Clinical epigenetics and multidrug-resistant bacterial infections: host remodelling in critical illness

Insights Into Non-coding RNAs as Novel Antimicrobial Drugs

(2019) Gisela Parmeciano Di Noto et al.   Frontiers in Genetics

Serum Exosomal miRNAs Are Associated with Active Pulmonary Tuberculosis

(2019) Shamila D. Alipoor et al.   DISEASE MARKERS

Mechanism of Action for HDAC Inhibitors—Insights from Omics Approaches

(2019) Wenbo Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The path toward using microbial metabolites as therapies

(2019) Hélène C. Descamps et al.   EBioMedicine

Epigenetics Mechanisms in Multiorgan Dysfunction Syndrome

(2019) Ettore Crimi et al.   ANESTHESIA AND ANALGESIA

The diverse roles of DNA methylation in mammalian development and disease

(2019) Maxim V. C. Greenberg et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fluid-based assays and precision medicine of cardiovascular diseases: the ‘hope’ for Pandora’s box?

(2019) Giuditta Benincasa et al.   JOURNAL OF CLINICAL PATHOLOGY

Differential Epigenetic Factors in the Prediction of Cardiovascular Risk in Diabetic Patients

(2019) Claudio Napoli et al.   European Heart Journal-Cardiovascular Pharmacotherapy

Strengths and Opportunities of Network Medicine in Cardiovascular Diseases

(2019) Giuditta Benincasa et al.   CIRCULATION JOURNAL

Donor-derived infections, lessons learnt from the past, and what is the future going to bring us

(2018) Paolo Antonio Grossi   Current Opinion in Organ Transplantation

Exploring the multi-drug resistance in Escherichia coli O157:H7 by gene interaction network: A systems biology approach

(2018) Sravan Kumar Miryala et al.   GENOMICS

Identifying differentially expressed long non-coding RNAs in PBMCs in response to the infection of multidrug-resistant tuberculosis

(2018) Hong Yan et al.   Infection and Drug Resistance

Induction of Trained Innate Immunity in Human Monocytes by Bovine Milk and Milk-Derived Immunoglobulin G

(2018) Marloes van Splunter et al.   Nutrients

Epigenetic modulator UVI5008 inhibits MRSA by interfering with bacterial gyrase

(2018) Gianluigi Franci et al.   Scientific Reports

Epigenetic Hallmarks of Fetal Early Atherosclerotic Lesions in Humans

(2018) Filomena de Nigris et al.   JAMA Cardiology

Clinical relevance of epigenetics in the onset and management of type 2 diabetes mellitus

(2017) Linda Sommese et al.   Epigenetics

The intensive care medicine research agenda on multidrug-resistant bacteria, antibiotics, and stewardship

(2017) Marin H. Kollef et al.   INTENSIVE CARE MEDICINE

Characterization of a novel panel of plasma microRNAs that discriminates between Mycobacterium tuberculosis infection and healthy individuals

(2017) Jia-Yi Cui et al.   PLoS One

BET Bromodomain as a Target of Epigenetic Therapy

(2016) Tomomi Noguchi-Yachide   CHEMICAL & PHARMACEUTICAL BULLETIN

Focus on antimicrobial use in the era of increasing antimicrobial resistance in ICU

(2016) Matteo Bassetti et al.   INTENSIVE CARE MEDICINE

Interpreting phenotypic antibiotic tolerance and persister cells as evolution via epigenetic inheritance

(2016) Troy Day   MOLECULAR ECOLOGY

The therapeutic potential of epigenetic manipulation during infectious diseases

(2016) Joby Cole et al.   PHARMACOLOGY & THERAPEUTICS

Histone deacetylase inhibition enhances antimicrobial peptide but not inflammatory cytokine expression upon bacterial challenge

(2016) Natalie Fischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

Antimicrobial resistance—a threat to the world’s sustainable development

(2016) Dušan Jasovský et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

What’s new in multidrug-resistant pathogens in the ICU?

(2016) Gabor Zilahi et al.   Annals of Intensive Care

A quorum-sensing signal promotes host tolerance training through HDAC1-mediated epigenetic reprogramming

(2016) Arunava Bandyopadhaya et al.   Nature Microbiology

Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection

(2016) Garima Sharma et al.   Scientific Reports

Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages

(2015) Juliana K. Ariffin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Local chromatin microenvironment determines DNMT activity: from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylase

(2015) Monique G P van der Wijst et al.   Epigenetics

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

(2015) Alain Pacis et al.   GENOME RESEARCH

RNA-mediated epigenetic regulation of gene expression

(2015) Daniel Holoch et al.   NATURE REVIEWS GENETICS

Adaptive Resistance in Bacteria Requires Epigenetic Inheritance, Genetic Noise, and Cost of Efflux Pumps

(2015) Santiago Sandoval Motta et al.   PLoS One

Recommendations for screening of donor and recipient prior to solid organ transplantation and to minimize transmission of donor–derived infections

(2014) O. Len et al.   CLINICAL MICROBIOLOGY AND INFECTION

Salmonella enterica Serovar Enteritidis Modulates Intestinal Epithelial miR-128 Levels to Decrease Macrophage Recruitment via Macrophage Colony-Stimulating Factor

(2014) Tianfu Zhang et al.   JOURNAL OF INFECTIOUS DISEASES

Molecular mechanisms of antibiotic resistance

(2014) Jessica M. A. Blair et al.   NATURE REVIEWS MICROBIOLOGY

Aminoglycoside resistance 16S rRNA methyltransferases block endogenous methylation, affect translation efficiency and fitness of the host

(2014) V. S. Lioy et al.   RNA

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

(2014) E. Seto et al.   Cold Spring Harbor Perspectives in Biology

Differentially Expressed Epigenome Modifiers, Including Aurora Kinases A and B, in Immune Cells in Rheumatoid Arthritis in Humans and Mouse Models

(2013) Tibor T. Glant et al.   ARTHRITIS AND RHEUMATISM

Latent Enhancers Activated by Stimulation in Differentiated Cells

(2013) Renato Ostuni et al.   CELL

Legionella pneumophila Effector RomA Uniquely Modifies Host Chromatin to Repress Gene Expression and Promote Intracellular Bacterial Replication

(2013) Monica Rolando et al.   Cell Host & Microbe

Microbial Persistence and the Road to Drug Resistance

(2013) Nadia R. Cohen et al.   Cell Host & Microbe

Programmed Heterogeneity: Epigenetic Mechanisms in Bacteria

(2013) Josep Casadesús et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial

(2013) Sung Won Choi et al.   LANCET ONCOLOGY

Epigenetics and Bacterial Infections

(2013) H. Bierne et al.   Cold Spring Harbor Perspectives in Medicine

Altered serum microRNAs as biomarkers for the early diagnosis of pulmonary tuberculosis infection

(2012) Yuhua Qi et al.   BMC INFECTIOUS DISEASES

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Primary Prevention of Atherosclerosis

(2012) Claudio Napoli et al.   CIRCULATION

Histone methylation: a dynamic mark in health, disease and inheritance

(2012) Eric L. Greer et al.   NATURE REVIEWS GENETICS

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

(2012) J. Kleinnijenhuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicobacter pylori infection promotes methylation of WWOX gene in human gastric cancer

(2011) Jiaqin Yan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance

(2011) A.-P. Magiorakos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Creeping baselines and adaptive resistance to antibiotics

(2011) Lucía Fernández et al.   DRUG RESISTANCE UPDATES

The epigenetic landscape and clinical implications

(2011) Stuart A. Kauffman   JOURNAL OF CRITICAL CARE

Uropathogenic E. coli infection provokes epigenetic downregulation of CDKN2A (p16INK4A) in uroepithelial cells

(2011) Cornelia Tolg et al.   LABORATORY INVESTIGATION

H. pylori-induced promoter hypermethylation downregulates USF1 and USF2 transcription factor gene expression

(2010) Françoise I. Bussière et al.   CELLULAR MICROBIOLOGY

Hyperglycemia Induces a Dynamic Cooperativity of Histone Methylase and Demethylase Enzymes Associated With Gene-Activating Epigenetic Marks That Coexist on the Lysine Tail

(2009) D. Brasacchio et al.   DIABETES

International Study of the Prevalence and Outcomes of Infection in Intensive Care Units

(2009) Jean-Louis Vincent   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: Its possible involvement in the formation of epigenetic field defect

(2008) Takayuki Ando et al.   INTERNATIONAL JOURNAL OF CANCER