Immune tolerance in liver disease

Macrophage heterogeneity in liver injury and fibrosis

(2014) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

Expression of inhibitory markers is increased on effector memory T cells during hepatitis C virus/HIV coinfection as compared to hepatitis C virus or HIV monoinfection

(2013) Banishree Saha et al.   AIDS

Inhibition of the type I immune responses of human monocytes by IFN-α and IFN-β

(2013) Roelof A. de Paus et al.   CYTOKINE

Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion

(2013) Bastian Höchst et al.   JOURNAL OF HEPATOLOGY

Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma

(2013) Tamar Kapanadze et al.   JOURNAL OF HEPATOLOGY

CD141+ myeloid dendritic cells are enriched in healthy human liver

(2013) Aoife Kelly et al.   JOURNAL OF HEPATOLOGY

Hepatic Stellate Cells Preferentially Induce Foxp3+ Regulatory T Cells by Production of Retinoic Acid

(2013) R. M. Dunham et al.   JOURNAL OF IMMUNOLOGY

AAV8 Induces Tolerance in Murine Muscle as a Result of Poor APC Transduction, T Cell Exhaustion, and Minimal MHCI Upregulation on Target Cells

(2013) Lauren E Mays et al.   MOLECULAR THERAPY

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection

(2013) Li-Rung Huang et al.   NATURE IMMUNOLOGY

The kinship of neutrophils and granulocytic myeloid-derived suppressor cells in cancer: Cousins, siblings or twins?

(2013) Sven Brandau et al.   SEMINARS IN CANCER BIOLOGY

Human Hepatic Stellate Cells Inhibit T-Cell Response Through B7-H1 Pathway

(2013) Ronald Charles et al.   TRANSPLANTATION

PD-L1 Signal on Liver Dendritic Cells Is Critical for Foxp3+CD4+CD25+ Treg and Liver Tolerance Induction in Mice

(2013) H. Liu et al.   TRANSPLANTATION PROCEEDINGS

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

(2013) Helen M. Lazear et al.   PLoS Pathogens

Multipotent Human Mesenchymal Stromal Cells Mediate Expansion of Myeloid-Derived Suppressor Cells via Hepatocyte Growth Factor/c-Met and STAT3

(2013) B. Linju Yen et al.   Stem Cell Reports

MDSC

(2012) Bernard J.C. Macatangay et al.   AIDS

Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection

(2012) Victoria M. Velazquez et al.   HEPATOLOGY

Human blood dendritic cell antigen 3 (BDCA3)+dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus

(2012) Sachiyo Yoshio et al.   HEPATOLOGY

Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

(2012) Muzlifah Haniffa et al.   IMMUNITY

Myeloid-derived Suppressor Cells Adhere to Physiologic STAT3- vs STAT5-dependent Hematopoietic Programming, Establishing Diverse Tumor-Mediated Mechanisms of Immunologic Escape

(2012) Peter A. Cohen et al.   IMMUNOLOGICAL INVESTIGATIONS

IDO-Competent-DCs Induced by IFN-γ Attenuate Acute Rejection in rat Liver Transplantation

(2012) Xing Sun et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection

(2012) Koyo Higashitani et al.   JOURNAL OF GASTROENTEROLOGY

IL-27 Production and STAT3-Dependent Upregulation of B7-H1 Mediate Immune Regulatory Functions of Liver Plasmacytoid Dendritic Cells

(2012) B. M. Matta et al.   JOURNAL OF IMMUNOLOGY

Defective CD8 T Cell Responses in Aged Mice Are Due to Quantitative and Qualitative Changes in Virus-Specific Precursors

(2012) V. Decman et al.   JOURNAL OF IMMUNOLOGY

Immunosuppressive functions of hepatic myeloid-derived suppressor cells of normal mice and in a murine model of chronic hepatitis B virus

(2011) S. Chen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cross-presentation of antigen by diverse subsets of murine liver cells

(2011) Mohammad R. Ebrahimkhani et al.   HEPATOLOGY

Tolerogenic dendritic cells and their role in transplantation

(2011) Mohamed Ezzelarab et al.   SEMINARS IN IMMUNOLOGY

Differential cytokine responses from primary human Kupffer cells following infection with wild-type or vaccine strain yellow fever virus

(2011) Sara E. Woodson et al.   VIROLOGY

Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD

(2011) Lin Qu et al.   PLoS Pathogens

Apoptotic cells attenuate fulminant hepatitis by priming Kupffer cells to produce interleukin-10 through membrane-bound TGF-β

(2010) Minggang Zhang et al.   HEPATOLOGY

Virus-specific CD4+ T cell responses in chronic HCV infection in blood and liver identified by antigen-specific upregulation of CD154

(2010) Mareike Mueller et al.   JOURNAL OF HEPATOLOGY

Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection

(2010) José-Ignacio Riezu-Boj et al.   JOURNAL OF HEPATOLOGY

Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver

(2010) Y. H. Oo et al.   JOURNAL OF IMMUNOLOGY

Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection

(2010) K. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of allogeneic T-cell response by Kupffer cells expressing indoleamine 2,3-dioxygenase

(2010) Mao-Lin Yan   WORLD JOURNAL OF GASTROENTEROLOGY

Hepatitis C Virus (HCV) Evades NKG2D-Dependent NK Cell Responses through NS5A-Mediated Imbalance of Inflammatory Cytokines

(2010) Damien Sène et al.   PLoS Pathogens

Interferon- -triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells

(2009) B. Jurgens et al.   BLOOD

The Dendritic Cell-like Functions of IFN-Producing Killer Dendritic Cells Reside in the CD11b+ Subset and Are Licensed by Tumor Cells

(2009) M. Terme et al.   CANCER RESEARCH

Kupffer Cell Suppression of CD8+ T Cells in Human Hepatocellular Carcinoma Is Mediated by B7-H1/Programmed Death-1 Interactions

(2009) K. Wu et al.   CANCER RESEARCH

Liver Sinusoidal Endothelial Cell Lectin, LSECtin, Negatively Regulates Hepatic T-Cell Immune Response

(2009) Li Tang et al.   GASTROENTEROLOGY

Hepatitis C Virus Core Protein Subverts the Antiviral Activities of Human Kupffer Cells

(2009) Zhengkun Tu et al.   GASTROENTEROLOGY

Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3− regulatory T cells suppressing autoimmune hepatitis

(2009) Nils Kruse et al.   HEPATOLOGY

Mechanistic insights into immunomodulation by hepatic stellate cells in mice: A critical role of interferon-γ signaling

(2009) Horng-Ren Yang et al.   HEPATOLOGY

Up-Regulation of IRAK-M is Essential for Endotoxin Tolerance Induced by a Low Dose of Lipopolysaccharide in Kupffer Cells

(2008) Zuo-Jin Liu et al.   JOURNAL OF SURGICAL RESEARCH

Role of Kupffer cells in the induction of tolerance of orthotopic liver transplantation in rats

(2008) Yong Chen et al.   LIVER TRANSPLANTATION

Decreases in circulating CD4+CD25hiFOXP3+cells and increases in intragraft FOXP3+cells accompany allograft rejection in pediatric liver allograft recipients

(2008) Fabien Stenard et al.   PEDIATRIC TRANSPLANTATION

Hepatic Stellate Cells Preferentially Expand Allogeneic CD4+CD25+FoxP3+ Regulatory T Cells in an IL-2-Dependent Manner

(2008) Guoping Jiang et al.   TRANSPLANTATION