in end-stage knee osteoarthritis patients

(2017) Maja R. Radojčić et al.   PAIN

Recapitulation of physiological spatiotemporal signals promotes in vitro formation of phenotypically stable human articular cartilage

(2017) Johnathan J. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic Effect of Rapamycin and Metformin Against Age-Dependent Oxidative Stress in Rat Erythrocytes

(2017) Abhishek Kumar Singh et al.   REJUVENATION RESEARCH

Osteoarthritis: toward a comprehensive understanding of pathological mechanism

(2017) Di Chen et al.   Bone Research

In vitro chondrogenesis of Wharton’s jelly mesenchymal stem cells in hyaluronic acid-based hydrogels

(2016) Ewelina Aleksander-Konert et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

An update on the up and coming therapies to treat osteoarthritis, a multifaceted disease

(2016) Jorge A. Roman-Blas et al.   EXPERT OPINION ON PHARMACOTHERAPY

Improvement and enhancement of antibladder carcinoma cell effects of heteronemin by the nanosized hyaluronan aggregation

(2016) Han Hsiang Huang et al.   International Journal of Nanomedicine

mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation

(2016) Bo Yan et al.   Nature Communications

Osteoarthritis

(2016) Johanne Martel-Pelletier et al.   Nature Reviews Disease Primers

Low-Intensity Pulsed Ultrasound Treatment at an Early Osteoarthritis Stage Protects Rabbit Cartilage From Damage via the Integrin/Focal Adhesion Kinase/Mitogen-Activated Protein Kinase Signaling Pathway

(2015) Peng Xia et al.   JOURNAL OF ULTRASOUND IN MEDICINE

Animal Models of Osteoarthritis

(2015) A. M. McCoy   VETERINARY PATHOLOGY

Effect of low intensity pulsed ultrasound on expression of TIMP-2 in serum and expression of mmp-13 in articular cartilage of rabbits with knee osteoarthritis

(2015) Jing-Bo Ji et al.   Asian Pacific Journal of Tropical Medicine

mTOR: A Potential Therapeutic Target in Osteoarthritis?

(2015) Bandna Pal et al.   Drugs in research & development

Effects of ultrasound on estradiol level, bone mineral density, bone biomechanics and matrix metalloproteinase-13 expression in ovariectomized rabbits

(2015) LU XIA et al.   Experimental and Therapeutic Medicine

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis

(2014) Yue Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Intra-articular administration of gelatin hydrogels incorporating rapamycin–micelles reduces the development of experimental osteoarthritis in a murine model

(2014) Tokio Matsuzaki et al.   BIOMATERIALS

The stimulatory effects of alpha1-adrenergic receptors on TGF-beta1, IGF-1 and hyaluronan production in human skin fibroblasts

(2014) Ming-Huei Liao et al.   CELL AND TISSUE RESEARCH

Longevity, aging and rapamycin

(2014) Dan Ehninger et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Osteoarthritis pain: nociceptive or neuropathic?

(2014) Matthew Thakur et al.   Nature Reviews Rheumatology

Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells

(2014) Debangshu Samanta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis

(2014) Koji Takayama et al.   ARTHRITIS RESEARCH & THERAPY

Rapamycin Inhibits Transforming Growth Factor β1-Induced Fibrogenesis in Primary Human Lung Fibroblasts

(2013) Yu Gao et al.   YONSEI MEDICAL JOURNAL

The Future of Osteoarthritis Therapeutics: Targeted Pharmacological Therapy

(2013) A. Mobasheri   Current Rheumatology Reports

Intra-articular delivery of liposomal celecoxib–hyaluronate combination for the treatment of osteoarthritis in rabbit model

(2012) Ji Dong et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

New findings in osteoarthritis pathogenesis: therapeutic implications

(2012) Lia Pulsatelli et al.   Therapeutic Advances in Chronic Disease

Autophagy activation by rapamycin reduces severity of experimental osteoarthritis

(2011) Beatriz Caramés et al.   ANNALS OF THE RHEUMATIC DISEASES

Autophagy modulates osteoarthritis-related gene expression in human chondrocytes

(2011) Hiroshi Sasaki et al.   ARTHRITIS AND RHEUMATISM

Effect of Low-Intensity Pulsed Ultrasound on MMP-13 and MAPKs Signaling Pathway in Rabbit Knee Osteoarthritis

(2011) Xueping Li et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA

(2011) Martin K. Lotz et al.   Nature Reviews Rheumatology

The Autophagy Connection

(2010) Daniel J. Klionsky   DEVELOPMENTAL CELL

Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells

(2010) Kumiko Tanabe et al.   Journal of Neuroinflammation

Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis

(2010) A. Loyola-Sánchez et al.   OSTEOARTHRITIS AND CARTILAGE

Modification of osteoarthritis in the guinea pig with pulsed low-intensity ultrasound treatment

(2010) I. Gurkan et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the guinea pig

(2010) V.B. Kraus et al.   OSTEOARTHRITIS AND CARTILAGE

Functional α1- and β2-adrenergic receptors in human osteoblasts

(2009) H.H. Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Collagen fibril disruption occurs early in primary guinea pig knee osteoarthritis

(2009) J.L. Huebner et al.   OSTEOARTHRITIS AND CARTILAGE

mTOR signaling contributes to chondrocyte differentiation

(2008) Chanika Phornphutkul et al.   DEVELOPMENTAL DYNAMICS

Effects of Pulsed Low-Intensity Ultrasound on Human Child Chondrocytes

(2008) Yin-Chun Tien et al.   ULTRASOUND IN MEDICINE AND BIOLOGY