Anti-Inflammation Associated Protective Mechanism of Berberine and its Derivatives on Attenuating Pentylenetetrazole-Induced Seizures in Zebrafish

Synthesis and biological evaluation of new berberine derivatives as cancer immunotherapy agents through targeting IDO1

(2018) Yan–Xiang Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats

(2018) Ying Liu et al.   Journal of Neuroinflammation

Taurine Protects from Pentylenetetrazole-Induced Behavioral and Neurochemical Changes in Zebrafish

(2018) Barbara D. Fontana et al.   MOLECULAR NEUROBIOLOGY

Gastrodin Suppresses Pentylenetetrazole-Induced Seizures Progression by Modulating Oxidative Stress in Zebrafish

(2018) Meng Jin et al.   NEUROCHEMICAL RESEARCH

Berberine: Pathways to protect neurons

(2018) Xiaorui Lin et al.   PHYTOTHERAPY RESEARCH

Differential effects of TNF-α and IL-1β on the control of metal metabolism and cadmium-induced cell death in chronic inflammation

(2018) Paola Bonaventura et al.   PLoS One

Orthosiphon stamineus Leaf Extract Affects TNF-α and Seizures in a Zebrafish Model

(2018) Brandon Kar Meng Choo et al.   Frontiers in Pharmacology

Epilepsy

(2018) Orrin Devinsky et al.   Nature Reviews Disease Primers

Rifampicin ameliorates lithium-pilocarpine-induced seizures, consequent hippocampal damage and memory deficit in rats: Impact on oxidative, inflammatory and apoptotic machineries

(2018) Alaa E. Ali et al.   BIOCHEMICAL PHARMACOLOGY

Activation of BDNF-TrkB signaling pathway-regulated brain inflammation in pentylenetetrazole-induced seizures in zebrafish

(2018) Meng Jin et al.   FISH & SHELLFISH IMMUNOLOGY

Ghrelin improves pilocarpine‑induced cerebral cortex inflammation in epileptic rats by inhibiting NF‑κB and TNF‑α

(2018) Kun Han et al.   Molecular Medicine Reports

Modulation of P2X Purinoceptor 3 (P2X3) in Pentylenetetrazole-Induced Kindling Epilepsy in Rats

(2018) Jie Xia et al.   MEDICAL SCIENCE MONITOR

Cyclooxygenase-2 inhibitors differentially attenuate pentylenetetrazol-induced seizures and increase of pro- and anti-inflammatory cytokine levels in the cerebral cortex and hippocampus of mice

(2017) Fernanda Rossatto Temp et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency

(2017) Izabella A. Pena et al.   GENETICS

Sensitive analysis and pharmacokinetic study of epalrestat in C57BL/6J mice

(2017) Jingqiu Huang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Neuroprotective and Neuro-restorative Effects of Minocycline and Rasagiline in a Zebrafish 6-Hydroxydopamine Model of Parkinson’s Disease

(2017) Aileen Cronin et al.   NEUROSCIENCE

Cellular responses to recurrent pentylenetetrazole-induced seizures in the adult zebrafish brain

(2017) Phan Q. Duy et al.   NEUROSCIENCE

Anticonvulsant effect of sodium cyclamate and propylparaben on pentylenetetrazol-induced seizures in zebrafish

(2017) Antonella Pisera-Fuster et al.   SYNAPSE

Berberine attenuated pro-inflammatory factors and protect against neuronal damage via triggering oligodendrocyte autophagy in spinal cord injury

(2017) Hongyu Wang et al.   Oncotarget

Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency

(2017) Izabella A. Pena et al.   GENETICS

Zebrafish as a Model for Epilepsy-Induced Cognitive Dysfunction: A Pharmacological, Biochemical and Behavioral Approach

(2017) Uday P. Kundap et al.   Frontiers in Pharmacology

Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 pathways

(2017) Chao Zhang et al.   Redox Biology

Zebrafish as an animal model in epilepsy studies with multichannel EEG recordings

(2017) Sung-Joon Cho et al.   Scientific Reports

Indomethacin treatment prior to pentylenetetrazole-induced seizures downregulates the expression of il1b and cox2 and decreases seizure-like behavior in zebrafish larvae

(2016) Patrícia Gonçalves Barbalho et al.   BMC NEUROSCIENCE

Ceramide and Sphingosine-1-Phosphate in Cell Death Pathways : Relevance to the Pathogenesis of Alzheimer';s Disease

(2016) Sankha Shubhra Chakrabarti et al.   Current Alzheimer Research

Electrical Stimulation for Seizure Induction and Functional Mapping in Stereoelectroencephalography

(2016) Agnès Trébuchon et al.   JOURNAL OF CLINICAL NEUROPHYSIOLOGY

Brain inflammation is accompanied by peripheral inflammation in Cstb −/− mice, a model for progressive myoclonus epilepsy

(2016) Olesya Okuneva et al.   Journal of Neuroinflammation

Methamphetamine-induced neuronal necrosis: the role of electrographic seizure discharges

(2016) Denson G. Fujikawa et al.   NEUROTOXICOLOGY

Resveratrol suppressed seizures by attenuating IL-1β, IL1-Ra, IL-6, and TNF-α in the hippocampus and cortex of kindled mice

(2016) Ubedul Hoda et al.   NUTRITIONAL NEUROSCIENCE

Challenges in the clinical development of new antiepileptic drugs

(2016) Valentina Franco et al.   PHARMACOLOGICAL RESEARCH

Berberis Vulgarisand Berberine: An Update Review

(2016) Mohsen Imenshahidi et al.   PHYTOTHERAPY RESEARCH

EEG Radiotelemetry in Small Laboratory Rodents: A Powerful State-of-the Art Approach in Neuropsychiatric, Neurodegenerative, and Epilepsy Research

(2016) Andreas Lundt et al.   NEURAL PLASTICITY

Infections, inflammation and epilepsy

(2015) Annamaria Vezzani et al.   ACTA NEUROPATHOLOGICA

Valerenic acid and Valeriana officinalis extracts delay onset of Pentylenetetrazole (PTZ)-Induced seizures in adult Danio rerio (Zebrafish)

(2015) Bianca A. Torres-Hernández et al.   BMC Complementary and Alternative Medicine

Neuromodulatory properties of inflammatory cytokines and their impact on neuronal excitability

(2015) Annamaria Vezzani et al.   NEUROPHARMACOLOGY

Rapamycin suppresses PTZ-induced seizures at different developmental stages of zebrafish

(2015) Anna Maria Siebel et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Blood–brain barrier dysfunction, seizures and epilepsy

(2015) E.A. van Vliet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Seizures and Epilepsy: An Overview for Neuroscientists

(2015) C. E. Stafstrom et al.   Cold Spring Harbor Perspectives in Medicine

Citrus aurantium increases seizure latency to PTZ induced seizures in zebrafish thru NMDA and mGluR's I and II

(2015) Coral Rosa-Falero et al.   Frontiers in Pharmacology

Indomethacin can downregulate the levels of inflammatory mediators in the hippocampus of rats submitted to pilocarpine-induced status epilepticus

(2014) MJ Vieira et al.   Clinics

Inflammation and Epilepsy in the Developing Brain: Clinical and Experimental Evidence

(2014) Nina Dupuis et al.   CNS Neuroscience & Therapeutics

Berberine Protects against Neuronal Damage via Suppression of Glia-Mediated Inflammation in Traumatic Brain Injury

(2014) Chien-Cheng Chen et al.   PLoS One

Zebrafish models of human motor neuron diseases: Advantages and limitations

(2014) Patrick J. Babin et al.   PROGRESS IN NEUROBIOLOGY

Zebrafish models for translational neuroscience research: from tank to bedside

(2014) Adam Michael Stewart et al.   TRENDS IN NEUROSCIENCES

Tanshinone IIA Exhibits Anticonvulsant Activity in Zebrafish and Mouse Seizure Models

(2013) Olivia Erin Buenafe et al.   ACS Chemical Neuroscience

Berberine protects 6-hydroxydopamine-induced human dopaminergic neuronal cell death through the induction of heme oxygenase-1

(2013) Jinbum Bae et al.   MOLECULES AND CELLS

Synthesis and anticancer activity of a novel series of 9-O-substituted berberine derivatives: A lipophilic substitute role

(2012) Chih-Yu Lo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures

(2012) S. Baxendale et al.   Disease Models & Mechanisms

Berberine analogue IMB-Y53 improves glucose-lowering efficacy by averting cellular efflux especially P-glycoprotein efflux

(2012) Yong-Qiang Shan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Molecular cascades that mediate the influence of inflammation on epilepsy

(2011) Alon Friedman et al.   EPILEPSIA

8,8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models

(2010) Zhe Cheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Zebrafish as a model for studying genetic aspects of epilepsy

(2010) G. A. Hortopan et al.   Disease Models & Mechanisms

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands

(2009) Yan Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A role for leukocyte-endothelial adhesion mechanisms in epilepsy

(2008) Paolo F Fabene et al.   NATURE MEDICINE

Microglial activation and TNF  production mediate altered CNS excitability following peripheral inflammation

(2008) K. Riazi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA