A quorum-sensing signal promotes host tolerance training through HDAC1-mediated epigenetic reprogramming

Beyond receptors and signaling: epigenetic factors in the regulation of innate immunity

(2015) Stuti Mehta et al.   IMMUNOLOGY AND CELL BIOLOGY

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(2015) Evan S Snitkin et al.   NATURE GENETICS

Innate immune memory: a paradigm shift in understanding host defense

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Innate immune memory: towards a better understanding of host defense mechanisms

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Bacteria Fighting Back: How Pathogens Target and Subvert the Host Innate Immune System

(2014) L. Evan Reddick et al.   MOLECULAR CELL

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Tissue damage control in disease tolerance

(2014) Miguel P. Soares et al.   TRENDS IN IMMUNOLOGY

Cell plasticity in wound healing: paracrine factors of M1/ M2 polarized macrophages influence the phenotypical state of dermal fibroblasts

(2013) Diana TA Ploeger et al.   Cell Communication and Signaling

Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group

(2013) Mercedes Lobera et al.   Nature Chemical Biology

A Small Volatile Bacterial Molecule Triggers Mitochondrial Dysfunction in Murine Skeletal Muscle

(2013) A. Aria Tzika et al.   PLoS One

A Quorum Sensing Small Volatile Molecule Promotes Antibiotic Tolerance in Bacteria

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HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner

(2013) M. Malvaez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of a histone deacetylase 6 inhibitor and its biological effects

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A Role for SIRT2-Dependent Histone H3K18 Deacetylation in Bacterial Infection

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Epigenetics and Bacterial Infections

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Bacterial Quorum Sensing: Its Role in Virulence and Possibilities for Its Control

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Tolerance of Infections

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Nuclear factor- B binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome

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Disease Tolerance as a Defense Strategy

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The Quorum Sensing Volatile Molecule 2-Amino Acetophenon Modulates Host Immune Responses in a Manner that Promotes Life with Unwanted Guests

(2012) Arunava Bandyopadhaya et al.   PLoS Pathogens

Immunomodulatory and Protective Roles of Quorum-Sensing Signaling MoleculesN-Acyl Homoserine Lactones during Infection of Mice with Aeromonas hydrophila

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A Quorum Sensing Regulated Small Volatile Molecule Reduces Acute Virulence and Promotes Chronic Infection Phenotypes

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Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

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Attenuated Bordetella pertussis Protects against Highly Pathogenic Influenza A Viruses by Dampening the Cytokine Storm

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Epigenetic reprogramming of host genes in viral and microbial pathogenesis

(2010) Konstantinos Paschos et al.   TRENDS IN MICROBIOLOGY

2-Aminoacetophenone as a potential breath biomarker for Pseudomonas aeruginosa in the cystic fibrosis lung

(2010) Amy J Scott-Thomas et al.   BMC Pulmonary Medicine

Histone deacetylases and the immunological network: implications in cancer and inflammation

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Identification and biosynthesis of tropone derivatives and sulfur volatiles produced by bacteria of the marine Roseobacter clade

(2009) Verena Thiel et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Epigenetic Silencing of Host Cell Defense Genes Enhances Intracellular Survival of the Rickettsial Pathogen Anaplasma phagocytophilum

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Histone Modifications and Chromatin Remodeling during Bacterial Infections

(2008) Mélanie Anne Hamon et al.   Cell Host & Microbe

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(2008) Christopher T. Parker et al.   CELLULAR MICROBIOLOGY

A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas

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MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells

(2008) Chie Nishioka et al.   LEUKEMIA RESEARCH

Immune defence, parasite evasion strategies and their relevance for 'macroscopic phenomena' such as virulence

(2008) P. Schmid-Hempel   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

INDUCTION OF ENDOTOXIN TOLERANCE ENHANCES BACTERIAL CLEARANCE AND SURVIVAL IN MURINE POLYMICROBIAL SEPSIS

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Animal Defenses against Infectious Agents: Is Damage Control More Important Than Pathogen Control

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