γ-Aminobutyric acid (GABA) signalling in plants

Exogenous GABA application transiently improves the tolerance to root hypoxia on a sensitive genotype of Prunus rootstock

(2016) Ariel Salvatierra et al.   ENVIRONMENTAL AND EXPERIMENTAL BOTANY

Vacuolar Chloride Fluxes Impact Ion content and Distribution during Early Salinity Stress

(2016) Ulrike Baetz et al.   PLANT PHYSIOLOGY

Gamma-aminobutyric acid depletion affects stomata closure and drought tolerance of Arabidopsis thaliana

(2016) Dereje Worku Mekonnen et al.   PLANT SCIENCE

GABAergic signalling in the immune system

(2015) A. Barragan et al.   Acta Physiologica

Differential metabolic responses of Beauveria bassiana cultured in pupae extracts, root exudates and its interactions with insect and plant

(2015) Feifei Luo et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

The impact of GABA in harpin-elicited biotic stress responses in Nicotiana tabaccum

(2015) Gizem Dimlioğlu et al.   JOURNAL OF PLANT PHYSIOLOGY

Wheat roots efflux a diverse array of organic N compounds and are highly proficient at their recapture

(2015) Charles R. Warren   PLANT AND SOIL

A tonoplast Glu/Asp/GABA exchanger that affects tomato fruit amino acid composition

(2015) Christopher J. Snowden et al.   PLANT JOURNAL

Metabolite Responses to Exogenous Application of Nitrogen, Cytokinin, and Ethylene Inhibitors in Relation to Heat-Induced Senescence in Creeping Bentgrass

(2015) David Jespersen et al.   PLoS One

Development and regulation of chloride homeostasis in the central nervous system

(2015) Miho Watanabe et al.   Frontiers in Cellular Neuroscience

GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters

(2015) Sunita A. Ramesh et al.   Nature Communications

Closing the loop on the GABA shunt in plants: are GABA metabolism and signaling entwined?

(2015) Simon Michaeli et al.   Frontiers in Plant Science

Insect Herbivory-Elicited GABA Accumulation in Plants is a Wound-Induced, Direct, Systemic, and Jasmonate-Independent Defense Response

(2015) Sandra S. Scholz et al.   Frontiers in Plant Science

The transporter GAT1 plays an important role in GABA-mediated carbon-nitrogen interactions in Arabidopsis

(2015) Albert Batushansky et al.   Frontiers in Plant Science

Dynamics of long-distance signaling via plant vascular tissues

(2015) Michitaka Notaguchi et al.   Frontiers in Plant Science

Ethylene negatively regulates aluminium-induced malate efflux from wheat roots and tobacco cells transformed with TaALMT1

(2014) Qiuying Tian et al.   JOURNAL OF EXPERIMENTAL BOTANY

Exogenous γ-aminobutyric acid (GABA) affects pollen tube growth via modulating putative Ca2+-permeable membrane channels and is coupled to negative regulation on glutamate decarboxylase

(2014) Guang-Hui Yu et al.   JOURNAL OF EXPERIMENTAL BOTANY

 1F64 Residue at GABAA Receptor Binding Site Is Involved in Gating by Influencing the Receptor Flipping Transitions

(2014) M. Szczot et al.   JOURNAL OF NEUROSCIENCE

Mutation of the Arabidopsis Calmodulin-Like Protein CML37 Deregulates the Jasmonate Pathway and Enhances Susceptibility to Herbivory

(2014) Sandra S. Scholz et al.   Molecular Plant

Combined Transcriptomics and Metabolomics of Arabidopsis thaliana Seedlings Exposed to Exogenous GABA Suggest Its Role in Plants Is Predominantly Metabolic

(2014) Albert Batushansky et al.   Molecular Plant

Crystal structure of a human GABAA receptor

(2014) Paul S. Miller et al.   NATURE

Ultraviolet-B radiation modifies the quantitative and qualitative profile of flavonoids and amino acids in grape berries

(2014) J. Martínez-Lüscher et al.   PHYTOCHEMISTRY

Virus-induced gene silencing reveals control of reactive oxygen species accumulation and salt tolerance in tomato byγ-aminobutyric acid metabolic pathway

(2014) HEXIGEDULENG BAO et al.   PLANT CELL AND ENVIRONMENT

Transcriptional Evidence for Inferred Pattern of Pollen Tube-Stigma Metabolic Coupling during Pollination

(2014) Xun Yue et al.   PLoS One

Effect of salt on the growth and metabolism of Glycine max

(2013) Helena Müller Queiroz et al.   BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

γ-Aminobutyric Acid (GABA) Imparts Partial Protection from Heat Stress Injury to Rice Seedlings by Improving Leaf Turgor and Upregulating Osmoprotectants and Antioxidants

(2013) Harsh Nayyar et al.   JOURNAL OF PLANT GROWTH REGULATION

C-Terminus-Mediated Voltage Gating of Arabidopsis Guard Cell Anion Channel QUAC1

(2013) Patrick Mumm et al.   Molecular Plant

Concurrent overactivation of the cytosolic glutamine synthetase and the GABA shunt in the ABA-deficientsitiensmutant of tomato leads to resistance againstBotrytis cinerea

(2013) Hamed Soren Seifi et al.   NEW PHYTOLOGIST

Involvement of the ABCG37 transporter in secretion of scopoletin and derivatives byArabidopsisroots in response to iron deficiency

(2013) Pierre Fourcroy et al.   NEW PHYTOLOGIST

Genetic manipulation of the γ-aminobutyric acid (GABA) shunt in rice: overexpression of truncated glutamate decarboxylase (GAD2) and knockdown of γ-aminobutyric acid transaminase (GABA-T) lead to sustained and high levels of GABA accumulation in rice kern

(2013) Yasuka Shimajiri et al.   PLANT BIOTECHNOLOGY JOURNAL

Pollen Tube Growth Regulation by Free Anions Depends on the Interaction between the Anion Channel SLAH3 and Calcium-Dependent Protein Kinases CPK2 and CPK20

(2013) T. Gutermuth et al.   PLANT CELL

Identification of a Probable Pore-Forming Domain in the Multimeric Vacuolar Anion Channel AtALMT9

(2013) J. Zhang et al.   PLANT PHYSIOLOGY

γ-Aminobutyric acid (GABA) homeostasis regulates pollen germination and polarized growth in Picea wilsonii

(2013) Yu Ling et al.   PLANTA

The vacuolar channel VvALMT9 mediates malate and tartrate accumulation in berries of Vitis vinifera

(2013) Alexis De Angeli et al.   PLANTA

AtALMT9 is a malate-activated vacuolar chloride channel required for stomatal opening in Arabidopsis

(2013) Alexis De Angeli et al.   Nature Communications

Does long-distance GABA signaling via the phloem really occur?

(2012) Barry J. Shelp   Botany

Strategies and tools for studying the metabolism and function of γ-aminobutyrate in plants. II. Integrated analysis

(2012) Barry J. Shelp et al.   Botany

Three-Dimensional Structures of Membrane Proteins from Genomic Sequencing

(2012) Thomas A. Hopf et al.   CELL

Accumulation of γ-aminobutyric acid in germinated soybean (Glycine max L.) in relation to glutamate decarboxylase and diamine oxidase activity induced by additives under hypoxia

(2012) Yuanxin Guo et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

MeJA induces chilling tolerance in loquat fruit by regulating proline and γ-aminobutyric acid contents

(2012) Shifeng Cao et al.   FOOD CHEMISTRY

Hypoxia induces H2O2 production and activates antioxidant defence system in grapevine buds through mediation of H2O2 and ethylene

(2012) R. Vergara et al.   JOURNAL OF EXPERIMENTAL BOTANY

Multiple tyrosine residues at the GABA binding pocket influence surface expression and mediate kinetics of the GABAAreceptor

(2012) Kurt T. Laha et al.   JOURNAL OF NEUROCHEMISTRY

A Fluorescent Sensor for GABA and Synthetic GABAB Receptor Ligands

(2012) Anastasiya Masharina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for selective GABA binding in bacterial pathogens

(2012) Sara Planamente et al.   MOLECULAR MICROBIOLOGY

Protein structure prediction from sequence variation

(2012) Debora S Marks et al.   NATURE BIOTECHNOLOGY

Ion Channels in Plants

(2012) Rainer Hedrich   PHYSIOLOGICAL REVIEWS

γ-Aminobutyric acid transaminase deficiency impairs central carbon metabolism and leads to cell wall defects during salt stress inArabidopsisroots

(2012) HUGUES RENAULT et al.   PLANT CELL AND ENVIRONMENT

Hypothesis/review: Contribution of putrescine to 4-aminobutyrate (GABA) production in response to abiotic stress

(2012) Barry J. Shelp et al.   PLANT SCIENCE

Gamma-amino butyric acid, glutamate dehydrogenase and glutamate decarboxylase levels in phylogenetically divergent plants

(2012) Yolcu Seher et al.   PLANT SYSTEMATICS AND EVOLUTION

Root Secreted Metabolites and Proteins Are Involved in the Early Events of Plant-Plant Recognition Prior to Competition

(2012) Dayakar V. Badri et al.   PLoS One

Compartmentation of GABA metabolism raises intriguing questions

(2012) Barry J. Shelp et al.   TRENDS IN PLANT SCIENCE

The genome of the polar eukaryotic microalga Coccomyxa subellipsoidea reveals traits of cold adaptation

(2012) Guillaume Blanc et al.   GENOME BIOLOGY

Anion Channels/Transporters in Plants: From Molecular Bases to Regulatory Networks

(2011) Hélène Barbier-Brygoo et al.   Annual Review of Plant Biology

Anion channels in plant cells

(2011) Hannes Kollist et al.   FEBS Journal

Factors Influencing Diamine Oxidase Activity and γ-Aminobutyric Acid Content of Fava Bean (Vicia fabaL.) during Germination

(2011) Runqiang Yang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Accumulation Mechanism of γ-Aminobutyric Acid in Tomatoes (Solanum lycopersicum L.) under Low O2 with and without CO2

(2011) Nobukazu Mae et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Elevated cytokinin content in ipt transgenic creeping bentgrass promotes drought tolerance through regulating metabolite accumulation

(2011) E. B. Merewitz et al.   JOURNAL OF EXPERIMENTAL BOTANY

Contribution of Gamma amino butyric acid (GABA) to salt stress responses of Nicotiana sylvestris CMSII mutant and wild type plants

(2011) Neşe Akçay et al.   JOURNAL OF PLANT PHYSIOLOGY

Dynamic Metabonomic Responses of Tobacco(Nicotiana tabacum)Plants to Salt Stress

(2011) Jingtao Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Succinic Semialdehyde Dehydrogenase is Involved in the Robust Patterning of Arabidopsis Leaves along the Adaxial–Abaxial Axis

(2011) Koichi Toyokura et al.   PLANT AND CELL PHYSIOLOGY

GABA Accumulation Causes Cell Elongation Defects and a Decrease in Expression of Genes Encoding Secreted and Cell Wall-Related Proteins in Arabidopsis thaliana

(2011) Hugues Renault et al.   PLANT AND CELL PHYSIOLOGY

Implications of paraquat and hydrogen peroxide-induced oxidative stress treatments on the GABA shunt pathway in Arabidopsis thaliana calmodulin mutants

(2011) Nisreen A. AL-Quraan et al.   Plant Biotechnology Reports

A mitochondrial GABA permease connects the GABA shunt and the TCA cycle, and is essential for normal carbon metabolism

(2011) Simon Michaeli et al.   PLANT JOURNAL

Malate transport by the vacuolar AtALMT6 channel in guard cells is subject to multiple regulation

(2011) Stefan Meyer et al.   PLANT JOURNAL

The Cytosolic Kinases STY8, STY17, and STY46 Are Involved in Chloroplast Differentiation in Arabidopsis

(2011) Giorgia Lamberti et al.   PLANT PHYSIOLOGY

Protein 3D Structure Computed from Evolutionary Sequence Variation

(2011) Debora S. Marks et al.   PLoS One

Glutamate Receptor-Like Genes Form Ca2+ Channels in Pollen Tubes and Are Regulated by Pistil D-Serine

(2011) E. Michard et al.   SCIENCE

The Arabidopsis pop2-1 mutant reveals the involvement of GABA transaminase in salt stress tolerance

(2010) Hugues Renault et al.   BMC PLANT BIOLOGY

A Conserved Mechanism of GABA Binding and Antagonism Is Revealed by Structure-Function Analysis of the Periplasmic Binding Protein Atu2422 inAgrobacterium tumefaciens

(2010) Sara Planamente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The identification of aluminium-resistance genes provides opportunities for enhancing crop production on acid soils

(2010) P. R. Ryan et al.   JOURNAL OF EXPERIMENTAL BOTANY

GABAA receptor antagonism in the ventrocaudal periaqueductal gray increases anxiety in the anxiety-resistant postpartum rat

(2010) Stephanie M. Miller et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Metabolic Alterations in Organic Acids and γ-Aminobutyric Acid in Developing Tomato (Solanum lycopersicum L.) Fruits

(2010) Yong-Gen Yin et al.   PLANT AND CELL PHYSIOLOGY

Phloem-derived γ-aminobutyric acid (GABA) is involved in upregulating nodule N2 fixation efficiency in the model legume Medicago truncatula

(2010) SAAD SULIEMAN et al.   PLANT CELL AND ENVIRONMENT

Mutations in γ-aminobutyric acid (GABA) transaminase genes in plants or Pseudomonas syringae reduce bacterial virulence

(2010) Duck Hwan Park et al.   PLANT JOURNAL

AtALMT12 represents an R-type anion channel required for stomatal movement in Arabidopsis guard cells

(2010) Stefan Meyer et al.   PLANT JOURNAL

Nitrate uptake and utilization is modulated by exogenous γ-aminobutyric acid in Arabidopsis thaliana seedlings

(2010) Jose M. Barbosa et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Interaction with Diurnal and Circadian Regulation Results in Dynamic Metabolic and Transcriptional Changes during Cold Acclimation in Arabidopsis

(2010) Carmen Espinoza et al.   PLoS One

γ-Aminobutyric acid (GABA) metabolism in CO2 treated tomatoes

(2010) Rujira Deewatthanawong et al.   POSTHARVEST BIOLOGY AND TECHNOLOGY

Cytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapy

(2010) R R Ruela-de-Sousa et al.   Cell Death & Disease

R-type anion channel activation is an essential step for ROS-dependent innate immune response inArabidopsissuspension cells

(2009) Jean Colcombet et al.   FUNCTIONAL PLANT BIOLOGY

Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis γ-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate

(2009) Shawn M. Clark et al.   JOURNAL OF EXPERIMENTAL BOTANY

Metabolic responses to salt stress of barley (Hordeum vulgare L.) cultivars, Sahara and Clipper, which differ in salinity tolerance

(2009) Widodo et al.   JOURNAL OF EXPERIMENTAL BOTANY

(+)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate

(2009) Sandra Fonseca et al.   Nature Chemical Biology

Effects of exogenous GABA on gene expression ofCaragana intermediaroots under NaCl stress: regulatory roles for H2O2and ethylene production

(2009) SHENG-QING SHI et al.   PLANT CELL AND ENVIRONMENT

Comparative effects of drought, salt, heavy metal and heat stresses on gamma-aminobutryric acid levels of sesame (Sesamum indicum L.)

(2008) Melike Bor et al.   ACTA PHYSIOLOGIAE PLANTARUM

Comparative transcriptome analysis ofAgrobacterium tumefaciensin response to plant signal salicylic acid, indole-3-acetic acid and γ-amino butyric acid reveals signalling cross-talk andAgrobacterium-plant co-evolution

(2008) Ze-Chun Yuan et al.   CELLULAR MICROBIOLOGY

 -Hydroxybutyrate accumulation in Arabidopsis and tobacco plants is a general response to abiotic stress: putative regulation by redox balance and glyoxylate reductase isoforms

(2008) W. L. Allan et al.   JOURNAL OF EXPERIMENTAL BOTANY

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

GABAA receptor trafficking and its role in the dynamic modulation of neuronal inhibition

(2008) Tija C. Jacob et al.   NATURE REVIEWS NEUROSCIENCE

Biochemical Mechanism on GABA Accumulation During Fruit Development in Tomato

(2008) Takashi Akihiro et al.   PLANT AND CELL PHYSIOLOGY

Characterization of the TaALMT1 Protein as an Al3+-Activated Anion Channel in Transformed Tobacco (Nicotiana tabacum L.) Cells

(2008) Wen-Hao Zhang et al.   PLANT AND CELL PHYSIOLOGY

Characterization of the ABA-regulated global responses to dehydration in Arabidopsis by metabolomics

(2008) Kaoru Urano et al.   PLANT JOURNAL

Nitrogen Recycling and Remobilization Are Differentially Controlled by Leaf Senescence and Development Stage in Arabidopsis under Low Nitrogen Nutrition

(2008) C. Diaz et al.   PLANT PHYSIOLOGY

Novel Properties of the Wheat Aluminum Tolerance Organic Acid Transporter (TaALMT1) Revealed by Electrophysiological Characterization in Xenopus Oocytes: Functional and Structural Implications

(2008) M. A. Pineros et al.   PLANT PHYSIOLOGY

Mutants of GABA Transaminase (POP2) Suppress the Severe Phenotype of succinic semialdehyde dehydrogenase (ssadh) Mutants in Arabidopsis

(2008) Frank Ludewig et al.   PLoS One

The role and the mechanism of γ-aminobutyric acid during central nervous system development

(2008) Ke Li et al.   Neuroscience Bulletin

Contribution of the GABA shunt to hypoxia-induced alanine accumulation in roots of Arabidopsis thaliana

(2007) Y. Miyashita et al.   PLANT AND CELL PHYSIOLOGY

Highway or byway: the metabolic role of the GABA shunt in plants

(2007) Aaron Fait et al.   TRENDS IN PLANT SCIENCE