Calycosin Suppresses Breast Cancer Cell Growth via ERβ-Dependent Regulation of IGF-1R, p38 MAPK and PI3K/Akt Pathways

A phase I trial of the IGF-1R antibody Cixutumumab in combination with temsirolimus in patients with metastatic breast cancer

(2013) Cynthia X. Ma et al.   BREAST CANCER RESEARCH AND TREATMENT

PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis

(2013) Marie-France Langelier et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Resveratrol regulates the cell viability promoted by 17β-estradiol or bisphenol A via down-regulation of the cross-talk between estrogen receptor α and insulin growth factor-1 receptor in BG-1 ovarian cancer cells

(2013) Nam-Hee Kang et al.   FOOD AND CHEMICAL TOXICOLOGY

Calycosin Induces Apoptosis by Upregulation of RASD1 in Human Breast Cancer Cells MCF-7

(2013) J. Tian et al.   HORMONE AND METABOLIC RESEARCH

Differential Ligand Binding Affinities of Human Estrogen Receptor-α Isoforms

(2013) Amanda H. Y. Lin et al.   PLoS One

Interaction between IGF-IR and ER Induced by E2 and IGF-I

(2013) Zhenghong Yu et al.   PLoS One

Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors α- and β-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft

(2013) Ruchi Saxena et al.   STEROIDS

Phytoestrogens in menopausal supplements induce ER-dependent cell proliferation and overcome breast cancer treatment in an in vitro breast cancer model

(2013) Majorie B.M. van Duursen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Estrogen and Cancer

(2012) Jing Liang et al.   Annual Review of Physiology

Estrogen receptor signaling as a target for novel breast cancer therapeutics

(2012) Jack-Michel Renoir et al.   BIOCHEMICAL PHARMACOLOGY

A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein

(2012) Chi Tze Tiong et al.   CARCINOGENESIS

New advances on the functional cross-talk between insulin-like growth factor-I and estrogen signaling in cancer

(2012) Viviana Bartella et al.   CELLULAR SIGNALLING

Insulin and its analogues and their affinities for the IGF1 receptor

(2012) Aimee J Varewijck et al.   ENDOCRINE-RELATED CANCER

Estrogen upregulates the IGF-1 signaling pathway in lung cancer through estrogen receptor-β

(2012) Hexiao Tang et al.   MEDICAL ONCOLOGY

Celecoxib inhibits growth of human autosomal dominant polycystic kidney cyst-lining epithelial cells through the VEGF/Raf/MAPK/ERK signaling pathway

(2012) Tao Xu et al.   MOLECULAR BIOLOGY REPORTS

Estrogen receptor beta growth-inhibitory effects are repressed through activation of MAPK and PI3K signalling in mammary epithelial and breast cancer cells

(2012) C Z Cotrim et al.   ONCOGENE

Estradiol receptors in breast cancer cells: Associated co-factors as targets for new therapeutic approaches

(2012) Jack-Michel Renoir   STEROIDS

Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation

(2011) Oli MV Grober et al.   BMC GENOMICS

Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells

(2011) Yong Zhao et al.   CANCER LETTERS

Formononetin Induces Cell Cycle Arrest of Human Breast Cancer Cells via IGF1/PI3K/Akt Pathways In Vitro and In Vivo

(2011) J. Chen et al.   HORMONE AND METABOLIC RESEARCH

The Life and Death of Breast Cancer Cells: Proposing a Role for the Effects of Phytoestrogens on Potassium Channels

(2011) Joanne L. Wallace et al.   JOURNAL OF MEMBRANE BIOLOGY

Effect of ligand-activated estrogen receptor β on lymphoma growth in vitro and in vivo

(2011) K Yakimchuk et al.   LEUKEMIA

Antitumor Activity of GSK1904529A, a Small-molecule Inhibitor of the Insulin-like Growth Factor-I Receptor Tyrosine Kinase

(2009) P. Sabbatini et al.   CLINICAL CANCER RESEARCH

Crosstalk Between Epidermal Growth Factor Receptor- and Insulin-Like Growth Factor-1 Receptor Signaling: Implications for Cancer Therapy

(2009) J. Veeken et al.   CURRENT CANCER DRUG TARGETS

The mitochondrial death pathway: a promising therapeutic target in diseases

(2009) Sanjeev Gupta et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Differential Expression of IGF-I and Insulin Receptor Isoforms in HPV Positive and Negative Human Cervical Cancer Cell Lines

(2008) M.-L. Serrano et al.   HORMONE AND METABOLIC RESEARCH

Crosstalk Between IGF1R and Estrogen Receptor Signaling in Breast Cancer

(2008) Dedra H. Fagan et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA