Function and Regulation of IL-36 Signaling in Inflammatory Diseases and Cancer Development
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Function and Regulation of IL-36 Signaling in Inflammatory Diseases and Cancer Development
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-12-04
DOI
10.3389/fcell.2019.00317
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Polymorphisms in IL36G gene are associated with plaque psoriasis
- (2019) Tanel Traks et al. BMC Medical Genetics
- Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis
- (2019) Hervé Bachelez et al. NEW ENGLAND JOURNAL OF MEDICINE
- IL-36 Cytokines: Regulators of Inflammatory Responses and Their Emerging Role in Immunology of Reproduction
- (2019) José Murrieta-Coxca et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGF-β type 2 receptor–mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis
- (2019) Tieshi Li et al. Science Translational Medicine
- IL-1 Family Members in Cancer; Two Sides to Every Story
- (2019) Kevin J. Baker et al. Frontiers in Immunology
- Interleukin-36 promotes systemic Type-I IFN responses in severe forms of psoriasis
- (2019) Marika Catapano et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction
- (2019) Eirini Giannoudaki et al. Nature Communications
- MEK-ERK signaling diametrically controls the stimulation of IL-23p19 and EBI3 expression in epithelial cells by IL-36γ
- (2018) Glen M Scholz et al. IMMUNOLOGY AND CELL BIOLOGY
- Regnase-1, an Immunomodulator, Limits the IL-36/IL-36R Autostimulatory Loop in Keratinocytes to Suppress Skin Inflammation
- (2018) Mikiro Takaishi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Knockout of the interleukin-36 receptor protects against renal ischemia-reperfusion injury by reduction of proinflammatory cytokines
- (2018) Hirofumi Nishikawa et al. KIDNEY INTERNATIONAL
- A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage
- (2018) Vu L. Ngo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Association of IL-36γ with tertiary lymphoid structures and inflammatory immune infiltrates in human colorectal cancer
- (2018) Aliyah M. Weinstein et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice with Chronic Intestinal Inflammation
- (2018) Kristina Scheibe et al. GASTROENTEROLOGY
- Targeted codelivery of doxorubicin and IL-36γ expression plasmid for an optimal chemo-gene combination therapy against cancer lung metastasis
- (2018) Yichao Chen et al. Nanomedicine-Nanotechnology Biology and Medicine
- IL-36γ has proinflammatory effects on human endothelial cells
- (2017) Charlie Bridgewood et al. EXPERIMENTAL DERMATOLOGY
- Neutrophil extracellular traps can serve as platforms for processing and activation of IL-1 family cytokines
- (2017) Danielle M. Clancy et al. FEBS Journal
- Regulation and function of interleukin-36 cytokines
- (2017) Esen Yonca Bassoy et al. IMMUNOLOGICAL REVIEWS
- IL-36γ Induced by the TLR3-SLUG-VDR Axis Promotes Wound Healing via REG3A
- (2017) Ziwei Jiang et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis
- (2017) Hsi-Hua Chi et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- IL-36γ is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and -negative bacterial pneumonia
- (2017) M A Kovach et al. Mucosal Immunology
- IL-36γ signaling controls the induced regulatory T cell–Th9 cell balance via NFκB activation and STAT transcription factors
- (2017) A Harusato et al. Mucosal Immunology
- Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ
- (2017) Joseph S. Ainscough et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target
- (2017) Satveer K. Mahil et al. Science Translational Medicine
- IL-36α suppresses proliferation of ovarian cancer cells
- (2017) Lei Chang et al. TUMOR BIOLOGY
- IL-36 cytokines in autoimmunity and inflammatory disease
- (2017) Liping Ding et al. Oncotarget
- Interleukin-36γ and IL-36 receptor signaling mediate impaired host immunity and lung injury in cytotoxic Pseudomonas aeruginosa pulmonary infection: Role of prostaglandin E2
- (2017) Tetsuji Aoyagi et al. PLoS Pathogens
- Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment
- (2017) Aliyah M. Weinstein et al. OncoImmunology
- Distinct expression of interleukin (IL)-36α, βandγ, their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and Crohn's disease
- (2016) M.-A. Boutet et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Interleukin-36 potently stimulates human M2 macrophages, Langerhans cells and keratinocytes to produce pro-inflammatory cytokines
- (2016) Damien Dietrich et al. CYTOKINE
- IL-36R signalling activates intestinal epithelial cells and fibroblasts and promotes mucosal healing in vivo
- (2016) Kristina Scheibe et al. GUT
- Increased Expression of Interleukin-36, a Member of the Interleukin-1 Cytokine Family, in Inflammatory Bowel Disease
- (2016) Atsushi Nishida et al. INFLAMMATORY BOWEL DISEASES
- Structural and Functional Attributes of the Interleukin-36 Receptor
- (2016) Guanghui Yi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IRF6 Regulates the Expression of IL-36γ by Human Oral Epithelial Cells in Response toPorphyromonas gingivalis
- (2016) Jennifer Huynh et al. JOURNAL OF IMMUNOLOGY
- IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation
- (2016) S E Russell et al. Mucosal Immunology
- Neutrophil Elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 Receptor antagonist
- (2016) Tom Macleod et al. Scientific Reports
- Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines
- (2016) Conor M. Henry et al. Cell Reports
- Tertiary Lymphoid Structures in Cancers: Prognostic Value, Regulation, and Manipulation for Therapeutic Intervention
- (2016) Catherine Sautès-Fridman et al. Frontiers in Immunology
- Prevalence of Inflammatory Bowel Disease Among Adults Aged ≥18 Years — United States, 2015
- (2016) James M. Dahlhamer et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN
- (2015) Maris Keermann et al. BMC GENOMICS
- IL-36γ Transforms the Tumor Microenvironment and Promotes Type 1 Lymphocyte-Mediated Antitumor Immune Responses
- (2015) Xuefeng Wang et al. CANCER CELL
- The interleukin (IL)-1 cytokine family – Balance between agonists and antagonists in inflammatory diseases
- (2015) Jennifer Palomo et al. CYTOKINE
- Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme
- (2015) Inna S. Afonina et al. IMMUNITY
- Expression of IL-36 family cytokines and IL-37 but not IL-38 is altered in psoriatic skin
- (2015) Maris Keermann et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage
- (2015) Oscar Medina-Contreras et al. JOURNAL OF IMMUNOLOGY
- IL-36γ (IL-1F9) Is a Biomarker for Psoriasis Skin Lesions
- (2015) Angelo Massimiliano D'Erme et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Regulation and function of interleukin-36 cytokines in homeostasis and pathological conditions
- (2015) Cem Gabay et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Comparative Genomic Profiling of Synovium Versus Skin Lesions in Psoriatic Arthritis
- (2015) Jennifer Belasco et al. Arthritis & Rheumatology
- IL-36γ Sustains a Proinflammatory Self-amplifying Loop with IL-17C in Anti-TNF–induced Psoriasiform Skin Lesions of Patients with Crohnʼs Disease
- (2014) Matthias Friedrich et al. INFLAMMATORY BOWEL DISEASES
- Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor
- (2014) Sebastian Günther et al. JOURNAL OF IMMUNOLOGY
- IL-36 Promotes Myeloid Cell Infiltration, Activation, and Inflammatory Activity in Skin
- (2014) A. M. Foster et al. JOURNAL OF IMMUNOLOGY
- Alarmin Function of Cathelicidin Antimicrobial Peptide LL37 through IL-36γ Induction in Human Epidermal Keratinocytes
- (2014) Na Li et al. JOURNAL OF IMMUNOLOGY
- Blockade of IL-36 Receptor Signaling Does Not Prevent from TNF-Induced Arthritis
- (2014) Anja Derer et al. PLoS One
- Decreased expression of interleukin-36α correlates with poor prognosis in hepatocellular carcinoma
- (2013) Qiu-Zhong Pan et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- 253
- (2013) Yu Sun et al. CYTOKINE
- The Interleukin-1 Family: Back to the Future
- (2013) Cecilia Garlanda et al. IMMUNITY
- NovelIL36RNmutation in a Japanese case of early onset generalized pustular psoriasis
- (2013) Nobuo Kanazawa et al. JOURNAL OF DERMATOLOGY
- The Majority of Generalized Pustular Psoriasis without Psoriasis Vulgaris Is Caused by Deficiency of Interleukin-36 Receptor Antagonist
- (2013) Kazumitsu Sugiura et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Biology of IL-36 cytokines and their role in disease
- (2013) Mark S. Gresnigt et al. SEMINARS IN IMMUNOLOGY
- The severity of experimental arthritis is independent of IL-36 receptor signaling
- (2013) Céline Lamacchia et al. ARTHRITIS RESEARCH & THERAPY
- New Insights in the Immunobiology of IL-1 Family Members
- (2013) Frank L. van de Veerdonk et al. Frontiers in Immunology
- The novel cytokine interleukin-36α is expressed in psoriatic and rheumatoid arthritis synovium
- (2012) Silke Frey et al. ANNALS OF THE RHEUMATIC DISEASES
- IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells
- (2012) S. Vigne et al. BLOOD
- IL-36 in psoriasis
- (2012) JE Towne et al. CURRENT OPINION IN PHARMACOLOGY
- Mutation Analysis of theIL36RNGene in 14 Japanese Patients with Generalized Pustular Psoriasis
- (2012) Muhammad Farooq et al. HUMAN MUTATION
- The Antimicrobial Protein REG3A Regulates Keratinocyte Proliferation and Differentiation after Skin Injury
- (2012) Yuping Lai et al. IMMUNITY
- IL-36γ/IL-1F9, an Innate T-bet Target in Myeloid Cells
- (2012) Malte Bachmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Psoriasiform dermatitis is driven by IL-36–mediated DC-keratinocyte crosstalk
- (2012) Luigi Tortola et al. JOURNAL OF CLINICAL INVESTIGATION
- Interleukin-36 cytokines enhance the production of host defense peptides psoriasin and LL-37 by human keratinocytes through activation of MAPKs and NF-κB
- (2012) Toan The Nguyen et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation
- (2012) Claus-Werner Franzke et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Double-Stranded RNA Analogue Polyinosinic-Polycytidylic Acid Induces Keratinocyte Pyroptosis and Release of IL-36γ
- (2012) Li-Hua Lian et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-36α Exerts Pro-Inflammatory Effects in the Lungs of Mice
- (2012) Ravisankar A. Ramadas et al. PLoS One
- IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist
- (2012) F. L. van de Veerdonk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in IL36RN/IL1F5 Are Associated with the Severe Episodic Inflammatory Skin Disease Known as Generalized Pustular Psoriasis
- (2011) Alexandros Onoufriadis et al. AMERICAN JOURNAL OF HUMAN GENETICS
- IL-36R ligands are potent regulators of dendritic and T cells
- (2011) S. Vigne et al. BLOOD
- Expression of IL-1Rrp2 by human myelomonocytic cells is unique to DCs and facilitates DC maturation by IL-1F8 and IL-1F9
- (2011) Shilla Mutamba et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Interleukin-36 (IL-36) Ligands Require Processing for Full Agonist (IL-36α, IL-36β, and IL-36γ) or Antagonist (IL-36Ra) Activity
- (2011) Jennifer E. Towne et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression
- (2011) A. Johnston et al. JOURNAL OF IMMUNOLOGY
- Inter-Regulation of Th17 Cytokines and the IL-36 Cytokines In Vitro and In Vivo: Implications in Psoriasis Pathogenesis
- (2011) Yijun Carrier et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis
- (2011) Slaheddine Marrakchi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin-1 Family Member 9 Stimulates Chemokine Production and Neutrophil Influx in Mouse Lungs
- (2010) Ravisankar A. Ramadas et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Regulation and Function of the IL-1 Family Cytokine IL-1F9 in Human Bronchial Epithelial Cells
- (2010) Regina T. Chustz et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis
- (2010) Jingxuan Yang et al. JOURNAL OF CELL BIOLOGY
- IL-1RL2 and Its Ligands Contribute to the Cytokine Network in Psoriasis
- (2010) H. Blumberg et al. JOURNAL OF IMMUNOLOGY
- A Subpopulation of CD163-Positive Macrophages Is Classically Activated in Psoriasis
- (2010) Judilyn Fuentes-Duculan et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Local overexpression of interleukin-1 family, member 6 relates to the development of tubulointerstitial lesions
- (2010) Osamu Ichii et al. LABORATORY INVESTIGATION
- Adaptive immune response in osteoclastic bone resorption induced by orally administered Aggregatibacter actinomycetemcomitans in a rat model of periodontal disease
- (2010) Y. Li et al. Molecular Oral Microbiology
- IL-1 family nomenclature
- (2010) Charles Dinarello et al. NATURE IMMUNOLOGY
- Gene Expression Profile of Human Lymphocytes Exposed to211At α Particles
- (2010) A. Turtoi et al. RADIATION RESEARCH
- Differential expression of immunoregulatory genes in monocytes in response toPorphyromonas gingivalisandEscherichia colilipopolysaccharide
- (2009) H. E. Barksby et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma
- (2009) Y A Bochkov et al. Mucosal Immunology
- Psoriasis Is Characterized by Accumulation of Immunostimulatory and Th1/Th17 Cell-Polarizing Myeloid Dendritic Cells
- (2008) Lisa C. Zaba et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8
- (2008) Ceire Costelloe et al. JOURNAL OF NEUROCHEMISTRY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started