Changes in Cell Cycle and Up-Regulation of Neuronal Markers During SH-SY5Y Neurodifferentiation by Retinoic Acid are Mediated by Reactive Species Production and Oxidative Stress

An In Vitro Model for Neuroscience: Differentiation of SH-SY5Y Cells into Cells with Morphological and Biochemical Characteristics of Mature Neurons

(2017) Lotta Agholme et al.   JOURNAL OF ALZHEIMERS DISEASE

Nrf2 protects mitochondrial decay by oxidative stress

(2016) Joshua Strom et al.   FASEB JOURNAL

Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line

(2015) Stephanie Graser et al.   BONE

Oxytocin Increases Neurite Length and Expression of Cytoskeletal Proteins Associated with Neuronal Growth

(2015) Z. Lestanova et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

NRF2 Mediates Neuroblastoma Proliferation and Resistance to Retinoic Acid Cytotoxicity in a Model of In Vitro Neuronal Differentiation

(2015) Vitor de Miranda Ramos et al.   MOLECULAR NEUROBIOLOGY

Human induced pluripotent stem cells in Parkinson's disease: A novel cell source of cell therapy and disease modeling

(2015) Wen Li et al.   PROGRESS IN NEUROBIOLOGY

Analysis of the Catecholaminergic Phenotype in Human SH-SY5Y and BE(2)-M17 Neuroblastoma Cell Lines upon Differentiation

(2015) Roberta Filograna et al.   PLoS One

Advanced glycation end products induce oxidative stress and mitochondrial dysfunction in SH-SY5Y cells

(2014) Xu Wang et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Gene Expression Profile of NF-κB, Nrf2, Glycolytic, and p53 Pathways During the SH-SY5Y Neuronal Differentiation Mediated by Retinoic Acid

(2014) Matheus Augusto de Bittencourt Pasquali et al.   MOLECULAR NEUROBIOLOGY

Vitamin A (retinol) downregulates the receptor for advanced glycation endproducts (RAGE) by oxidant-dependent activation of p38 MAPK and NF-kB in human lung cancer A549 cells

(2013) Matheus Augusto de Bittencourt Pasquali et al.   CELLULAR SIGNALLING

Phenotypic Characterization of Retinoic Acid Differentiated SH-SY5Y Cells by Transcriptional Profiling

(2013) Joanna A. Korecka et al.   PLoS One

Retinol induces morphological alterations and proliferative focus formation through free radical-mediated activation of multiple signaling pathways

(2012) Daniel Pens Gelain et al.   ACTA PHARMACOLOGICA SINICA

Trolox-Sensitive Reactive Oxygen Species Regulate Mitochondrial Morphology, Oxidative Phosphorylation and Cytosolic Calcium Handling in Healthy Cells

(2012) Felix Distelmaier et al.   ANTIOXIDANTS & REDOX SIGNALING

PI3K/AKT and ERK regulate retinoic acid-induced neuroblastoma cellular differentiation

(2012) Jingbo Qiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cellular models to investigate biochemical pathways in Parkinson’s disease

(2012) Tiziana Alberio et al.   FEBS Journal

Mitochondrial respiratory chain dysfunction: Implications in neurodegeneration

(2012) María Morán et al.   FREE RADICAL BIOLOGY AND MEDICINE

Retinoic acid-induced differentiation increases the rate of oxygen consumption and enhances the spare respiratory capacity of mitochondria in SH-SY5Y cells

(2012) Zhiyin Xun et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress

(2011) Lonnie Schneider et al.   FREE RADICAL BIOLOGY AND MEDICINE

In vitro optimization of retinoic acid–induced neuritogenesis and TH endogenous expression in human SH-SY5Y neuroblastoma cells by the antioxidant Trolox

(2011) Mario Luiz Conte da Frota Junior et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Vitamin A (retinol) up-regulates the receptor for advanced glycation endproducts (RAGE) through p38 and Akt oxidant-dependent activation

(2011) Daniel Pens Gelain et al.   TOXICOLOGY

Redox characterization of usnic acid and its cytotoxic effect on human neuron-like cells (SH-SY5Y)

(2011) Thallita Kelly Rabelo et al.   TOXICOLOGY IN VITRO

PKC delta and NADPH oxidase in retinoic acid-induced neuroblastoma cell differentiation

(2010) Mariapaola Nitti et al.   CELLULAR SIGNALLING

Nrf2 promotes neuronal cell differentiation

(2009) Fei Zhao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Toxic effects of dopamine metabolism in Parkinson's disease

(2009) Nobutaka Hattori et al.   PARKINSONISM & RELATED DISORDERS

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research

(2008) Yuen-Ting Cheung et al.   NEUROTOXICOLOGY

Retinol and retinoic acid modulate catalase activity in Sertoli cells by distinct and gene expression-independent mechanisms

(2008) Matheus A.B. Pasquali et al.   TOXICOLOGY IN VITRO

Retinoic acid induces apoptosis by a non-classical mechanism of ERK1/2 activation

(2008) Alfeu Zanotto-Filho et al.   TOXICOLOGY IN VITRO

Evidence of increased reactive species formation by retinol, but not retinoic acid, in PC12 cells

(2007) Daniel Pens Gelain et al.   TOXICOLOGY IN VITRO