Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope

A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC

(2011) Dhruv K. Sethi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T cell receptor recognition of self and foreign antigens in the induction of autoimmunity

(2011) Kai W. Wucherpfennig et al.   SEMINARS IN IMMUNOLOGY

TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo

(2010) Rachel A. Gottschalk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors: Figure 1.

(2010) Matthias Merkenschlager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Enhancement of antigen-specific Treg vaccination in vivo

(2010) C. Daniel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register

(2010) B. D. Stadinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stability of the Regulatory T Cell Lineage in Vivo

(2010) Y. P. Rubtsov et al.   SCIENCE

Murine High Specificity/Sensitivity Competitive Europium Insulin Autoantibody Assay

(2009) Naru Babaya et al.   Diabetes Technology & Therapeutics

Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy

(2009) Tihamer Orban et al.   JOURNAL OF AUTOIMMUNITY

Cutting Edge: TCR Stimulation Is Sufficient for Induction of Foxp3 Expression in the Absence of DNA Methyltransferase 1

(2009) S. Z. Josefowicz et al.   JOURNAL OF IMMUNOLOGY

A protocol for islet isolation from mouse pancreas

(2009) Dong-Sheng Li et al.   Nature Protocols

DNA methylation controls Foxp3 gene expression

(2008) Julia K. Polansky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis

(2008) Benno Weigmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction of antigen-specific regulatory T cells in wild-type mice: Visualization and targets of suppression

(2008) P. Verginis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR

(2008) S. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity?

(2007) Anish Suri et al.   CURRENT OPINION IN IMMUNOLOGY