Genistein protects against amyloid‐beta‐induced toxicity in SH‐SY5Y cells by regulation of Akt and Tau phosphorylation

Genistein Inhibits Aβ25–35-Induced Neuronal Death with Changes in the Electrophysiological Properties of Voltage-Gated Sodium and Potassium Channels

(2019) Yu-xiang Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Role of Plant-Derived Flavonoids and Their Mechanism in Attenuation of Alzheimer’s and Parkinson’s Diseases: An Update of Recent Data

(2018) Ghulam Hussain et al.   MOLECULES

Direct pharmacological Akt activation rescues Alzheimer's disease like memory impairments and aberrant synaptic plasticity

(2018) Jee Hyun Yi et al.   NEUROPHARMACOLOGY

Human Ischaemic Cascade Studies Using SH-SY5Y Cells: a Systematic Review and Meta-Analysis

(2018) Ye Liu et al.   Translational Stroke Research

Genistein inhibits Aβ25-35 -induced SH-SY5Y cell damage by modulating the expression of apoptosis-related proteins and Ca2+ influx through ionotropic glutamate receptors

(2018) Hui-nan Xu et al.   PHYTOTHERAPY RESEARCH

Phytochemical Ginkgolide B Attenuates Amyloid-β1-42 Induced Oxidative Damage and Altered Cellular Responses in Human Neuroblastoma SH-SY5Y Cells

(2017) Iqbal Gill et al.   JOURNAL OF ALZHEIMERS DISEASE

The SH-SY5Y cell line in Parkinson’s disease research: a systematic review

(2017) Helena Xicoy et al.   Molecular Neurodegeneration

Genistein protects hippocampal neurons against injury by regulating calcium/calmodulin dependent protein kinase IV protein levels in Alzheimer's disease model rats

(2017) Biao Cai et al.   Neural Regeneration Research

Treatment with the neurotoxic Aβ (25–35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells

(2016) Francesca Lattanzio et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Evidence for genistein as a mitochondriotropic molecule

(2016) Marcos Roberto de Oliveira   MITOCHONDRION

Changes in Cell Cycle and Up-Regulation of Neuronal Markers During SH-SY5Y Neurodifferentiation by Retinoic Acid are Mediated by Reactive Species Production and Oxidative Stress

(2016) Alice Kunzler et al.   MOLECULAR NEUROBIOLOGY

Molecular and Therapeutic Targets of Genistein in Alzheimer’s Disease

(2016) Kasi Pandima Devi et al.   MOLECULAR NEUROBIOLOGY

Genistein suppresses the mitochondrial apoptotic pathway in hippocampal neurons in rats with Alzheimer's disease

(2016) Biao Cai et al.   Neural Regeneration Research

Impact of Plant-Derived Flavonoids on Neurodegenerative Diseases

(2016) Silvia Lima Costa et al.   NEUROTOXICITY RESEARCH

Are Polyphenols Strong Dietary Agents Against Neurotoxicity and Neurodegeneration?

(2016) Susana Almeida et al.   NEUROTOXICITY RESEARCH

Roles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment

(2015) Giulio Maria Pasinetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Genistein Inhibits Aβ25–35-Induced Synaptic Toxicity and Regulates CaMKII/CREB Pathway in SH-SY5Y Cells

(2015) Yuan-Di Xi et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Analysis of the amyloid precursor protein role in neuritogenesis reveals a biphasic SH-SY5Y neuronal cell differentiation model

(2015) Joana Fernandes da Rocha et al.   JOURNAL OF NEUROCHEMISTRY

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

Polyphenols as Therapeutic Molecules in Alzheimer’s Disease Through Modulating Amyloid Pathways

(2014) Johant Lakey-Beitia et al.   MOLECULAR NEUROBIOLOGY

Nutrition and prevention of Alzheimer’s dementia

(2014) Arun Swaminathan et al.   Frontiers in Aging Neuroscience

Nature as a source of metabolites with cholinesterase-inhibitory activity: an approach to Alzheimer's disease treatment

(2013) Brígida R. Pinho et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Neuroprotective Effects of Resveratrol Against Aβ Administration in Rats are Improved by Lipid-Core Nanocapsules

(2013) Rudimar L. Frozza et al.   MOLECULAR NEUROBIOLOGY

Free and nanoencapsulated curcumin suppress β-amyloid-induced cognitive impairments in rats: Involvement of BDNF and Akt/GSK-3β signaling pathway

(2013) Juliana B. Hoppe et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The curry spice curcumin attenuates beta-amyloid-induced toxicity through beta-catenin and PI3K signaling in rat organotypic hippocampal slice culture

(2013) Juliana Bender Hoppe et al.   NEUROLOGICAL RESEARCH

Tau protein kinases: Involvement in Alzheimer's disease

(2012) Ludovic Martin et al.   AGEING RESEARCH REVIEWS

The Potential Use of Hormone-Based Therapeutics for the Treatment of Alzheimers Disease

(2012) Jenna C. Carroll et al.   Current Alzheimer Research

Roles of Glycogen Synthase Kinase 3 in Alzheimer’s Disease

(2012) Zhiyou Cai et al.   Current Alzheimer Research

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology

Genistein inhibits aggregation of exogenous amyloid-beta1–40 and alleviates astrogliosis in the hippocampus of rats

(2011) Maryam Bagheri et al.   BRAIN RESEARCH

Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action

(2011) Fernando Kreutz et al.   NEUROCHEMISTRY INTERNATIONAL

Estrogen therapy and Alzheimer's dementia

(2010) Michael C. Craig et al.   Annals of the New York Academy of Sciences

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

(2010) Fernanda Martins Lopes et al.   BRAIN RESEARCH

Hormonal Influences on Cognition and Risk for Alzheimer’s Disease

(2010) Sarah C. Janicki et al.   Current Neurology and Neuroscience Reports

Genistein as a neuroprotective antioxidant attenuates redox imbalance induced by β-amyloid peptides 25–35 in PC12 cells

(2010) Weiwei Ma et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Genistein ameliorates learning and memory deficits in amyloid β(1–40) rat model of Alzheimer’s disease

(2010) Maryam Bagheri et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oestradiol or genistein rescues neurons from amyloid beta-induced cell death by inhibiting activation of p38

(2009) Soraya L. Vallés et al.   AGING CELL

Estradiol or genistein prevent Alzheimer's disease-associated inflammation correlating with an increase PPARγ expression in cultured astrocytes

(2009) Soraya L. Valles et al.   BRAIN RESEARCH

Neuroprotective effects of genistein and folic acid on apoptosis of rat cultured cortical neurons induced by β-amyloid 31-35

(2009) Huan-Ling Yu et al.   BRITISH JOURNAL OF NUTRITION

Isoflavones Prevent Endoplasmic Reticulum Stress-Mediated Neuronal Degeneration by Inhibiting Tau Hyperphosphorylation in SH-SY5Y Cells

(2009) Youn-Jin Park et al.   JOURNAL OF MEDICINAL FOOD

Alzheimer's disease in women

(2008) Michael C. Craig et al.   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

A Comparative Study of β-Amyloid Peptides Aβ1-42 and Aβ25-35 Toxicity in Organotypic Hippocampal Slice Cultures

(2008) Rudimar Luiz Frozza et al.   NEUROCHEMICAL RESEARCH

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research

(2008) Yuen-Ting Cheung et al.   NEUROTOXICOLOGY