Downregulation of B-myb promotes senescenceviathe ROS-mediated p53/p21 pathway, in vascular endothelial cells

Inhibition of senescence and promotion of the proliferation of chondrocytes from articular cartilage by CsA and FK506 involves inhibition of p38MAPK

(2016) Seok-Won Kang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: Implications for Age-related Macular Degeneration

(2016) Mariela C. Marazita et al.   Redox Biology

Phenyl 2-pyridyl ketoxime induces cellular senescence-like alterations via nitric oxide production in human diploid fibroblasts

(2015) Kyeong Eun Yang et al.   AGING CELL

Age-related change in γH2AX of Drosophila muscle: its significance as a marker for muscle damage and longevity

(2015) Ho-Jun Jeon et al.   BIOGERONTOLOGY

Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses

(2015) Le Jiang et al.   CELL CYCLE

Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response

(2015) Shashi Kiran et al.   EXPERIMENTAL CELL RESEARCH

CUL4B impedes stress-induced cellular senescence by dampening a p53-reactive oxygen species positive feedback loop

(2015) Zhao Wei et al.   FREE RADICAL BIOLOGY AND MEDICINE

Early Evolution of Vertebrate Mybs: An Integrative Perspective Combining Synteny, Phylogenetic, and Gene Expression Analyses

(2015) Emeline B. Campanini et al.   Genome Biology and Evolution

The proliferation of amplifying neural progenitor cells is impaired in the aging brain and restored by the mTOR pathway activation

(2015) Jennifer Romine et al.   NEUROBIOLOGY OF AGING

Aging-associated changes in oxidative stress, cell proliferation, and apoptosis are prevented in the prostate of transgenic rats overexpressing regucalcin

(2015) Cátia V. Vaz et al.   Translational Research

Reactive oxygen species and p21Waf1/Cip1 are both essential for p53-mediated senescence of head and neck cancer cells

(2015) A L Fitzgerald et al.   Cell Death & Disease

Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

(2015) Ditte Kjærsgaard Klein et al.   Nature Communications

DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function

(2015) Qiujing Yu et al.   Cell Reports

Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway

(2015) Bahityar Rahmutulla et al.   Oncotarget

Cellular senescence and aging: the role of B-MYB

(2014) Sophia N. Mowla et al.   AGING CELL

Cellular senescence and its effector programs

(2014) R. Salama et al.   GENES & DEVELOPMENT

The Involvement of NADPH Oxidase-Mediated ROS in Cytokine Secretion from Macrophages Induced by Mycobacterium tuberculosis ESAT-6

(2014) Weiwei Liu et al.   INFLAMMATION

Oxidative Stress-induced Inhibition of Sirt1 by Caveolin-1 Promotes p53-dependent Premature Senescence and Stimulates the Secretion of Interleukin 6 (IL-6)

(2014) Daniela Volonte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species

(2014) S.-H. Ro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein kinase D1 is essential for Ras-induced senescence and tumor suppression by regulating senescence-associated inflammation

(2014) P. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development

(2014) S. J. Baker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial NADPH oxidases: which NOX to target in vascular disease?

(2014) Grant R. Drummond et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: Implications for vascular aging

(2013) María José Zarzuelo et al.   BIOCHEMICAL PHARMACOLOGY

Programmed Cell Senescence during Mammalian Embryonic Development

(2013) Daniel Muñoz-Espín et al.   CELL

Reactive oxygen species generated in different compartments induce cell death, survival, or senescence

(2013) Emiliano Panieri et al.   FREE RADICAL BIOLOGY AND MEDICINE

γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies

(2013) Vanessa Valdiglesias et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

A senescent cell bystander effect: senescence-induced senescence

(2012) Glyn Nelson et al.   AGING CELL

Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer

(2012) Ludmila Szabova et al.   CANCER RESEARCH

B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1)

(2012) Eugen Werwein et al.   CELL CYCLE

Cyclin-Dependent Kinase 5–Mediated Hyperphosphorylation of Sirtuin-1 Contributes to the Development of Endothelial Senescence and Atherosclerosis

(2012) Bo Bai et al.   CIRCULATION

Reactive Oxygen Species and Mitochondrial Sensitivity to Oxidative Stress Determine Induction of Cancer Cell Death by p21

(2012) Ionica Masgras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genistein accelerates refractory wound healing by suppressing superoxide and FoxO1/iNOS pathway in type 1 diabetes

(2012) Lu Tie et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The B-MYB Transcriptional Network Guides Cell Cycle Progression and Fate Decisions to Sustain Self-Renewal and the Identity of Pluripotent Stem Cells

(2012) Ming Zhan et al.   PLoS One

B-Myb, Cancer, Senescence, and MicroRNAs

(2011) I. Martinez et al.   CANCER RESEARCH

Imaging DNA Damage In Vivo Using  H2AX-Targeted Immunoconjugates

(2011) B. Cornelissen et al.   CANCER RESEARCH

Age-related changes in renal expression of oxidant and antioxidant enzymes and oxidative stress markers in male SHR and WKY rats

(2011) Sónia Simão et al.   EXPERIMENTAL GERONTOLOGY

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

(2011) Grant R. Drummond et al.   NATURE REVIEWS DRUG DISCOVERY

Loss of LIN9, a member of the DREAM complex, cooperates with SV40 large T antigen to induce genomic instability and anchorage-independent growth

(2011) S Hauser et al.   ONCOGENE

Two-fold elevation of expression of FoxM1 transcription factor in mouse embryonic fibroblasts enhances cell cycle checkpoint activity by stimulating p21 and Chk1 transcription

(2010) Y. Tan et al.   CELL PROLIFERATION

B-MYB delays cell aging by repressing p16 INK4α transcription

(2010) Yu Huang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

ARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf

(2010) J Song et al.   ONCOGENE

B-Myb is Critical for Proper DNA Duplication During an Unperturbed S Phase in Mouse Embryonic Stem Cells

(2010) Maëlle Lorvellec et al.   STEM CELLS

Endothelial dysfunction and aging: An update

(2009) María Dolores Herrera et al.   AGEING RESEARCH REVIEWS

B-MYB Is Required for Recovery from the DNA Damage-Induced G2 Checkpoint in p53 Mutant Cells

(2009) M. Mannefeld et al.   CANCER RESEARCH

H2AX phosphorylation as a genotoxicity endpoint

(2009) Gary Peter Watters et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Selective targeting of NADPH oxidase for cardiovascular protection

(2008) Alison Cave   CURRENT OPINION IN PHARMACOLOGY

Loss of Androgen Receptor in Aging and Oxidative Stress through Myb Protooncoprotein-regulated Reciprocal Chromatin Dynamics of p53 and Poly(ADP-ribose) Polymerase PARP-1

(2008) Liheng Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY