Mechanomicrobiology: how bacteria sense and respond to forces

Flagellar stators stimulate c-di-GMP production by Pseudomonas aeruginosa

(2019) Amy E. Baker et al.   JOURNAL OF BACTERIOLOGY

Pseudomonas aeruginosa orchestrates twitching motility by sequential control of type IV pili movements

(2019) Lorenzo Talà et al.   Nature Microbiology

Bacteria and archaea on Earth and their abundance in biofilms

(2019) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

Functional Regulators of Bacterial Flagella

(2019) Sundharraman Subramanian et al.   Annual Review of Microbiology

Bacterial mechanosensing: the force will be with you, always

(2019) Vernita D. Gordon et al.   JOURNAL OF CELL SCIENCE

Bacterial quorum sensing in complex and dynamically changing environments

(2019) Sampriti Mukherjee et al.   NATURE REVIEWS MICROBIOLOGY

A multiphase theory for spreading microbial swarms and films

(2019) Siddarth Srinivasan et al.   eLife

Mechanical instability and interfacial energy drive biofilm morphogenesis

(2019) Jing Yan et al.   eLife

Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing

(2019) Joseph E. Sanfilippo et al.   Nature Microbiology

Collective intercellular communication through ultra-fast hydrodynamic trigger waves

(2019) Arnold J. T. M. Mathijssen et al.   NATURE

Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation

(2019) Guannan Liu et al.   PHYSICAL REVIEW LETTERS

Vibrio choleraefilamentation promotes chitin surface attachment at the expense of competition in biofilms

(2019) Benjamin R. Wucher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular advective-diffusion drives the emergence of bacterial surface colonization patterns and heterogeneity

(2019) Tamara Rossy et al.   Nature Communications

Diversification of the type IV filament superfamily into machines for adhesion, protein secretion, DNA uptake, and motility

(2019) Rémi Denise et al.   PLOS BIOLOGY

DNA-uptake pili of Vibrio cholerae are required for chitin colonization and capable of kin recognition via sequence-specific self-interaction

(2019) David. W. Adams et al.   Nature Microbiology

Structure and mechanogating of the mammalian tactile channel PIEZO2

(2019) Li Wang et al.   NATURE

Force-induced conformational changes in PIEZO1

(2019) Yi-Chih Lin et al.   NATURE

Surface association sensitizes Pseudomonas aeruginosa to quorum sensing

(2019) Sara K. Chuang et al.   Nature Communications

PilT and PilU are homohexameric ATPases that coordinate to retract type IVa pili

(2019) Jennifer L. Chlebek et al.   PLoS Genetics

Microbial multicellular development: mechanical forces in action

(2018) Natsuko Rivera-Yoshida et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Verticalization of bacterial biofilms

(2018) Farzan Beroz et al.   Nature Physics

Bacterial adhesion at the single-cell level

(2018) Cecile Berne et al.   NATURE REVIEWS MICROBIOLOGY

Staphylococcus aureusclumping factor A is a force-sensitive molecular switch that activates bacterial adhesion

(2018) Philippe Herman-Bausier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multigenerational memory and adaptive adhesion in early bacterial biofilm communities

(2018) Calvin K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The biomass distribution on Earth

(2018) Yinon M. Bar-On et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanism of extreme mechanostability in a pathogen adhesin

(2018) Lukas F. Milles et al.   SCIENCE

Asymmetric adhesion of rod-shaped bacteria controls microcolony morphogenesis

(2018) Marie-Cécilia Duvernoy et al.   Nature Communications

Cell adhesion and fluid flow jointly initiate genotype spatial distribution in biofilms

(2018) Ricardo Martínez-García et al.   PLoS Computational Biology

Retraction of DNA-bound type IV competence pili initiates DNA uptake during natural transformation in Vibrio cholerae

(2018) Courtney K. Ellison et al.   Nature Microbiology

Towards standardized mechanical characterization of microbial biofilms: analysis and critical review

(2018) Héloïse Boudarel et al.   npj Biofilms and Microbiomes

A fluid-to-solid jamming transition underlies vertebrate body axis elongation

(2018) Alessandro Mongera et al.   NATURE

The outer membrane is an essential load-bearing element in Gram-negative bacteria

(2018) Enrique R. Rojas et al.   NATURE

A fluorescent membrane tension probe

(2018) Adai Colom et al.   Nature Chemistry

Mucins and Their Role in Shaping the Functions of Mucus Barriers

(2018) C.E. Wagner et al.   Annual Review of Cell and Developmental Biology

A Surface-Induced Asymmetric Program Promotes Tissue Colonization by Pseudomonas aeruginosa

(2018) Benoît-Joseph Laventie et al.   Cell Host & Microbe

Emergence of three-dimensional order and structure in growing biofilms

(2018) Raimo Hartmann et al.   Nature Physics

Reassessing the role of the Escherichia coli CpxAR system in sensing surface contact

(2018) Tom E. P. Kimkes et al.   PLoS One

Self-induced mechanical stress can trigger biofilm formation in uropathogenic Escherichia coli

(2018) Eric K. Chu et al.   Nature Communications

Spatial arrangement of several flagellins within bacterial flagella improves motility in different environments

(2018) Marco J. Kühn et al.   Nature Communications

Salivary mucins promote the coexistence of competing oral bacterial species

(2017) Erica Shapiro Frenkel et al.   ISME Journal

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

(2017) Caitlin N. Spaulding et al.   NATURE

Mechanobiology of collective cell behaviours

(2017) Benoit Ladoux et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Piezos thrive under pressure: mechanically activated ion channels in health and disease

(2017) Swetha E. Murthy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bacteria exploit a polymorphic instability of the flagellar filament to escape from traps

(2017) Marco J. Kühn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Force generation by groups of migrating bacteria

(2017) Benedikt Sabass et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Voltage-gated calcium flux mediatesEscherichia colimechanosensation

(2017) Giancarlo N. Bruni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanosensing of shear byPseudomonas aeruginosaleads to increased levels of the cyclic-di-GMP signal initiating biofilm development

(2017) Christopher A. Rodesney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catch bond drives stator mechanosensitivity in the bacterial flagellar motor

(2017) Ashley L Nord et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obstruction of pilus retraction stimulates bacterial surface sensing

(2017) Courtney K. Ellison et al.   SCIENCE

Second messenger–mediated tactile response by a bacterial rotary motor

(2017) Isabelle Hug et al.   SCIENCE

Force-Induced Strengthening of the Interaction between Staphylococcus aureus Clumping Factor B and Loricrin

(2017) Pauline Vitry et al.   mBio

Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion

(2017) Jing Yan et al.   Nature Communications

Bow-tie signaling in c-di-GMP: Machine learning in a simple biochemical network

(2017) Jinyuan Yan et al.   PLoS Computational Biology

Flow environment and matrix structure interact to determine spatial competition in Pseudomonas aeruginosa biofilms

(2017) Carey D Nadell et al.   eLife

Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators

(2017) Jutta Nesper et al.   eLife

Probing the internal micromechanical properties of Pseudomonas aeruginosa biofilms by Brillouin imaging

(2017) A. Karampatzakis et al.   npj Biofilms and Microbiomes

Evolutionary adaptations of biofilms infecting cystic fibrosis lungs promote mechanical toughness by adjusting polysaccharide production

(2017) Kristin Kovach et al.   npj Biofilms and Microbiomes

Evolution of Cell Size Homeostasis and Growth Rate Diversity during Initial Surface Colonization of Shewanella oneidensis

(2016) Calvin K. Lee et al.   ACS Nano

Host Selection of Microbiota via Differential Adhesion

(2016) Kirstie McLoughlin et al.   Cell Host & Microbe

Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI

(2016) Cassie Jarvis et al.   ChemMedChem

Sensational biofilms: surface sensing in bacteria

(2016) George A O’Toole et al.   CURRENT OPINION IN MICROBIOLOGY

A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling inPseudomonas aeruginosa

(2016) Yuki F. Inclan et al.   MOLECULAR MICROBIOLOGY

The mechanism of force transmission at bacterial focal adhesion complexes

(2016) Laura M. Faure et al.   NATURE

Self-driven jamming in growing microbial populations

(2016) Morgan Delarue et al.   Nature Physics

Biofilms: an emergent form of bacterial life

(2016) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

The ecology and biogeochemistry of stream biofilms

(2016) Tom J. Battin et al.   NATURE REVIEWS MICROBIOLOGY

Spatial structure, cooperation and competition in biofilms

(2016) Carey D. Nadell et al.   NATURE REVIEWS MICROBIOLOGY

Exposing the Three-Dimensional Biogeography and Metabolic States of Pathogens in Cystic Fibrosis Sputum via Hydrogel Embedding, Clearing, and rRNA Labeling

(2016) William H. DePas et al.   mBio

Optical and force nanoscopy in microbiology

(2016) Jie Xiao et al.   Nature Microbiology

Attached biofilms and suspended aggregates are distinct microbial lifestyles emanating from differing hydraulics

(2016) Robert Niederdorfer et al.   Nature Microbiology

Bacillus subtilis Bacteria Generate an Internal Mechanical Force within a Biofilm

(2015) Carine Douarche et al.   BIOPHYSICAL JOURNAL

The Mechanical World of Bacteria

(2015) Alexandre Persat et al.   CELL

Quantitative Imaging of Gut Microbiota Spatial Organization

(2015) Kristen A. Earle et al.   Cell Host & Microbe

The Surface Sensor NlpE of Enterohemorrhagic Escherichia coli Contributes to Regulation of the Type III Secretion System and Flagella by the Cpx Response to Adhesion

(2015) Takeshi Shimizu et al.   INFECTION AND IMMUNITY

Extracellular matrix structure governs invasion resistance in bacterial biofilms

(2015) Carey D Nadell et al.   ISME Journal

Live from under the lens: exploring microbial motility with dynamic imaging and microfluidics

(2015) Kwangmin Son et al.   NATURE REVIEWS MICROBIOLOGY

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Type IV pili mechanochemically regulate virulence factors inPseudomonas aeruginosa

(2015) Alexandre Persat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zinc-dependent mechanical properties ofStaphylococcus aureusbiofilm-forming surface protein SasG

(2015) Cécile Formosa-Dague et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host attachment and fluid shear are integrated into a mechanical signal regulating virulence inEscherichia coliO157:H7

(2015) Ghadah Alsharif et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Hierarchical Cascade of Second Messengers Regulates Pseudomonas aeruginosa Surface Behaviors

(2015) Yun Luo et al.   mBio

Micromanagement in the gut: microenvironmental factors govern colon mucosal biofilm structure and functionality

(2015) Rosemarie De Weirdt et al.   npj Biofilms and Microbiomes

Nanoscale Adhesion Forces of Pseudomonas aeruginosa Type IV Pili

(2014) Audrey Beaussart et al.   ACS Nano

Microfluidics Expanding the Frontiers of Microbial Ecology

(2014) Roberto Rusconi et al.   Annual Review of Biophysics

Cyclic Di-GMP-Mediated Repression of Swarming Motility by Pseudomonas aeruginosa PA14 Requires the MotAB Stator

(2014) S. L. Kuchma et al.   JOURNAL OF BACTERIOLOGY

The binding force of the staphylococcal adhesin SdrG is remarkably strong

(2014) Philippe Herman et al.   MOLECULAR MICROBIOLOGY

Surface attachment inducesPseudomonas aeruginosavirulence

(2014) Albert Siryaporn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Residence-time dependent cell wall deformation of different Staphylococcus aureus strains on gold measured using surface-enhanced-fluorescence

(2014) Jiuyi Li et al.   Soft Matter

Biofilms, flagella, and mechanosensing of surfaces by bacteria

(2014) Robert Belas   TRENDS IN MICROBIOLOGY

Dynamic Remodeling of Microbial Biofilms by Functionally Distinct Exopolysaccharides

(2014) S. C. Chew et al.   mBio

The curved shape of Caulobacter crescentus enhances surface colonization in flow

(2014) Alexandre Persat et al.   Nature Communications

Requirements for Pseudomonas aeruginosa Acute Burn and Chronic Surgical Wound Infection

(2014) Keith H. Turner et al.   PLoS Genetics

Single-Cell and Single-Molecule Analysis Deciphers the Localization, Adhesion, and Mechanics of the Biofilm Adhesin LapA

(2013) Sofiane El-Kirat-Chatel et al.   ACS Chemical Biology

Adhesion and Nanomechanics of Pili from the Probiotic Lactobacillus rhamnosus GG

(2013) Prachi Tripathi et al.   ACS Nano

Archaeal Biofilms: The Great Unexplored

(2013) Alvaro Orell et al.   Annual Review of Microbiology

Dynamic structural changes in microbial membranes in response to high hydrostatic pressure analyzed using time-resolved fluorescence anisotropy measurement

(2013) Fumiyoshi Abe   BIOPHYSICAL CHEMISTRY

Forces in Tissue Morphogenesis and Patterning

(2013) Carl-Philipp Heisenberg et al.   CELL

Solutions to the Public Goods Dilemma in Bacterial Biofilms

(2013) Knut Drescher et al.   CURRENT BIOLOGY

Hydrogel scaffolds to study cell biology in four dimensions

(2013) Katherine J.R. Lewis et al.   MRS BULLETIN

Dynamics of mechanosensing in the bacterial flagellar motor

(2013) P. P. Lele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrodynamics of soft active matter

(2013) M. C. Marchetti et al.   REVIEWS OF MODERN PHYSICS

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

The in vivo biofilm

(2013) Thomas Bjarnsholt et al.   TRENDS IN MICROBIOLOGY

Load-Dependent Assembly of the Bacterial Flagellar Motor

(2013) M. J. Tipping et al.   mBio

Pseudomonas aeruginosaTwitching Motility: Type IV Pili in Action

(2012) Lori L. Burrows   Annual Review of Microbiology

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

Stretching single polysaccharides and proteins using atomic force microscopy

(2012) Piotr E. Marszalek et al.   CHEMICAL SOCIETY REVIEWS

Mucin Biopolymers Prevent Bacterial Aggregation by Retaining Cells in the Free-Swimming State

(2012) Marina Caldara et al.   CURRENT BIOLOGY

Coordinated Cyclic-Di-GMP Repression of Salmonella Motility through YcgR and Cellulose

(2012) V. Zorraquino et al.   JOURNAL OF BACTERIOLOGY

Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

(2012) Brendon M. Baker et al.   JOURNAL OF CELL SCIENCE

Glitter-Like Iridescence within the Bacteroidetes Especially Cellulophaga spp.: Optical Properties and Correlation with Gliding Motility

(2012) Betty Kientz et al.   PLoS One

Osmotic spreading of Bacillus subtilis biofilms driven by an extracellular matrix

(2012) A. Seminara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-produced exopolysaccharide is a signal that stimulates biofilm formation in Pseudomonas aeruginosa

(2012) Y. Irie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Marine Microbes See a Sea of Gradients

(2012) R. Stocker   SCIENCE

Bacterial Cell Surface Deformation under External Loading

(2012) Y. Chen et al.   mBio

Surface contact stimulates the just-in-time deployment of bacterial adhesins

(2011) Guanglai Li et al.   MOLECULAR MICROBIOLOGY

Physicochemical regulation of biofilm formation

(2011) Lars D. Renner et al.   MRS BULLETIN

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Direct Measurement of Cell Wall Stress Stiffening and Turgor Pressure in Live Bacterial Cells

(2011) Yi Deng et al.   PHYSICAL REVIEW LETTERS

Mechanosensitive Channels: What Can They Do and How Do They Do It?

(2011) Elizabeth S. Haswell et al.   STRUCTURE

Structural Basis for Mechanical Force Regulation of the Adhesin FimH via Finger Trap-like β Sheet Twisting

(2010) Isolde Le Trong et al.   CELL

Isopeptide Bonds Block the Mechanical Extension of Pili in PathogenicStreptococcus pyogenes

(2010) Jorge Alegre-Cebollada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

The biofilm matrix

(2010) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

Force-induced formation and propagation of adhesion nanodomains in living fungal cells

(2010) D. Alsteens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Force-dependent polymorphism in type IV pili reveals hidden epitopes

(2010) N. Biais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid fibers provide structural integrity to Bacillus subtilis biofilms

(2010) D. Romero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Nonlinear viscoelastic biomaterials: meaningful characterization and engineering inspiration

(2009) R. H. Ewoldt et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Genetic Analysis of the Regulation of Type IV Pilus Function by the Chp Chemosensory System of Pseudomonas aeruginosa

(2009) J. J. Bertrand et al.   JOURNAL OF BACTERIOLOGY

Coupled Growth and Division of Model Protocell Membranes

(2009) Ting F. Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Force probing surfaces of living cells to molecular resolution

(2009) Daniel J Müller et al.   Nature Chemical Biology

Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein

(2009) M. Kankainen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The hydrodynamics of swimming microorganisms

(2009) Eric Lauga et al.   REPORTS ON PROGRESS IN PHYSICS

Recent Advances in Optical Tweezers

(2008) Jeffrey R. Moffitt et al.   Annual Review of Biochemistry

Catch Bonds in Adhesion

(2008) Wendy Thomas   Annual Review of Biomedical Engineering

Biophysics of Catch Bonds

(2008) Wendy E. Thomas et al.   Annual Review of Biophysics

The Deep-Sea Bacterium Photobacterium profundum SS9 Utilizes Separate Flagellar Systems for Swimming and Swarming under High-Pressure Conditions

(2008) E. A. Eloe et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

FimH Forms Catch Bonds That Are Enhanced by Mechanical Force Due to Allosteric Regulation

(2008) Olga Yakovenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

(2008) Keir C Neuman et al.   NATURE METHODS

Physiological heterogeneity in biofilms

(2008) Philip S. Stewart et al.   NATURE REVIEWS MICROBIOLOGY

Environmental Adaptation: Genomic Analysis of the Piezotolerant and Psychrotolerant Deep-Sea Iron Reducing Bacterium Shewanella piezotolerans WP3

(2008) Fengping Wang et al.   PLoS One

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pili in Gram-positive bacteria: assembly, involvement in colonization and biofilm development

(2008) Anjali Mandlik et al.   TRENDS IN MICROBIOLOGY

Molecular Basis for Staphylococcus aureus –Mediated Platelet Aggregate Formation Under Arterial Shear In Vitro

(2007) Steven W. Kerrigan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY