The roles and implications of exosomes in sarcoma

Detection and isolation of circulating exosomes and microvesicles for cancer monitoring and diagnostics using micro-/nano-based devices

(2016) Jina Ko et al.   ANALYST

TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site

(2016) L. Rivoltini et al.   CLINICAL CANCER RESEARCH

Extracellular vesicle isolation and characterization: toward clinical application

(2016) Rong Xu et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomic analysis of exosomal cargo: the challenge of high purity vesicle isolation

(2016) Agata Abramowicz et al.   Molecular BioSystems

Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells

(2016) Myung Soo Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Exosomal miRNAs as biomarkers of recurrent lung cancer

(2016) Radha Munagala et al.   TUMOR BIOLOGY

Enterovirus 71 transmission by exosomes establishes a productive infection in human neuroblastoma cells

(2016) Lingxiang Mao et al.   VIRUS GENES

Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes

(2016) Claudia Berrondo et al.   PLoS One

Effective internalization of U251-MG-secreted exosomes into cancer cells and characterization of their lipid components

(2015) Yuki Toda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

(2015) Anoek Zomer et al.   CELL

Analytical challenges of extracellular vesicle detection: A comparison of different techniques

(2015) Uta Erdbrügger et al.   CYTOMETRY PART A

microRNA-143 is associated with the survival of ALDH1+CD133+ osteosarcoma cells and the chemoresistance of osteosarcoma

(2015) Jiahui Zhou et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Vps4A functions as a tumor suppressor by regulating the secretion and uptake of exosomal microRNAs in human hepatoma cells

(2015) Jin-xing Wei et al.   HEPATOLOGY

Using exosomes, naturally-equipped nanocarriers, for drug delivery

(2015) Elena V. Batrakova et al.   JOURNAL OF CONTROLLED RELEASE

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

(2015) Sonia A. Melo et al.   NATURE

Targeted Chemotherapy in Bone and Soft-Tissue Sarcoma

(2015) Jared L. Harwood et al.   ORTHOPEDIC CLINICS OF NORTH AMERICA

Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis

(2015) Liliana Endo-Munoz et al.   PLoS One

Effects of methotrexate and salazosulfapyridine on protein profiles of exosomes derived from a human synovial sarcoma cell line of SW982

(2015) Hirotaka Tsuno et al.   Proteomics Clinical Applications

Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes

(2015) Valentina R. Minciacchi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

(2015) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles

(2015) Valentina R. Minciacchi et al.   Oncotarget

Regulated lysosomal exocytosis mediates cancer progression

(2015) E. Machado et al.   Science Advances

17β-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells

(2015) Paul K. Wright et al.   Oncotarget

Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma

(2015) Shu-biao Ye et al.   Oncotarget

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration

(2014) Keisuke Shimbo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular characterization of exosome-like vesicles from breast cancer cells

(2014) Stefan Kruger et al.   BMC CANCER

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration

(2014) Liang Ma et al.   CELL RESEARCH

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Tumor-derived exosomes in oncogenic reprogramming and cancer progression

(2014) Sarmad N. Saleem et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

ATP13A2/PARK9 Regulates Secretion of Exosomes and  -Synuclein

(2014) T. Tsunemi et al.   JOURNAL OF NEUROSCIENCE

RETRACTED: β-Elemene against human lung cancer via up-regulation of P53 protein expression to promote the release of exosome

(2014) Jianying Li et al.   LUNG CANCER

Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer

(2014) Kenji Takahashi et al.   FEBS Open Bio

Nucleic acids in exosomes: Disease markers and intercellular communication molecules

(2013) O. N. Gusachenko et al.   BIOCHEMISTRY-MOSCOW

First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications

(2013) Isabella V. Miller et al.   BIOLOGY OF THE CELL

Heparanase Regulates Secretion, Composition, and Function of Tumor Cell-derived Exosomes

(2013) Camilla A. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

(2013) Johnny C. Akers et al.   JOURNAL OF NEURO-ONCOLOGY

Characterization and proteomic analysis of ovarian cancer-derived exosomes

(2013) Bing Liang et al.   Journal of Proteomics

Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion

(2013) S. Atay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The therapeutic potential of mesenchymal stem cell-derived extracellular vesicles

(2013) Takeshi Katsuda et al.   PROTEOMICS

Exosomes as nucleic acid nanocarriers

(2012) Jasper G. van den Boorn et al.   ADVANCED DRUG DELIVERY REVIEWS

Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease

(2012) Dolores Di Vizio et al.   AMERICAN JOURNAL OF PATHOLOGY

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes

(2012) Jessica Wahlgren et al.   NUCLEIC ACIDS RESEARCH

Interaction and uptake of exosomes by ovarian cancer cells

(2011) Cristina Escrevente et al.   BMC CANCER

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Analysis of exosome release and its prognostic value in human colorectal cancer

(2011) J. Silva et al.   GENES CHROMOSOMES & CANCER

Antigen Localization Controls T Cell-Mediated Tumor Immunity

(2011) I. S. Zeelenberg et al.   JOURNAL OF IMMUNOLOGY

Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice

(2011) Lilla Turiák et al.   Journal of Proteomics

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

ExoCarta 2012: database of exosomal proteins, RNA and lipids

(2011) S. Mathivanan et al.   NUCLEIC ACIDS RESEARCH

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy

(2010) Tian Tian et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

(2010) Dongmei Sun et al.   MOLECULAR THERAPY

Cellular Internalization of Exosomes Occurs Through Phagocytosis

(2010) Du Feng et al.   TRAFFIC

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

(2009) Guilherme Rabinowits et al.   Clinical Lung Cancer

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

(2009) Vandhana Muralidharan-Chari et al.   CURRENT BIOLOGY

Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses

(2008) I. S. Zeelenberg et al.   CANCER RESEARCH

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY

Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes

(2008) Juha Hakulinen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Second and Subsequent Recurrences of Osteosarcoma: Presentation, Treatment, and Outcomes of 249 Consecutive Cooperative Osteosarcoma Study Group Patients

(2008) Stefan S. Bielack et al.   JOURNAL OF CLINICAL ONCOLOGY