T-cell receptor affinity in thymic development

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Why CD8+ T Cells Need Diversity When Growing Up

(2010) Kristin A. Hogquist et al.   IMMUNITY

Transforming Growth Factor-β Signaling Curbs Thymic Negative Selection Promoting Regulatory T Cell Development

(2010) Weiming Ouyang et al.   IMMUNITY

Thymoproteasome Shapes Immunocompetent Repertoire of CD8+ T Cells

(2010) Takeshi Nitta et al.   IMMUNITY

Lysosomal α-Galactosidase Controls the Generation of Self Lipid Antigens for Natural Killer T Cells

(2010) Alexandre Darmoise et al.   IMMUNITY

Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes

(2010) Gerald Wirnsberger et al.   IMMUNOLOGY AND CELL BIOLOGY

Raising the NKT cell family

(2010) Dale I Godfrey et al.   NATURE IMMUNOLOGY

A Novel TCR Transgenic Model Reveals That Negative Selection Involves an Immediate, Bim-Dependent Pathway and a Delayed, Bim-Independent Pathway

(2010) Damian Kovalovsky et al.   PLoS One

Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells

(2009) Jayajit Das et al.   CELL

Thymus-specific serine protease regulates positive selection of a subset of CD4+thymocytes

(2009) Julien Gommeaux et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TCR-dependent differentiation of thymic Foxp3+cells is limited to small clonal sizes

(2009) Monica W.L. Leung et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bim-Mediated Apoptosis Is Not Necessary for Thymic Negative Selection to Ubiquitous Self-Antigens

(2009) Q. Hu et al.   JOURNAL OF IMMUNOLOGY

An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells

(2009) Wan-Lin Lo et al.   NATURE IMMUNOLOGY

An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a

(2009) Peter J R Ebert et al.   NATURE IMMUNOLOGY

Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation

(2009) Benjamin R Marks et al.   NATURE IMMUNOLOGY

Intraclonal competition limits the fate determination of regulatory T cells in the thymus

(2009) Jhoanne L Bautista et al.   NATURE IMMUNOLOGY

Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire

(2009) H. H. Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-affinity peptides and T-cell selection

(2009) Andreas Ziegler et al.   TRENDS IN IMMUNOLOGY

T cell receptor–instructed αβ versus γδ lineage commitment revealed by single-cell analysis

(2008) Taras Kreslavsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The making of NKT cells

(2008) Laurent Gapin   NATURE IMMUNOLOGY