IL-36γ/IL-1F9, an Innate T-bet Target in Myeloid Cells

Macrophage Polarization in Bacterial Infections

(2014) M. Benoit et al.   JOURNAL OF IMMUNOLOGY

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells

(2012) S. Vigne et al.   BLOOD

IL-36 in psoriasis

(2012) JE Towne et al.   CURRENT OPINION IN PHARMACOLOGY

Psoriasiform dermatitis is driven by IL-36–mediated DC-keratinocyte crosstalk

(2012) Luigi Tortola et al.   JOURNAL OF CLINICAL INVESTIGATION

The Double-Stranded RNA Analogue Polyinosinic-Polycytidylic Acid Induces Keratinocyte Pyroptosis and Release of IL-36γ

(2012) Li-Hua Lian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist

(2012) F. L. van de Veerdonk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

IL-36R ligands are potent regulators of dendritic and T cells

(2011) S. Vigne et al.   BLOOD

Expression of interleukin (IL)-1 family members upon stimulation with IL-17 differs in keratinocytes derived from patients with psoriasis and healthy donors

(2011) P. Muhr et al.   BRITISH JOURNAL OF DERMATOLOGY

Expression of IL-1Rrp2 by human myelomonocytic cells is unique to DCs and facilitates DC maturation by IL-1F8 and IL-1F9

(2011) Shilla Mutamba et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T-helper cell type-1 transcription factor T-bet is upregulated in pulmonary sarcoidosis

(2011) E. Kriegova et al.   EUROPEAN RESPIRATORY JOURNAL

Interleukin-36 (IL-36) Ligands Require Processing for Full Agonist (IL-36α, IL-36β, and IL-36γ) or Antagonist (IL-36Ra) Activity

(2011) Jennifer E. Towne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression

(2011) A. Johnston et al.   JOURNAL OF IMMUNOLOGY

The Bidirectional Crosstalk between Human Dendritic Cells and Natural Killer Cells

(2011) Rebekka Wehner et al.   Journal of Innate Immunity

Inter-Regulation of Th17 Cytokines and the IL-36 Cytokines In Vitro and In Vivo: Implications in Psoriasis Pathogenesis

(2011) Yijun Carrier et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

T-bet in disease

(2011) Vanja Lazarevic et al.   NATURE IMMUNOLOGY

Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis

(2011) Slaheddine Marrakchi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity

(2010) Heiko Mühl et al.   CELLULAR MICROBIOLOGY

IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells

(2010) Maria H. Lexberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transcriptional regulation of the mucosal immune system mediated by T-bet

(2010) N Powell et al.   Mucosal Immunology

IL-1 family nomenclature

(2010) Charles Dinarello et al.   NATURE IMMUNOLOGY

T-bet represses TH17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt

(2010) Vanja Lazarevic et al.   NATURE IMMUNOLOGY

T-bet protects against exacerbation of schistosome egg-induced immunopathology by regulating Th17-mediated inflammation

(2009) Laura I. Rutitzky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ectopic T-bet Expression Licenses Dendritic Cells for IL-12-Independent Priming of Type 1 T Cells In Vitro

(2009) M. W. Lipscomb et al.   JOURNAL OF IMMUNOLOGY

The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

(2009) R. G. Jenner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of IL-18BP regulation in DLD-1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level

(2008) Malte Bachmann et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE