Calycosin ameliorates doxorubicin‐induced cardiotoxicity by suppressing oxidative stress and inflammation via the sirtuin 1–NOD‐like receptor protein 3 pathway

Calycosin alleviates cerulein-induced acute pancreatitis by inhibiting the inflammatory response and oxidative stress via the p38 MAPK and NF-κB signal pathways in mice

(2018) Ran Ma et al.   BIOMEDICINE & PHARMACOTHERAPY

Negative regulation of NLRP3 inflammasome by SIRT1 in vascular endothelial cells

(2017) Yanxiang Li et al.   IMMUNOBIOLOGY

Calycosin inhibits oxidative stress-induced cardiomyocyte apoptosis via activating estrogen receptor-α/β

(2016) Bin Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hydrogen sulfide protects H9c2 cardiac cells against doxorubicin-induced cytotoxicity through the PI3K/Akt/FoxO3a pathway

(2016) MI-HUA LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Docosahexaenoic Acid Attenuates Doxorubicin-induced Cytotoxicity and Inflammation by Suppressing NF-κB/iNOS/NO Signaling Pathway Activation in H9C2 Cardiac Cells

(2016) Zhi-Quan Wang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

The Protective Role of Phenolic Compounds Against Doxorubicin-induced Cardiotoxicity: A Comprehensive Review

(2016) Kamal Razavi-Azarkhiavi et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

NLRP3 Deficiency Reduces Macrophage Interleukin-10 Production and Enhances the Susceptibility to Doxorubicin-induced Cardiotoxicity

(2016) Motoi Kobayashi et al.   Scientific Reports

Calycosin and Genistein Induce Apoptosis by Inactivation of HOTAIR/p-Akt Signaling Pathway in Human Breast Cancer MCF-7 Cells

(2015) Jian Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

SIRT1 activation rescues doxorubicin-induced loss of functional competence of human cardiac progenitor cells

(2015) Antonella De Angelis et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Pharmacologic Inhibition of the NLRP3 Inflammasome Preserves Cardiac Function After Ischemic and Nonischemic Injury in the Mouse

(2015) Carlo Marchetti et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Chrysin alleviates acute doxorubicin cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis

(2014) Eman M. Mantawy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

NLRP3 Deficiency Ameliorates Neurovascular Damage in Experimental Ischemic Stroke

(2014) Fan Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pharmaceutical properties of calycosin, the major bioactive isoflavonoid in the dry root extract ofRadix astragali

(2014) JunQing Gao et al.   PHARMACEUTICAL BIOLOGY

Protective Effects of Calycosin Against CCl4-Induced Liver Injury with Activation of FXR and STAT3 in Mice

(2014) Xinli Chen et al.   PHARMACEUTICAL RESEARCH

Calycosin Suppresses Breast Cancer Cell Growth via ERβ-Dependent Regulation of IGF-1R, p38 MAPK and PI3K/Akt Pathways

(2014) Jian Chen et al.   PLoS One

Calycosin Induces Apoptosis by Upregulation of RASD1 in Human Breast Cancer Cells MCF-7

(2013) J. Tian et al.   HORMONE AND METABOLIC RESEARCH

Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation

(2013) Pieter J. Bakker et al.   KIDNEY INTERNATIONAL

Identification of Multiple Ingredients for a Traditional Chinese Medicine Preparation (Bu-yang-huan-wu-tang) by Liquid Chromatography Coupled with Tandem Mass Spectrometry

(2013) Lee-Hsin Shaw et al.   MOLECULES

Seven sirtuins for seven deadly diseases ofaging

(2012) Brian J. Morris   FREE RADICAL BIOLOGY AND MEDICINE

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

Calycosin promotes proliferation of estrogen receptor-positive cells via estrogen receptors and ERK1/2 activation in vitro and in vivo

(2011) Jian Chen et al.   CANCER LETTERS

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

(2011) C. Zhang et al.   CARDIOVASCULAR RESEARCH

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY