NLRP3 Deficiency Reduces Macrophage Interleukin-10 Production and Enhances the Susceptibility to Doxorubicin-induced Cardiotoxicity

Monocyte and macrophage contributions to cardiac remodeling

(2016) Maarten Hulsmans et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pharmacologic Inhibition of the NLRP3 Inflammasome Preserves Cardiac Function After Ischemic and Nonischemic Injury in the Mouse

(2015) Carlo Marchetti et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

(2015) Mélanie Bruchard et al.   NATURE IMMUNOLOGY

Bruton’s tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury

(2015) Minako Ito et al.   Nature Communications

Cardioprotective function of cardiac macrophages

(2014) K. Fujiu et al.   CARDIOVASCULAR RESEARCH

NLRP3 Inflammasome as a Novel Player in Myocardial Infarction

(2014) Masafumi Takahashi   International Heart Journal

NLRP3 Protein Deficiency Exacerbates Hyperoxia-induced Lethality through Stat3 Protein Signaling Independent of Interleukin-1β

(2014) Yoshiko Mizushina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia-Reperfusion Injury Independently of Inflammasomes

(2014) Y. Inoue et al.   JOURNAL OF IMMUNOLOGY

Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice

(2012) Fumitake Usui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophages and fibrosis: How resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair

(2012) Maciej Lech et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Interleukin-10 Treatment Attenuates Pressure Overload–Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3–Dependent Inhibition of Nuclear Factor-κB

(2012) Suresh Kumar Verma et al.   CIRCULATION

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome

(2011) Kristin A. D. Sauter et al.   CANCER BIOLOGY & THERAPY

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

(2011) Masanori Kawaguchi et al.   CIRCULATION

Recombinant human interleukin-1 receptor antagonist protects mice against acute doxorubicin-induced cardiotoxicity

(2010) Jinzhou Zhu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

An Inflammasome-Independent Role for Epithelial-Expressed Nlrp3 in Renal Ischemia-Reperfusion Injury

(2010) A. A. Shigeoka et al.   JOURNAL OF IMMUNOLOGY

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF CELL BIOLOGY

Critical Role of Bone Marrow Apoptosis-Associated Speck-Like Protein, an Inflammasome Adaptor Molecule, in Neointimal Formation After Vascular Injury in Mice

(2008) Noriyuki Yajima et al.   CIRCULATION

IL-10 Inhibits Inflammation and Attenuates Left Ventricular Remodeling After Myocardial Infarction via Activation of STAT3 and Suppression of HuR

(2008) Prasanna Krishnamurthy et al.   CIRCULATION RESEARCH

Interleukin-10 improves left ventricular function in rats with heart failure subsequent to myocardial infarction

(2008) Christian Stumpf et al.   EUROPEAN JOURNAL OF HEART FAILURE

Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice

(2008) Alexander Riad et al.   EUROPEAN JOURNAL OF HEART FAILURE

Strain differences regarding susceptibility to ursolic acid-induced interleukin-1β release in murine macrophages

(2008) Yasutaka Ikeda et al.   LIFE SCIENCES