Journal
VIRAL IMMUNOLOGY
Volume 30, Issue 2, Pages 82-97Publisher
MARY ANN LIEBERT, INC
DOI: 10.1089/vim.2016.0125
Keywords
MDSCs; viral infections; immunotherapeutic approaches
Categories
Funding
- Public Health Service from the National Institutes of Health [CA-50157, P30 GM10345]
- American Association of Immunologists Careers in Immunology Fellowship Program
- NIH [T32 AI007363]
- National Cancer Institute [CA23108]
- NIH/NCRR NIGMS COBRE [RR16437, GM103415]
Ask authors/readers for more resources
Myeloid-derived suppressor cells (MDSCs) are heterogeneous immature myeloid cells that are well described as potent immune regulatory cells during human cancer and murine tumor models. Reports of MDSCs during viral infections remain limited, and their association with immunomodulation of viral diseases is still being defined. Here, we provide an overview of MDSCs or MDSC-like cells identified during viral infections, including murine viral models and human viral diseases. Understanding the similarities and/or differences of virally induced versus tumor-derived MDSCs will be important for designing future immunotherapeutic approaches.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
