Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration
Authors
Keywords
Cardiac fibrosis, Myocardial infarction, Pro-fibrotic signaling, Anti-fibrotic therapy, Cardiac regeneration
Journal
CELL AND TISSUE RESEARCH
Volume 365, Issue 3, Pages 563-581
Publisher
Springer Nature
Online
2016-06-22
DOI
10.1007/s00441-016-2431-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis
- (2016) Luis Luna-Zurita et al. CELL
- Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming
- (2016) Yang Zhou et al. Cell Stem Cell
- Expandable Cardiovascular Progenitor Cells Reprogrammed from Fibroblasts
- (2016) Yu Zhang et al. Cell Stem Cell
- Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors
- (2016) Pratik A. Lalit et al. Cell Stem Cell
- Cardiac Regeneration Therapies – Targeting Neuregulin 1 Signalling
- (2016) Richard P. Harvey et al. Heart Lung and Circulation
- Non-coding RNAs as modulators of the cardiac fibroblast phenotype
- (2016) Maria-Teresa Piccoli et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Transcriptional control of cardiac fibroblast plasticity
- (2016) Janet K. Lighthouse et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The crossroads of inflammation, fibrosis, and arrhythmia following myocardial infarction
- (2016) Samantha D. Francis Stuart et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Fibroblast–myocyte coupling in the heart: Potential relevance for therapeutic interventions
- (2016) Emily Ongstad et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Integrins and integrin-related proteins in cardiac fibrosis
- (2016) Chao Chen et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Origins of cardiac fibroblasts
- (2016) Thomas Moore-Morris et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling
- (2016) Margaux A. Horn et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Matrix metalloproteinases as input and output signals for post-myocardial infarction remodeling
- (2016) Merry L. Lindsey et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Cardiac Niche Influences the Direct Reprogramming of Canine Fibroblasts into Cardiomyocyte-Like Cells
- (2016) Giacomo Palazzolo et al. Stem Cells International
- Ascorbic acid promotes the direct conversion of mouse fibroblasts into beating cardiomyocytes
- (2015) Mahmood Talkhabi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Simvastatin alleviates cardiac fibrosis induced by infarction via up-regulation of TGF-β receptor III expression
- (2015) Fei Sun et al. BRITISH JOURNAL OF PHARMACOLOGY
- In vivocardiac reprogramming using an optimal single polycistronic construct: Figure 1
- (2015) Hong Ma et al. CARDIOVASCULAR RESEARCH
- Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction
- (2015) José González-Santamaría et al. CARDIOVASCULAR RESEARCH
- Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails
- (2015) Yanbin Fu et al. CELL RESEARCH
- Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis
- (2015) Rafael Kramann et al. Cell Stem Cell
- Direct Reprogramming of Fibroblasts into Cardiomyocytes for Cardiac Regenerative Medicine
- (2015) Ji-Dong Fu et al. CIRCULATION JOURNAL
- Revisiting Cardiac Cellular CompositionNovelty and Significance
- (2015) Alexander R. Pinto et al. CIRCULATION RESEARCH
- Getting to the Heart of the Matter
- (2015) Andrew Leask CIRCULATION RESEARCH
- Recent advances in direct cardiac reprogramming
- (2015) Deepak Srivastava et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Programming and reprogramming a human heart cell
- (2015) M. Sahara et al. EMBO JOURNAL
- Interacting Resident Epicardium-Derived Fibroblasts and Recruited Bone Marrow Cells Form Myocardial Infarction Scar
- (2015) Adrián Ruiz-Villalba et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes
- (2015) Huanyu Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA-Mediated Reprogramming of Primary Adult Human Dermal Fibroblasts into c-kit+Cardiac Progenitor Cells
- (2015) Elizabeth D. Pratico et al. STEM CELLS AND DEVELOPMENT
- High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling
- (2015) Yuanbiao Zhao et al. Nature Communications
- Phosphodiesterase type 5 inhibitors: back and forward from cardiac indications
- (2015) C. Corinaldesi et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- Developmental Heterogeneity of Cardiac Fibroblasts Does Not Predict Pathological Proliferation and Activation
- (2014) Shah R. Ali et al. CIRCULATION RESEARCH
- Cardiogenic Genes Expressed in Cardiac Fibroblasts Contribute to Heart Development and Repair
- (2014) Milena B. Furtado et al. CIRCULATION RESEARCH
- Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors
- (2014) Y.-J. Nam et al. DEVELOPMENT
- MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures
- (2014) N. Muraoka et al. EMBO JOURNAL
- The functional diversity of essential genes required for mammalian cardiac development
- (2014) Christopher Clowes et al. GENESIS
- Connective Tissue Growth Factor Inhibition Attenuates Left Ventricular Remodeling and Dysfunction in Pressure Overload–Induced Heart Failure
- (2014) Zoltán Szabó et al. HYPERTENSION
- Macrophages are required for neonatal heart regeneration
- (2014) Arin B. Aurora et al. JOURNAL OF CLINICAL INVESTIGATION
- Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis
- (2014) Thomas Moore-Morris et al. JOURNAL OF CLINICAL INVESTIGATION
- Cardiac fibroblast in development and wound healing
- (2014) Arjun Deb et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Targeting cardiac fibroblasts to treat fibrosis of the heart: Focus on HDACs
- (2014) Katherine B. Schuetze et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Fibroblast–myocyte electrotonic coupling: Does it occur in native cardiac tissue?
- (2014) Peter Kohl et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- “Triplet” polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors
- (2014) Megumi Mathison et al. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
- The profibrotic role of endothelin-1: Is the door still open for the treatment of fibrotic diseases?
- (2014) Fernando Rodríguez-Pascual et al. LIFE SCIENCES
- The inflammatory response in myocardial injury, repair and remodelling
- (2014) Nikolaos G. Frangogiannis Nature Reviews Cardiology
- Noncoding RNAs and myocardial fibrosis
- (2014) Thomas Thum Nature Reviews Cardiology
- Inhibition of TGFβ Signaling Increases Direct Conversion of Fibroblasts to Induced Cardiomyocytes
- (2014) Jamie L. Ifkovits et al. PLoS One
- Small Molecules Enable Cardiac Reprogramming of Mouse Fibroblasts with a Single Factor, Oct4
- (2014) Haixia Wang et al. Cell Reports
- Anti‐Remodeling and Anti‐Fibrotic Effects of the Neuregulin‐1β Glial Growth Factor 2 in a Large Animal Model of Heart Failure
- (2014) Cristi L. Galindo et al. Journal of the American Heart Association
- Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis through inhibition of transforming growth factor β-induced Smad signaling
- (2014) Wei Gong et al. Frontiers of Medicine
- Direct Reprogramming of Fibroblasts into Myocytes to Reverse Fibrosis
- (2013) Naoto Muraoka et al. Annual Review of Physiology
- Thrombospondins, Potential Drug Targets for Cardiovascular Diseases
- (2013) Erja Mustonen et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome
- (2013) Nerea Hermida et al. CARDIOVASCULAR RESEARCH
- Accelerated direct reprogramming of fibroblasts into cardiomyocyte-like cells with the MyoD transactivation domain
- (2013) Hiroyuki Hirai et al. CARDIOVASCULAR RESEARCH
- The pathogenesis of cardiac fibrosis
- (2013) Ping Kong et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cardiac reprogramming: from mouse toward man
- (2013) Deepak Srivastava et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Association of Fibrosis With Mortality and Sudden Cardiac Death in Patients With Nonischemic Dilated Cardiomyopathy
- (2013) Ankur Gulati et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- IL-1 Induces Proinflammatory Leukocyte Infiltration and Regulates Fibroblast Phenotype in the Infarcted Myocardium
- (2013) A. Saxena et al. JOURNAL OF IMMUNOLOGY
- Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success
- (2013) Russell C. Addis et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Origin, development, and differentiation of cardiac fibroblasts
- (2013) Jacquelyn D. Lajiness et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Fibroblasts in myocardial infarction: A role in inflammation and repair
- (2013) Arti V. Shinde et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Myofibroblasts: Trust your heart and let fate decide
- (2013) Jennifer Davis et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Reprogramming of human fibroblasts toward a cardiac fate
- (2013) Y.-J. Nam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induction of human cardiomyocyte-like cells from fibroblasts by defined factors
- (2013) R. Wada et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Therapeutic Cardiac‐Targeted Delivery of miR‐1 Reverses Pressure Overload–Induced Cardiac Hypertrophy and Attenuates Pathological Remodeling
- (2013) Ioannis Karakikes et al. Journal of the American Heart Association
- Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State
- (2013) Ji-Dong Fu et al. Stem Cell Reports
- Thrombospondin-4, tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14: Novel extracellular matrix modulating factors in cardiac remodelling
- (2012) Erja Mustonen et al. ANNALS OF MEDICINE
- A Thrombospondin-Dependent Pathway for a Protective ER Stress Response
- (2012) Jeffrey M. Lynch et al. CELL
- Inefficient Reprogramming of Fibroblasts into Cardiomyocytes Using Gata4, Mef2c, and Tbx5
- (2012) Jenny X. Chen et al. CIRCULATION RESEARCH
- MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes
- (2012) Tilanthi M. Jayawardena et al. CIRCULATION RESEARCH
- Pan-epicardial lineage tracing reveals that epicardium derived cells give rise to myofibroblasts and perivascular cells during zebrafish heart regeneration
- (2012) Juan Manuel González-Rosa et al. DEVELOPMENTAL BIOLOGY
- ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC
- (2012) et al. EUROPEAN HEART JOURNAL
- Coronary perivascular fibrosis is associated with impairment of coronary blood flow in patients with non-ischemic heart failure
- (2012) Zhehao Dai et al. Journal of Cardiology
- A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells
- (2012) Stephanie Protze et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The myofibroblast matrix: implications for tissue repair and fibrosis
- (2012) Franco Klingberg et al. JOURNAL OF PATHOLOGY
- Clinical trials with endothelin receptor antagonists: What went wrong and where can we improve?
- (2012) Donald E. Kohan et al. LIFE SCIENCES
- Neuregulin induces CTGF expression in hypertrophic scarring fibroblasts
- (2012) Jun-Sub Kim et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Heart repair by reprogramming non-myocytes with cardiac transcription factors
- (2012) Kunhua Song et al. NATURE
- In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
- (2012) Li Qian et al. NATURE
- Myofibroblast-mediated mechanisms of pathological remodelling of the heart
- (2012) Karl T. Weber et al. Nature Reviews Cardiology
- Matricellular Proteins in Cardiac Adaptation and Disease
- (2012) Nikolaos G. Frangogiannis PHYSIOLOGICAL REVIEWS
- (Pro)renin Receptor Triggers Distinct Angiotensin II-Independent Extracellular Matrix Remodeling and Deterioration of Cardiac Function
- (2012) Anne-Mari Moilanen et al. PLoS One
- The Extracellular Matrix Modulates Fibroblast Phenotype and Function in the Infarcted Myocardium
- (2012) Marcin Dobaczewski et al. Journal of Cardiovascular Translational Research
- Lack of Fibronectin-EDA Promotes Survival and Prevents Adverse Remodeling and Heart Function Deterioration After Myocardial Infarction
- (2011) Fatih Arslan et al. CIRCULATION RESEARCH
- Intramyocardial BNP Gene Delivery Improves Cardiac Function Through Distinct Context-Dependent Mechanisms
- (2011) Anne-Mari Moilanen et al. Circulation-Heart Failure
- The Single-Molecule Mechanics of the Latent TGF-β1 Complex
- (2011) Lara Buscemi et al. CURRENT BIOLOGY
- Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair
- (2011) Jinzhu Duan et al. EMBO JOURNAL
- Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure
- (2011) Mihaela Gherghiceanu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- MiR-133a regulates collagen 1A1: Potential role of miR-133a in myocardial fibrosis in angiotensin II-dependent hypertension
- (2011) Giovanna Castoldi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Platelet-derived growth factor involvement in myocardial remodeling following infarction
- (2011) Wenyuan Zhao et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
- (2011) Jem A. Efe et al. NATURE CELL BIOLOGY
- Transient Regenerative Potential of the Neonatal Mouse Heart
- (2011) E. R. Porrello et al. SCIENCE
- Antifibrotic properties of c-Ski and its regulation of cardiac myofibroblast phenotype and contractility
- (2010) Ryan H. Cunnington et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Tenascin-C may aggravate left ventricular remodeling and function after myocardial infarction in mice
- (2010) Tomohiro Nishioka et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Tissue Renin-Angiotensin-Aldosterone Systems: Targets for Pharmacological Therapy
- (2010) Michael Bader Annual Review of Pharmacology and Toxicology
- Beta2-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation
- (2010) Pablo Aránguiz-Urroz et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Electrical remodelling precedes heart failure in an endothelin-1-induced model of cardiomyopathy
- (2010) Erin E. Mueller et al. CARDIOVASCULAR RESEARCH
- Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors
- (2010) Masaki Ieda et al. CELL
- Smad3 Signaling Critically Regulates Fibroblast Phenotype and Function in Healing Myocardial Infarction
- (2010) Marcin Dobaczewski et al. CIRCULATION RESEARCH
- Origins of Cardiac Fibroblasts
- (2010) Elisabeth M. Zeisberg et al. CIRCULATION RESEARCH
- Potential Therapeutic Targets for Cardiac Fibrosis
- (2010) Andrew Leask CIRCULATION RESEARCH
- A Dynamic Notch Injury Response Activates Epicardium and Contributes to Fibrosis Repair
- (2010) Jamie L. Russell et al. CIRCULATION RESEARCH
- GATA-4 Is an Angiogenic Survival Factor of the Infarcted Heart
- (2010) Jaana Rysä et al. Circulation-Heart Failure
- Renin, (pro)renin and receptor: an update
- (2010) Genevieve Nguyen CLINICAL SCIENCE
- The origin of fibroblasts and mechanism of cardiac fibrosis
- (2010) Guido Krenning et al. JOURNAL OF CELLULAR PHYSIOLOGY
- TGF-β activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II–infused mice
- (2010) Yu Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- Transforming growth factor (TGF)-β signaling in cardiac remodeling
- (2010) Marcin Dobaczewski et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes
- (2010) Kazu Kikuchi et al. NATURE
- Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
- (2010) Chris Jopling et al. NATURE
- Epidemiology and risk profile of heart failure
- (2010) Anh L. Bui et al. Nature Reviews Cardiology
- Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines
- (2009) Hongli Shan et al. CARDIOVASCULAR RESEARCH
- Cardiac Fibroblast
- (2009) Colby A. Souders et al. CIRCULATION RESEARCH
- MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts
- (2009) Scot J. Matkovich et al. CIRCULATION RESEARCH
- Divergent Effects of Losartan and Metoprolol on Cardiac Remodeling, C-kit+Cells, Proliferation and Apoptosis in the Left Ventricle after Myocardial Infarction
- (2009) Raisa Serpi et al. CTS-Clinical and Translational Science
- TIMPs and cardiac remodeling: ‘Embracing the MMP-independent-side of the family’
- (2009) Davy Vanhoutte et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Myocardial remodeling after infarction: the role of myofibroblasts
- (2009) Susanne W. M. van den Borne et al. Nature Reviews Cardiology
- Cardiac fibroblasts: At the heart of myocardial remodeling
- (2009) Karen E. Porter et al. PHARMACOLOGY & THERAPEUTICS
- Thrombospondin-4 expression is rapidly upregulated by cardiac overload
- (2008) Erja Mustonen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Panoramic imaging reveals basic mechanisms of induction and termination of ventricular tachycardia in rabbit heart with chronic infarction: Implications for low-voltage cardioversion
- (2008) Crystal M. Ripplinger et al. HEART RHYTHM
- The let-7 family of microRNAs
- (2008) Sarah Roush et al. TRENDS IN CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now