DNA-modifying enzyme reaction-based biosensors for disease diagnostics: recent biotechnological advances and future perspectives

Application of hairpin DNA-based biosensors with various signal amplification strategies in clinical diagnosis

(2019) Rozita Abolhasan et al.   BIOSENSORS & BIOELECTRONICS

A microRNA-triggered self-powered DNAzyme walker operating in living cells

(2019) Chang Liu et al.   BIOSENSORS & BIOELECTRONICS

Nanomaterials as efficient platforms for sensing DNA

(2019) Kumar Vikrant et al.   BIOMATERIALS

The construction of Mycobacterium tuberculosis 16S rDNA MSPQC sensor based on Exonuclease III-assisted cyclic signal amplification

(2019) Jialin Zhang et al.   BIOSENSORS & BIOELECTRONICS

Twin target self-amplification-based DNA machine for highly sensitive detection of cancer-related gene

(2018) Huo Xu et al.   ANALYTICA CHIMICA ACTA

Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Triggered Isothermal Amplification for Site-Specific Nucleic Acid Detection

(2018) Mengqi Huang et al.   ANALYTICAL CHEMISTRY

Palindromic Molecule Beacon-Based Cascade Amplification for Colorimetric Detection of Cancer Genes

(2018) Zhi-Fa Shen et al.   ANALYTICAL CHEMISTRY

Exponential isothermal amplification of nucleic acids and amplified assays for proteins, cells, and enzyme activities

(2018) Michael S Reid et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Signal-on electrochemiluminescence biosensor for microRNA-319a detection based on two-stage isothermal strand-displacement polymerase reaction

(2018) Minghui Wang et al.   BIOSENSORS & BIOELECTRONICS

Stochastic DNA walker for electrochemical biosensing sensitized with gold nanocages@graphene nanoribbons

(2018) Qiumei Feng et al.   BIOSENSORS & BIOELECTRONICS

An ultrasensitive electrochemiluminescence biosensor for detection of MicroRNA by in-situ electrochemically generated copper nanoclusters as luminophore and TiO 2 as coreaction accelerator

(2018) Hongxia Liao et al.   BIOSENSORS & BIOELECTRONICS

Label-free and ultrasensitive detection of polynucleotide kinase activity at the single-cell level

(2018) Meng Liu et al.   CHEMICAL COMMUNICATIONS

Colorimetric detection of DNA at the nanomolar level based on enzyme-induced gold nanoparticle de-aggregation

(2018) Qingling Liu et al.   MICROCHIMICA ACTA

Rapid and ultrasensitive detection of microRNA based on strand displacement amplification-mediated entropy-driven circuit reaction

(2018) Shu Ou et al.   SENSORS AND ACTUATORS B-CHEMICAL

Reverse strand-displacement amplification strategy for rapid detection of p53 gene

(2018) Lisha Wang et al.   TALANTA

A simple enzyme-assisted cascade amplification strategy for ultrasensitive and label-free detection of DNA

(2018) Kun Wang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

An overview of biomolecules, immobilization methods and support materials of biosensors

(2018) Melis Asal et al.   Sensor Review

Harnessing a previously unidentified capability of bacterial allosteric transcription factors for sensing diverse small molecules in vitro

(2018) Jiaqian Cao et al.   Science Advances

Cancer diagnosis using nanomaterials based electrochemical nanobiosensors

(2018) Majid Sharifi et al.   BIOSENSORS & BIOELECTRONICS

Label-free, non-enzymatic and ultrasensitive electrochemical nucleic acid biosensing by tandem DNA-fueled target recycling and hybridization chain reaction

(2017) Shufeng Liu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Exponential rolling circle amplification and its sensing application for highly sensitive DNA detection of tumor suppressor gene

(2017) Huo Xu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme

(2017) Jiangyu Yan et al.   Nature Communications

Sensitive DNA detection using cascade amplification strategy based on conjugated polyelectrolytes and hybridization chain reaction

(2017) Biqing Bao et al.   RSC Advances

DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase

(2017) Jing Wu et al.   Scientific Reports

Enzyme-based logic gates and circuits—analytical applications and interfacing with electronics

(2016) Evgeny Katz et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Sensitive Detection of Polynucleotide Kinase Activity by Paper-Based Fluorescence Assay with λ Exonuclease Assistance

(2016) Hua Zhang et al.   ANALYTICAL CHEMISTRY

Ultrasensitive Label-Free Resonance Rayleigh Scattering Aptasensor for Hg2+ Using Hg2+-Triggered Exonuclease III-Assisted Target Recycling and Growth of G-Wires for Signal Amplification

(2016) Wang Ren et al.   ANALYTICAL CHEMISTRY

Highly Selective and Sensitive Electrochemiluminescence Biosensor for p53 DNA Sequence Based on Nicking Endonuclease Assisted Target Recycling and Hyperbranched Rolling Circle Amplification

(2016) Linlin Yang et al.   ANALYTICAL CHEMISTRY

Invading stacking primer: A trigger for high-efficiency isothermal amplification reaction with superior selectivity for detecting microRNA variants

(2016) Weipeng Liu et al.   BIOSENSORS & BIOELECTRONICS

Ultrasensitive and rapid detection of miRNA with three-way junction structure-based trigger-assisted exponential enzymatic amplification

(2016) Ying Xu et al.   BIOSENSORS & BIOELECTRONICS

Intelligent DNA machine for the ultrasensitive colorimetric detection of nucleic acids

(2016) Jianguo Xu et al.   BIOSENSORS & BIOELECTRONICS

A signal amplification electrochemical aptasensor for the detection of breast cancer cell via free-running DNA walker

(2016) Shuxian Cai et al.   BIOSENSORS & BIOELECTRONICS

G-quadruplex DNAzyme-based chemiluminescence biosensing platform based on dual signal amplification for label-free and sensitive detection of protein

(2016) Pei Zou et al.   BIOSENSORS & BIOELECTRONICS

Fluorometric detection of mutant DNA oligonucleotide based on toehold strand displacement-driving target recycling strategy and exonuclease III-assisted suppression

(2016) Hong Guo Chen et al.   BIOSENSORS & BIOELECTRONICS

A label-free fluorescence strategy for selective detection of nicotinamide adenine dinucleotide based on a dumbbell-like probe with low background noise

(2016) Xuexu Chen et al.   BIOSENSORS & BIOELECTRONICS

Aptamer-based nanobiosensors

(2016) Yeon Seok Kim et al.   BIOSENSORS & BIOELECTRONICS

New function of exonuclease and highly sensitive label-free colorimetric DNA detection

(2016) Hongbo Li et al.   BIOSENSORS & BIOELECTRONICS

Target-triggered cascade recycling amplification for label-free detection of microRNA and molecular logic operations

(2016) Sai Bi et al.   CHEMICAL COMMUNICATIONS

RCA-Based Biosensor for Electrical and Colorimetric Detection of Pathogen DNA

(2016) Jaepil Jeong et al.   Nanoscale Research Letters

Optical Biosensors for the Detection of Pathogenic Microorganisms

(2016) Seung Min Yoo et al.   TRENDS IN BIOTECHNOLOGY

Label-free detection of microRNA based on coupling multiple isothermal amplification techniques

(2016) Xiangjiang Zheng et al.   Scientific Reports

RCA-Based Biosensor for Electrical and Colorimetric Detection of Pathogen DNA

(2016) Jaepil Jeong et al.   Nanoscale Research Letters

A novel and versatile nanomachine for ultrasensitive and specific detection of microRNAs based on molecular beacon initiated strand displacement amplification coupled with catalytic hairpin assembly with DNAzyme formation

(2015) Yurong Yan et al.   ANALYST

Entropy Beacon: A Hairpin-Free DNA Amplification Strategy for Efficient Detection of Nucleic Acids

(2015) Yifan Lv et al.   ANALYTICAL CHEMISTRY

Dual Functional Graphene Derivative-Based Electrochemical Platforms for Detection of the TP53 Gene with Single Nucleotide Polymorphism Selectivity in Biological Samples

(2015) Berta Esteban-Fernández de Ávila et al.   ANALYTICAL CHEMISTRY

DNA-Fueled Molecular Machine Enables Enzyme-Free Target Recycling Amplification for Electronic Detection of MicroRNA from Cancer Cells with Highly Minimized Background Noise

(2015) Kai Shi et al.   ANALYTICAL CHEMISTRY

Bridging the Two Worlds: A Universal Interface between Enzymatic and DNA Computing Systems

(2015) Shay Mailloux et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Molecular Imaging of MicroRNA in Living Cells by DNA-Programmed Nanoparticle Disassembly

(2015) Xuewen He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multispot array combined with S1 nuclease-mediated elimination of unpaired nucleotides

(2015) Seung Min Yoo et al.   BioChip Journal

Label-free and sensitive detection of T4 polynucleotide kinase activity via coupling DNA strand displacement reaction with enzymatic-aided amplification

(2015) Rui Cheng et al.   BIOSENSORS & BIOELECTRONICS

Amplified fluorescent aptasensor through catalytic recycling for highly sensitive detection of ochratoxin A

(2015) Yin Wei et al.   BIOSENSORS & BIOELECTRONICS

An amplified electrochemical immunosensor based on in situ-produced 1-naphthol as electroactive substance and graphene oxide and Pt nanoparticles functionalized CeO2 nanocomposites as signal enhancer

(2015) Zhe-Han Yang et al.   BIOSENSORS & BIOELECTRONICS

Electrochemiluminescence biosensor for ultrasensitive determination of ochratoxin A in corn samples based on aptamer and hyperbranched rolling circle amplification

(2015) Linlin Yang et al.   BIOSENSORS & BIOELECTRONICS

Detection of microRNA in clinical tumor samples by isothermal enzyme-free amplification and label-free graphene oxide-based SYBR Green I fluorescence platform

(2015) Debin Zhu et al.   BIOSENSORS & BIOELECTRONICS

A fluorescent biosensing platform based on the polydopamine nanospheres intergrating with Exonuclease III-assisted target recycling amplification

(2015) Weibing Qiang et al.   BIOSENSORS & BIOELECTRONICS

Fluorescence-based detection of single-nucleotide changes in RNA using graphene oxide and DNAzyme

(2015) Chaesun Hong et al.   CHEMICAL COMMUNICATIONS

A microRNA-activated molecular machine for non-enzymatic target recycling amplification detection of microRNA from cancer cells

(2015) Xin Li et al.   CHEMICAL COMMUNICATIONS

Isothermal Amplification of Nucleic Acids

(2015) Yongxi Zhao et al.   CHEMICAL REVIEWS

Direct potential resolution and simultaneous detection of cytosine and 5-methylcytosine based on the construction of polypyrrole functionalized graphene nanowall interface

(2015) Po Wang et al.   ELECTROCHEMISTRY COMMUNICATIONS

Reconfigurable and resettable arithmetic logic units based on magnetic beads and DNA

(2015) Siqi Zhang et al.   Nanoscale

MicroRNAs in platelet function and cardiovascular disease

(2015) David D. McManus et al.   Nature Reviews Cardiology

Electrochemical detection of aqueous Ag+ based on Ag+-assisted ligation reaction

(2015) Peng Miao et al.   Scientific Reports

Multiplexed and Amplified Electronic Sensor for the Detection of MicroRNAs from Cancer Cells

(2014) Cuiyun Yang et al.   ANALYTICAL CHEMISTRY

Toehold-initiated Rolling Circle Amplification for Visualizing Individual MicroRNAs In Situ in Single Cells

(2014) Ruijie Deng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Integration of graphene oxide and DNA as a universal platform for multiple arithmetic logic units

(2014) Kun Wang et al.   CHEMICAL COMMUNICATIONS

Physics-based enzyme design: Predicting binding affinity and catalytic activity

(2014) Sarah Sirin et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Ultrasensitive detection of 3′-5′ exonuclease enzymatic activity using molecular beacons

(2013) Xu Wu et al.   ANALYST

A sensitive electrochemical DNA biosensor for specific detection of Enterobacteriaceae bacteria by Exonuclease III-assisted signal amplification

(2013) Caihui Luo et al.   BIOSENSORS & BIOELECTRONICS

Target-induced self-assembly of DNA nanomachine on magnetic particle for multi-amplified biosensing of nucleic acid, protein, and cancer cell

(2013) Sai Bi et al.   BIOSENSORS & BIOELECTRONICS

Quadratic recycling amplification for label-free and sensitive visual detection of HIV DNA

(2013) Wenjiao Zhou et al.   BIOSENSORS & BIOELECTRONICS

An ultrasensitive homogeneous chemiluminescent assay for microRNAs

(2013) Huimin Deng et al.   CHEMICAL COMMUNICATIONS

Colorimetric detection of human papilloma virus by double isothermal amplification

(2013) Stefano Persano et al.   CHEMICAL COMMUNICATIONS

Aptamer degradation inhibition combined with DNAzyme cascade-based signal amplification for colorimetric detection of proteins

(2013) Jishan Li et al.   CHEMICAL COMMUNICATIONS

Application of DNA machine in amplified DNA detection

(2013) Hailong Li et al.   CHEMICAL COMMUNICATIONS

On the biophysics and kinetics of toehold-mediated DNA strand displacement

(2013) Niranjan Srinivas et al.   NUCLEIC ACIDS RESEARCH

A multicolor nano-immunosensor for the detection of multiple targets

(2013) Ming Shi et al.   RSC Advances

Rapid microRNA detection using power-free microfluidic chip: coaxial stacking effect enhances the sandwich hybridization

(2012) Hideyuki Arata et al.   ANALYST

Computational Protein Engineering: Bridging the Gap between Rational Design and Laboratory Evolution

(2012) Alexandre Barrozo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Real-Time Detection of Telomerase Activity Using the Exponential Isothermal Amplification of Telomere Repeat Assay

(2012) Leilei Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Homogeneous Label-Free Genotyping of Single Nucleotide Polymorphism Using Ligation-Mediated Strand Displacement Amplification with DNAzyme-Based Chemiluminescence Detection

(2011) Hong-Qi Wang et al.   ANALYTICAL CHEMISTRY

Detection of Single Nucleotide Polymorphisms by a Gold Nanowire-on-Film SERS Sensor Coupled with S1 Nuclease Treatment

(2011) Seung Min Yoo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Remote Toehold: A Mechanism for Flexible Control of DNA Hybridization Kinetics

(2011) Anthony J. Genot et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Combining a Nanowire SERRS Sensor and a Target Recycling Reaction for Ultrasensitive and Multiplex Identification of Pathogenic Fungi

(2011) Seung Min Yoo et al.   Small

Fluorescence Detection of Telomerase Activity in Cancer Cells Based on Isothermal Circular Strand-Displacement Polymerization Reaction

(2010) Caifeng Ding et al.   ANALYTICAL CHEMISTRY

Ultrasensitive Detection of microRNAs by Exponential Isothermal Amplification

(2010) Hongxia Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Control of DNA Strand Displacement Kinetics Using Toehold Exchange

(2009) David Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The cancer biomarker problem

(2008) Charles L. Sawyers   NATURE