Tangential flow filtration of haptoglobin

Haptoglobin Therapeutics and Compartmentalization of Cell-Free Hemoglobin Toxicity

(2020) Paul W. Buehler et al.   TRENDS IN MOLECULAR MEDICINE

Novel manufacturing method for producing apohemoglobin and its biophysical properties

(2019) Ivan S. Pires et al.   BIOTECHNOLOGY AND BIOENGINEERING

Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics

(2018) Christian A. Schaer et al.   BMC BIOTECHNOLOGY

When might transferrin, hemopexin or haptoglobin administration be of benefit following the transfusion of red blood cells?

(2018) Paul W. Buehler et al.   CURRENT OPINION IN HEMATOLOGY

Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction

(2018) John D. Belcher et al.   PLoS One

The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation

(2017) H. Yang et al.   JOURNAL OF INTERNAL MEDICINE

Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis

(2016) Christian A. Schaer et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Haptoglobin or Hemopexin Therapy Prevents Acute Adverse Effects of Resuscitation After Prolonged Storage of Red CellsClinical Perspective

(2016) Jan A. Graw et al.   CIRCULATION

Hemoglobinuria-related acute kidney injury is driven by intrarenal oxidative reactions triggering a heme toxicity response

(2016) J W Deuel et al.   Cell Death & Disease

Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders

(2015) Ann Smith et al.   Frontiers in Physiology

Haptoglobin testing in hemolysis: Measurement and interpretation

(2014) Andrew W.Y. Shih et al.   AMERICAN JOURNAL OF HEMATOLOGY

Haptoglobin, hemopexin, and related defense pathways—basic science, clinical perspectives, and drug development

(2014) Dominik J. Schaer et al.   Frontiers in Physiology

Human Hp1-1 and Hp2-2 Phenotype-Specific Haptoglobin Therapeutics Are Both Effective In Vitro and in Guinea Pigs to Attenuate Hemoglobin Toxicity

(2013) Miriam Lipiski et al.   ANTIOXIDANTS & REDOX SIGNALING

Haptoglobin Preferentially Binds β but Not α Subunits Cross-Linked Hemoglobin Tetramers with Minimal Effects on Ligand and Redox Reactions

(2013) Yiping Jia et al.   PLoS One

Heme binding to human alpha-1 proteinase inhibitor

(2012) Elena Karnaukhova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

(2012) D. J. Schaer et al.   BLOOD

Alpha-2-macroglobulin: A physiological guardian

(2012) Ahmed A. Rehman et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy

(2012) Jin Hyen Baek et al.   JOURNAL OF CLINICAL INVESTIGATION

Haptoglobin: the hemoglobin detoxifier in plasma

(2012) Abdu I. Alayash et al.   TRENDS IN BIOTECHNOLOGY

A Simple and Rapid Procedure for Purification of Haptoglobin from Human Plasma Fraction IV

(2011) Lijing Sun et al.   ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY

Haptoglobin: Old protein with new functions

(2010) Abdu I. Alayash   CLINICA CHIMICA ACTA

Haptoglobin: Basic and Clinical Aspects

(2009) Andrew P. Levy et al.   ANTIOXIDANTS & REDOX SIGNALING

Receptor targeting of hemoglobin mediated by the haptoglobins: roles beyond heme scavenging

(2009) M. J. Nielsen et al.   BLOOD

Characterization of high molecular weight multimeric states of human haptoglobin and hemoglobin-based oxygen carriers by high-mass MALDI MS

(2009) Tatiana Pimenova et al.   JOURNAL OF SEPARATION SCIENCE

Human haptoglobin structure and function - a molecular modelling study

(2008) F. Polticelli et al.   FEBS Journal

α2-Macroglobulin and Haptoglobin Suppress Amyloid Formation by Interacting with Prefibrillar Protein Species

(2008) Justin J. Yerbury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY