RGMa mediates reactive astrogliosis and glial scar formation through TGFβ1/Smad2/3 signaling after stroke

RGMs: Structural Insights, Molecular Regulation, and Downstream Signaling

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Knockdown of apoptosis signal-regulating kinase 1 affects ischaemia-induced astrocyte activation and glial scar formation

(2016) So Yeong Cheon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke

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TLR3 ligand Poly IC Attenuates Reactive Astrogliosis and Improves Recovery of Rats after Focal Cerebral Ischemia

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Transforming growth factor β-induced expression of chondroitin sulfate proteoglycans is mediated through non-Smad signaling pathways

(2015) Naima Jahan et al.   EXPERIMENTAL NEUROLOGY

Overexpression of Fibulin-5 Attenuates Ischemia/Reperfusion Injury After Middle Cerebral Artery Occlusion in Rats

(2015) Jia Guo et al.   MOLECULAR NEUROBIOLOGY

Attenuated Reactive Gliosis and Enhanced Functional Recovery Following Spinal Cord Injury in Null Mutant Mice of Platelet-Activating Factor Receptor

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Nuclear pore complex remodeling by p75NTR cleavage controls TGF-β signaling and astrocyte functions

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Functional regeneration beyond the glial scar

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Beneficial effects of gfap/vimentin reactive astrocytes for axonal remodeling and motor behavioral recovery in mice after stroke

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Targeted inhibition of KCa3.1 attenuates TGF-β-induced reactive astrogliosis through the Smad2/3 signaling pathway

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Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

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Astrocyte Reactivity and Reactive Astrogliosis: Costs and Benefits

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Modifying Lipid Rafts Promotes Regeneration and Functional Recovery

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Repulsive Guidance Molecule-a Is Involved in Th17-Cell-Induced Neurodegeneration in Autoimmune Encephalomyelitis

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Delayed treatment with chondroitinase ABC promotes sensorimotor recovery and plasticity after stroke in aged rats

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SKI-1 and Furin Generate Multiple RGMa Fragments that Regulate Axonal Growth

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Scar-mediated inhibition and CSPG receptors in the CNS

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RNA interference against repulsive guidance molecule A improves axon sprout and neural function recovery of rats after MCAO/reperfusion

(2012) Jinzhou Feng et al.   EXPERIMENTAL NEUROLOGY

Transforming growth factor β1-induced astrocyte migration is mediated in part by activating 5-lipoxygenase and cysteinyl leukotriene receptor 1

(2012) Xue-Qin Huang et al.   Journal of Neuroinflammation

Novel Roles of the Chemorepellent Axon Guidance Molecule RGMa in Cell Migration and Adhesion

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CRMP-2 Is Involved in Axon Growth Inhibition Induced by RGMa In Vitro and In Vivo

(2012) Tianzhu Wang et al.   MOLECULAR NEUROBIOLOGY

Accumulation of a repulsive axonal guidance molecule RGMa in amyloid plaques: a possible hallmark of regenerative failure in Alzheimer's disease brains

(2012) J. Satoh et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

TGF-β/TGF-β receptor system and its role in physiological and pathological conditions

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Smad proteins differentially regulate transforming growth factor-β-mediated induction of chondroitin sulfate proteoglycans

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RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis

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Activated Microglia Inhibit Axonal Growth through RGMa

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TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke

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Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways

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Fibrinogen Triggers Astrocyte Scar Formation by Promoting the Availability of Active TGF-  after Vascular Damage

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The repulsive guidance molecule, RGMa, promotes retinal ganglion cell survival in vitro and in vivo

(2010) P.D. Koeberle et al.   NEUROSCIENCE

Inactivation of Ras by p120GAP via Focal Adhesion Kinase Dephosphorylation Mediates RGMa-Induced Growth Cone Collapse

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Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Non-Smad pathways in TGF-β signaling

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Chondroitin-4-sulfation negatively regulates axonal guidance and growth

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