Increased islet antigen–specific regulatory and effector CD4+ T cells in healthy individuals with the type 1 diabetes–protective haplotype

Epitope Stealing as Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes

(2019) Menno van Lummel et al.   DIABETES

Genetics of type 1 diabetes

(2018) Catherine C .Robertson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

CD137+CD154− Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures

(2018) Anna Nowak et al.   Frontiers in Immunology

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

(2018) Marian Rewers et al.   Current Diabetes Reports

A novel and rapid method to quantify Treg mediated suppression of CD4 T cells

(2017) Anna E. Long et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Antigen-Specific T Cell Analysis Reveals That Active Immune Responses to β Cell Antigens Are Focused on a Unique Set of Epitopes

(2017) Junbao Yang et al.   JOURNAL OF IMMUNOLOGY

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells

(2017) Joshua D. Ooi et al.   NATURE

Genetics of type 1 diabetes

(2017) Maria J Redondo et al.   PEDIATRIC DIABETES

Protective major histocompatibility complex allele prevents type 1 diabetes by shaping the intestinal microbiota early in ontogeny

(2017) Michael Silverman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding Autoimmune Diabetes through the Prism of the Tri-Molecular Complex

(2017) Matthew L. Bettini et al.   Frontiers in Endocrinology

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans

(2016) Petra Bacher et al.   CELL

Regulatory mechanisms of immune tolerance in type 1 diabetes and their failures

(2016) Chantal Kuhn et al.   JOURNAL OF AUTOIMMUNITY

Environmental risk factors for type 1 diabetes

(2016) Marian Rewers et al.   LANCET

Genetic risk factors for type 1 diabetes

(2016) Flemming Pociot et al.   LANCET

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes

(2016) Jenny Aurielle B Babon et al.   NATURE MEDICINE

Viruses in type 1 diabetes

(2016) Heikki Hyöty   PEDIATRIC DIABETES

Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining

(2016) Hannes Uchtenhagen et al.   Nature Communications

Helios Should Not Be Cited as a Marker of Human Thymus-Derived Tregs. Commentary: Helios+ and Helios− Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans

(2016) Eyad Elkord   Frontiers in Immunology

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes

(2015) Jennie H.M. Yang et al.   DIABETES

Coexpression of TIGIT and FCRL3 Identifies Helios+Human Memory Regulatory T Cells

(2015) Khalid Bin Dhuban et al.   JOURNAL OF IMMUNOLOGY

Stable inhibitory activity of regulatory T cells requires the transcription factor Helios

(2015) H.-J. Kim et al.   SCIENCE

Type 1 diabetes immunotherapy using polyclonal regulatory T cells

(2015) Jeffrey A. Bluestone et al.   Science Translational Medicine

Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+T Cells Infiltrate Islets in Type 1 Diabetes

(2014) Vimukthi Pathiraja et al.   DIABETES

tTregs, pTregs, and iTregs: similarities and differences

(2014) Ethan M. Shevach et al.   IMMUNOLOGICAL REVIEWS

The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells

(2014) A. Schneider et al.   JOURNAL OF IMMUNOLOGY

Short- and Long-Term Effects of the Modified Swedish Version of the Active Communication Education (ACE) Program for Adults with Hearing Loss

(2014) Marie Öberg et al.   Journal of the American Academy of Audiology

Assessment of CD4+ T Cell Responses to Glutamic Acid Decarboxylase 65 Using DQ8 Tetramers Reveals a Pathogenic Role of GAD65 121–140 and GAD65 250–266 in T1D Development

(2014) I-Ting Chow et al.   PLoS One

Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes

(2014) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antigen Targets of Type 1 Diabetes Autoimmunity

(2013) B. O. Roep et al.   Cold Spring Harbor Perspectives in Medicine

MHC Class II Polymorphisms, Autoreactive T-Cells, and Autoimmunity

(2013) Sue Tsai et al.   Frontiers in Immunology

CD4+T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring

(2012) Junbao Yang et al.   IMMUNOLOGY

Functional consequences of HLA-DQ8 homozygosity versus heterozygosity for islet autoimmunity in type 1 diabetes

(2011) P Eerligh et al.   GENES AND IMMUNITY

T-cell receptor affinity in thymic development

(2011) Amy E. Moran et al.   IMMUNOLOGY

Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope

(2011) Carolin Daniel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of CD4+ T cells specific for glutamic acid decarboxylase (GAD65) and proinsulin in a patient with stiff-person syndrome but without type 1 diabetes

(2010) Arno Hänninen et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity

(2010) Kenji Yoshida et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

Novel antigens in type 1 diabetes: The importance of ZnT8

(2009) Janet M. Wenzlau et al.   Current Diabetes Reports

Insulin as an autoantigen in NOD/human diabetes

(2008) Li Zhang et al.   CURRENT OPINION IN IMMUNOLOGY

HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk: Analysis of the Type 1 Diabetes Genetics Consortium Families

(2008) H. Erlich et al.   DIABETES