Natural Polyphenols Targeting Senescence: A Novel Prevention and Therapy Strategy for Cancer
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Natural Polyphenols Targeting Senescence: A Novel Prevention and Therapy Strategy for Cancer
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 2, Pages 684
Publisher
MDPI AG
Online
2020-01-21
DOI
10.3390/ijms21020684
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity
- (2020) Sara Verdura et al. Aging-US
- Exhausted and Senescent T Cells at the Maternal-Fetal Interface in Preterm and Term Labor
- (2019) Rebecca Slutsky et al. Journal of Immunology Research
- Loss of KMT2D induces prostate cancer ROS-mediated DNA damage by suppressing the enhancer activity and DNA binding of antioxidant transcription factor FOXO3
- (2019) Shidong Lv et al. Epigenetics
- Anti-tumor Activity and Epigenetic Impact of the Polyphenol Oleacein in Multiple Myeloma
- (2019) Giada Juli et al. Cancers
- Senescence‐associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15
- (2019) Yuna Guo et al. AGING CELL
- Combinatorial Epigenetics Impact of Polyphenols and Phytochemicals in Cancer Prevention and Therapy
- (2019) Arora et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017
- (2019) et al. JAMA Oncology
- Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
- (2019) LaTonya J. Hickson et al. EBioMedicine
- Anti-inflammatory effects of flavonoids
- (2019) Soheila J. Maleki et al. FOOD CHEMISTRY
- Annurca apple polyphenol extract selectively kills MDA-MB-231 cells through ROS generation, sustained JNK activation and cell growth and survival inhibition
- (2019) Elisa Martino et al. Scientific Reports
- Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype
- (2019) Manuel J. Del Rey et al. Immunity & Ageing
- Identification and functional characterization of the transcription factor NF-κB subunit p65 in common carp (Cyprinus carpio L.)
- (2019) Shijuan Shan et al. FISH & SHELLFISH IMMUNOLOGY
- Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway
- (2019) Ruijie Sun et al. Cancer Medicine
- Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy
- (2018) Jiwei Wang et al. Autophagy
- Punicalagin induces senescent growth arrest in human papillary thyroid carcinoma BCPAP cells via NF-κB signaling pathway
- (2018) Xian Cheng et al. BIOMEDICINE & PHARMACOTHERAPY
- Impact of natural dietary agents on multiple myeloma prevention and treatment: molecular insights and potential for clinical translation
- (2018) Lavinia Raimondi et al. CURRENT MEDICINAL CHEMISTRY
- Curcumin as an Adjunct Therapy and microRNA Modulator in Breast Cancer
- (2018) Saeed Norouzi et al. CURRENT PHARMACEUTICAL DESIGN
- TERT regulates telomere-related senescence and apoptosis through DNA damage response in male germ cells exposed to BPDE in vitro and to B[ a ]P in vivo
- (2018) Xi Ling et al. ENVIRONMENTAL POLLUTION
- Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells
- (2018) Shuhua Ji et al. EXPERIMENTAL CELL RESEARCH
- Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri
- (2018) Shan Liu et al. FISH & SHELLFISH IMMUNOLOGY
- Hallmarks of Cellular Senescence
- (2018) Alejandra Hernandez-Segura et al. TRENDS IN CELL BIOLOGY
- Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling
- (2018) Zhou Wang et al. Cell Death & Disease
- E2F1 inhibition mediates cell death of metastatic melanoma
- (2018) Florian Rouaud et al. Cell Death & Disease
- Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016
- (2018) et al. JAMA Oncology
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- The p38-activated ER stress-ATF6α axis mediates cellular senescence
- (2018) Hee Suk Kim et al. FASEB JOURNAL
- Chronic Resveratrol Treatment Reduces the Pro-angiogenic Effect of Human Fibroblast “Senescent-Associated Secretory Phenotype” on Endothelial Colony-Forming Cells: The Role of IL8
- (2018) Beatrice Menicacci et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis
- (2018) Paul A Reyfman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- The dynamic nature of senescence in cancer
- (2018) Soyoung Lee et al. NATURE CELL BIOLOGY
- Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer
- (2017) Jiahui Xu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells
- (2017) Beatrice Menicacci et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Diosmin-induced senescence, apoptosis and autophagy in breast cancer cells of different p53 status and ERK activity
- (2017) Anna Lewinska et al. TOXICOLOGY LETTERS
- P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment
- (2017) Rong-Jane Chen et al. Cell Death & Disease
- Identification of a DNA Damage–Induced Alternative Splicing Pathway That Regulates p53 and Cellular Senescence Markers
- (2017) Jing Chen et al. Cancer Discovery
- Synergistic Interplay between Curcumin and Polyphenol-Rich Foods in the Mediterranean Diet: Therapeutic Prospects for Neurofibromatosis 1 Patients
- (2017) Teresa Esposito et al. Nutrients
- Resveratrol inhibits age-dependent spontaneous tumorigenesis by SIRT1-mediated post-translational modulations in the annual fish Nothobranchius guentheri
- (2017) Tingting Liu et al. Oncotarget
- Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells
- (2017) Kevin M. Perrott et al. GeroScience
- Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells
- (2017) Boxuan Li et al. Scientific Reports
- Cristacarpin promotes ER stress-mediated ROS generation leading to premature senescence by activation of p21waf-1
- (2016) Souneek Chakraborty et al. AGE
- Use of Polyphenolic Compounds in Dermatologic Oncology
- (2016) Adilson Costa et al. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
- Oroxin A inhibits breast cancer cell growth by inducing robust endoplasmic reticulum stress and senescence
- (2016) Jun He et al. ANTI-CANCER DRUGS
- Polyphenol compounds and PKC signaling
- (2016) Joydip Das et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Pinus radiata bark extract induces caspase-independent apoptosis-like cell death in MCF-7 human breast cancer cells
- (2016) Thamizhiniyan Venkatesan et al. CELL BIOLOGY AND TOXICOLOGY
- Downregulation of B-myb promotes senescenceviathe ROS-mediated p53/p21 pathway, in vascular endothelial cells
- (2016) Zhihui Zhou et al. CELL PROLIFERATION
- A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM–p53 signaling
- (2016) Yifan Wang et al. GENES & DEVELOPMENT
- Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation
- (2016) Tri Vuong et al. Journal of Translational Medicine
- Recent advances in research on lignans and neolignans
- (2016) Rémy Bertrand Teponno et al. NATURAL PRODUCT REPORTS
- ATM/CHK/p53 Pathway Dependent Chemopreventive and Therapeutic Activity on Lung Cancer by Pterostilbene
- (2016) Hani Lee et al. PLoS One
- Identification of cellular senescence-specific genes by comparative transcriptomics
- (2016) Taiki Nagano et al. Scientific Reports
- Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts
- (2015) Hyun Lim et al. BIOCHEMICAL PHARMACOLOGY
- Representative literature on the phytonutrients category: Phenolic acids
- (2015) Andrea Roche et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- FoxO3a suppresses the senescence of cardiac microvascular endothelial cells by regulating the ROS-mediated cell cycle
- (2015) Xu-Feng Qi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Resveratrol Represses Pokemon Expression in Human Glioma Cells
- (2015) Yutao Yang et al. MOLECULAR NEUROBIOLOGY
- Quercetin promotes cell apoptosis and inhibits the expression of MMP-9 and fibronectin via the AKT and ERK signalling pathways in human glioma cells
- (2015) Hong-Chao Pan et al. NEUROCHEMISTRY INTERNATIONAL
- High Potency of a Novel Resveratrol Derivative, 3,3′,4,4′-Tetrahydroxy-trans-stilbene, against Ovarian Cancer Is Associated with an Oxidative Stress-Mediated Imbalance between DNA Damage Accumulation and Repair
- (2015) Justyna Mikuła-Pietrasik et al. Oxidative Medicine and Cellular Longevity
- Mitigation of Fumonisin Biomarkers by Green Tea Polyphenols in a High-Risk Population of Hepatocellular Carcinoma
- (2015) Kathy S. Xue et al. Scientific Reports
- Resveratrol overcomes gefitinib resistance by increasing the intracellular gefitinib concentration and triggering apoptosis, autophagy and senescence in PC9/G NSCLC cells
- (2015) Yinsong Zhu et al. Scientific Reports
- Oxidative stress triggered by naturally occurring flavone apigenin results in senescence and chemotherapeutic effect in human colorectal cancer cells
- (2015) Kacoli Banerjee et al. Redox Biology
- Cellular senescence and aging: the role of B-MYB
- (2014) Sophia N. Mowla et al. AGING CELL
- Involvement of autophagy induction in penta-1,2,3,4,6-O-galloyl-β-D-glucose-induced senescence-like growth arrest in human cancer cells
- (2014) Yinhui Dong et al. Autophagy
- Inhibition of HDAC increases the senescence induced by natural polyphenols in glioma cells
- (2014) José E. Vargas et al. Biochemistry and Cell Biology
- Epigenetic regulation by selected dietary phytochemicals in cancer chemoprevention
- (2014) Samriddhi Shukla et al. CANCER LETTERS
- Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate
- (2014) Sabita N. Saldanha et al. EXPERIMENTAL CELL RESEARCH
- Resveratrol abrogates the Temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the Temozolomide-induced senescence in glioma cells
- (2013) Eduardo C Filippi-Chiela et al. BMC CANCER
- Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling
- (2013) Chun Wang et al. CARCINOGENESIS
- Programmed Cell Senescence during Mammalian Embryonic Development
- (2013) Daniel Muñoz-Espín et al. CELL
- Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
- (2013) Mekayla Storer et al. CELL
- Antitumor effects of naturally occurring oligomeric resveratrol derivatives
- (2013) Haishi Qiao et al. FASEB JOURNAL
- Coumestrol induces senescence through protein kinase CKII inhibition-mediated reactive oxygen species production in human breast cancer and colon cancer cells
- (2013) Young-Hoon Lee et al. FOOD CHEMISTRY
- Differential effects of polyphenols-enriched extracts from hawthorn fruit peels and fleshes on cell cycle and apoptosis in human MCF-7 breast carcinoma cells
- (2013) Ting Li et al. FOOD CHEMISTRY
- Quercetin suppresses invasion and migration of H-Ras-transformed MCF10A human epithelial cells by inhibiting phosphatidylinositol 3-kinase
- (2013) Nu Ry Song et al. FOOD CHEMISTRY
- Low concentration of metformin induces a p53-dependent senescence in hepatoma cells via activation of the AMPK pathway
- (2013) GAO YI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Resveratrol enhances ionizing radiation-induced premature senescence in lung cancer cells
- (2013) HONGMEI LUO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Isradipine prevents rotenone-induced intracellular calcium rise that accelerates senescence in human neuroblastoma SH-SY5Y cells
- (2013) X. Yu et al. NEUROSCIENCE
- Resveratrol Induces Premature Senescence in Lung Cancer Cells via ROS-Mediated DNA Damage
- (2013) Hongmei Luo et al. PLoS One
- Resveratrol Inhibits the Growth of Gastric Cancer by Inducing G1 Phase Arrest and Senescence in a Sirt1-Dependent Manner
- (2013) Qing Yang et al. PLoS One
- Resveratrol-Mediated Downregulation of Rictor Attenuates Autophagic Process and Suppresses UV-Induced Skin Carcinogenesis†
- (2012) Jung H. Back et al. PHOTOCHEMISTRY AND PHOTOBIOLOGY
- Resveratrol induces cellular senescence with attenuated mono-ubiquitination of histone H2B in glioma cells
- (2011) Zhen Gao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- IGFBP7 reduces breast tumor growth by induction of senescence and apoptosis pathways
- (2011) Tania Benatar et al. BREAST CANCER RESEARCH AND TREATMENT
- A Novel Prodrug of Epigallocatechin-3-gallate: Differential Epigenetic hTERT Repression in Human Breast Cancer Cells
- (2011) S. M. Meeran et al. Cancer Prevention Research
- Phase I Randomized, Double-Blind Pilot Study of Micronized Resveratrol (SRT501) in Patients with Hepatic Metastases--Safety, Pharmacokinetics, and Pharmacodynamics
- (2011) L. M. Howells et al. Cancer Prevention Research
- miR-22 represses cancer progression by inducing cellular senescence
- (2011) Dan Xu et al. JOURNAL OF CELL BIOLOGY
- Red wine polyphenols cause growth inhibition and apoptosis in acute lymphoblastic leukaemia cells by inducing a redox-sensitive up-regulation of p73 and down-regulation of UHRF1
- (2010) Tanveer Sharif et al. EUROPEAN JOURNAL OF CANCER
- The essence of senescence
- (2010) T. Kuilman et al. GENES & DEVELOPMENT
- Resveratrol and quercetin cooperate to induce senescence-like growth arrest in C6 rat glioma cells
- (2009) Lauren L. Zamin et al. CANCER SCIENCE
- Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1
- (2009) Marek Rusin et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Increased cell senescence is associated with decreased cell proliferation in vivo in the degenerating human annulus
- (2008) Helen E. Gruber et al. Spine Journal
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started