The Role of MicroRNAs in Mammalian Fertility: From Gametogenesis to Embryo Implantation

MicroRNA-30d deficiency during preconception affects endometrial receptivity by decreasing implantation rates and impairing fetal growth

(2019) Nuria Balaguer et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Extracellular vesicles of follicular fluid from heat-stressed cows modify the gene expression of in vitro-matured oocytes

(2019) Felipe Morales Dalanezi et al.   ANIMAL REPRODUCTION SCIENCE

Characterization of mRNA profiles of the exosome-like vesicles in porcine follicular fluid

(2019) Yuta Matsuno et al.   PLoS One

The biology of extracellular vesicles: The known unknowns

(2019) Leonid Margolis et al.   PLOS BIOLOGY

Differential microRNA Expression in Porcine Endometrium Involved in Remodeling and Angiogenesis That Contributes to Embryonic Implantation

(2019) Linjun Hong et al.   Frontiers in Genetics

Identification of Novel MicroRNAs and Characterization of MicroRNA Expression Profiles in Zebrafish Ovarian Follicular Cells

(2019) Yara Zayed et al.   Frontiers in Endocrinology

miR-21-3p inhibits autophagy of bovine granulosa cells by targeting VEGFA via PI3K/AKT signaling

(2019) Lizhu Ma et al.   REPRODUCTION

Overexpression of MicroRNA-10a in Germ Cells Causes Male Infertility by Targeting Rad51 in Mouse and Human

(2019) Huihui Gao et al.   Frontiers in Physiology

Sperm miR‐15a and miR‐29b are associated with bull fertility

(2019) Erika S. B. Menezes et al.   ANDROLOGIA

MicroRNA-375 regulates oocyte in vitro maturation by targeting ADAMTS1 and PGR in bovine cumulus cells

(2019) Jianrui Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Extracellular vesicle-coupled miRNA profiles in follicular fluid of cows with divergent post-calving metabolic status

(2019) Tsige Hailay et al.   Scientific Reports

MicroRNA-574 suppresses oocyte maturation via targeting hyaluronan synthase 2 in porcine cumulus cells

(2018) Bo Pan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

miR-1275 controls granulosa cell apoptosis and estradiol synthesis by impairing LRH-1/CYP19A1 axis

(2018) Jiying Liu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Testosterone-Dependent miR-26a-5p and let-7g-5p Act as Signaling Mediators to Regulate Sperm Apoptosis via Targeting PTEN and PMAIP1

(2018) Jideng Ma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Overexpression of MicroRNA-29b Decreases Expression of DNA Methyltransferases and Improves Quality of the Blastocysts Derived from Somatic Cell Nuclear Transfer in Cattle

(2018) Shuang Liang et al.   MICROSCOPY AND MICROANALYSIS

Oviductal extracellular vesicles (oviductosomes, OVS) are conserved in humans: murine OVS play a pivotal role in sperm capacitation and fertility

(2018) Pradeepthi Bathala et al.   MOLECULAR HUMAN REPRODUCTION

MicroRNA expression in bovine preimplantation embryos

(2018) Debra K. Berg et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Extracellular vesicles and their immunomodulatory functions in pregnancy

(2018) Soumyalekshmi Nair et al.   Seminars in Immunopathology

MicroRNA-424/503 cluster members regulate bovine granulosa cell proliferation and cell cycle progression by targeting SMAD7 gene through activin signalling pathway

(2018) Hari Om Pande et al.   Journal of Ovarian Research

Deciphering the oviductal extracellular vesicles content across the estrous cycle: implications for the gametes-oviduct interactions and the environment of the potential embryo

(2018) C. Almiñana et al.   BMC GENOMICS

Molecular regulation of miR-378 on the development of mouse follicle and the maturation of oocyte in vivo

(2018) Xiao-Feng Sun et al.   CELL CYCLE

microRNA-125b Regulates Apoptosis by Targeting Bone Morphogenetic Protein Receptor 1B in Yak Granulosa Cells

(2018) Yilong Yao et al.   DNA AND CELL BIOLOGY

miRNA-335-5p negatively regulates granulosa cell proliferation via SGK3 in PCOS

(2018) Lihua Yao et al.   REPRODUCTION

MiR-31 and miR-143 affect steroid hormone synthesis and inhibit cell apoptosis in bovine granulosa cells through FSHR

(2018) Zhe Zhang et al.   THERIOGENOLOGY

MiR-202 controls female fecundity by regulating medaka oogenesis

(2018) Stéphanie Gay et al.   PLoS Genetics

The microRNAs let-7 and miR-278 regulate insect metamorphosis and oogenesis by targeting the juvenile hormone early-response gene Krüppel-homolog 1

(2018) Jiasheng Song et al.   DEVELOPMENT

MiR-126-3p promotes the cell proliferation and inhibits the cell apoptosis by targeting TSC1 in the porcine granulosa cells

(2018) Xiaolong Yuan et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Extracellular vesicle mediated embryo-endometrial cross talk during implantation and in pregnancy

(2018) Noble K. Kurian et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

MiRNA-99a can regulate proliferation and apoptosis of human granulosa cells via targeting IGF-1R in polycystic ovary syndrome

(2018) Yudi Geng et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Extracellular microRNAs profile in human follicular fluid and IVF outcomes

(2018) Rosie M. Martinez et al.   Scientific Reports

The Role of Extracellular Vesicles and PIBF in Embryo-Maternal Immune-Interactions

(2018) Julia Szekeres-Bartho et al.   Frontiers in Immunology

The Adequate Corpus Luteum: miR-96 Promotes Luteal Cell Survival and Progesterone Production

(2017) Bushra T. Mohammed et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

MiRNA-143 mediates the proliferative signaling pathway of FSH and regulates estradiol production

(2017) Li Zhang et al.   JOURNAL OF ENDOCRINOLOGY

MicroRNA-224 delays oocyte maturation through targeting Ptx3 in cumulus cells

(2017) Xiufang Li et al.   MECHANISMS OF DEVELOPMENT

MicroRNA-27a-3p affects estradiol and androgen imbalance by targeting Creb1 in the granulosa cells in mouse polycytic ovary syndrome model

(2017) Mingming Wang et al.   Reproductive Biology

miR-181a increases FoxO1 acetylation and promotes granulosa cell apoptosis via SIRT1 downregulation

(2017) Mei Zhang et al.   Cell Death & Disease

MicroRNA-130b is involved in bovine granulosa and cumulus cells function, oocyte maturation and blastocyst formation

(2017) Pritam Bala Sinha et al.   Journal of Ovarian Research

Regulation of GVBD in mouse oocytes by miR-125a-3p and Fyn kinase through modulation of actin filaments

(2017) Hadas Grossman et al.   Scientific Reports

PPARγ is regulated by miR-27b-3p negatively and plays an important role in porcine oocyte maturation

(2016) Chunlei Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-183-96-182 Cluster Regulates Bovine Granulosa Cell Proliferation and Cell Cycle Transition by Coordinately Targeting FOXO11

(2016) Samuel Gebremedhn et al.   BIOLOGY OF REPRODUCTION

MicroRNA 17–92 cluster regulates proliferation and differentiation of bovine granulosa cells by targeting PTEN and BMPR2 genes

(2016) Eryk Andreas et al.   CELL AND TISSUE RESEARCH

miR-520 promotes DNA-damage-induced trophoblast cell apoptosis by targeting PARP1 in recurrent spontaneous abortion (RSA)

(2016) Xiujuan Dong et al.   GYNECOLOGICAL ENDOCRINOLOGY

Extracellular Vesicles from BOEC in In Vitro Embryo Development and Quality

(2016) Ricaurte Lopera-Vásquez et al.   PLoS One

Identification of candidate miRNAs and expression profile of yak oocytes before and after in vitro maturation by high-throughput sequencing

(2016) XR Xiong et al.   REPRODUCTION IN DOMESTIC ANIMALS

Characterization and Small RNA Content of Extracellular Vesicles in Follicular Fluid of Developing Bovine Antral Follicles

(2016) Raphatphorn Navakanitworakul et al.   Scientific Reports

MicroRNA in sperm from Duroc, Landrace and Yorkshire boars

(2016) Vanmathy Kasimanickam et al.   Scientific Reports

miR-762 promotes porcine immature Sertoli cell growth via the ring finger protein 4 (RNF4) gene

(2016) Changping Ma et al.   Scientific Reports

MicroRNA-378 regulates oocyte maturation via the suppression of aromatase in porcine cumulus cells

(2015) Bo Pan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MiR-143 and rat embryo implantation

(2015) Shi Tian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inhibition of Endometrial Tiam1/Rac1 Signals Induced by miR-22 Up-Regulation Leads to the Failure of Embryo Implantation During the Implantation Window in Pregnant Mice1

(2015) Hai-Lan Ma et al.   BIOLOGY OF REPRODUCTION

miR-23a and miR-27a Promote Human Granulosa Cell Apoptosis by Targeting SMAD51

(2015) Mingyue Nie et al.   BIOLOGY OF REPRODUCTION

MicroRNA-34a inhibits human trophoblast cell invasion by targeting MYC

(2015) Manni Sun et al.   BMC CELL BIOLOGY

Hsa-miR-30d, secreted by the human endometrium, is taken up by the pre-implantation embryo and might modify its transcriptome

(2015) F. Vilella et al.   DEVELOPMENT

Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development

(2015) Shuiqiao Yuan et al.   DEVELOPMENT

MicroRNA-451 plays a role in murine embryo implantation through targeting Ankrd46, as implicated by a microarray-based analysis

(2015) Zhengyu Li et al.   FERTILITY AND STERILITY

Regulation of Pattern Formation and Gene Amplification During Drosophila Oogenesis by the miR-318 microRNA

(2015) W. Ge et al.   GENETICS

MicroRNA-429 functions as a regulator of epithelial–mesenchymal transition by targeting Pcdh8 during murine embryo implantation

(2015) Zhengyu Li et al.   HUMAN REPRODUCTION

Extracellular vesicles: roles in gamete maturation, fertilization and embryo implantation

(2015) Ronit Machtinger et al.   HUMAN REPRODUCTION UPDATE

MicroRNA-764-3p regulates 17β-estradiol synthesis of mouse ovarian granulosa cells by targeting steroidogenic factor-1

(2015) Lianlian Wang et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

miR-145 suppresses embryo-epithelial juxtacrine communication at implantation by modulating maternal IGF1R

(2015) Y.-J. Kang et al.   JOURNAL OF CELL SCIENCE

Characterization of microRNA in bovine in vitro culture media associated with embryo quality and development

(2015) Jenna Kropp et al.   JOURNAL OF DAIRY SCIENCE

MicroRNA Expression Profile in Bovine Granulosa Cells of Preovulatory Dominant and Subordinate Follicles during the Late Follicular Phase of the Estrous Cycle

(2015) Samuel Gebremedhn et al.   PLoS One

MicroRNA-132 promotes estradiol synthesis in ovarian granulosa cells via translational repression of Nurr1

(2015) Shaogen Wu et al.   Reproductive Biology and Endocrinology

Mmu-miR-126a-3p plays a role in murine embryo implantation by regulating Itga11

(2015) Zhengyu Li et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Differential expression of microRNAs in sexually immature and mature canine testes

(2015) Vanmathy R. Kasimanickam et al.   THERIOGENOLOGY

miRNA-181 regulates embryo implantation in mice through targeting leukemia inhibitory factor

(2015) Bo Chu et al.   Journal of Molecular Cell Biology

Dramatic Changes in 67 miRNAs During Initiation of First Wave of Spermatogenesis in Mus musculusTestis: Global Regulatory Insights Generated by miRNA-mRNA Network Analysis1

(2014) Sreesha Sree et al.   BIOLOGY OF REPRODUCTION

Differential Expression of miRNAs and Their Target mRNAs in Endometria Prior to Maternal Recognition of Pregnancy Associates with Endometrial Receptivity for In Vivo- and In Vitro-Produced Bovine Embryos1

(2014) Siriluck Ponsuksili et al.   BIOLOGY OF REPRODUCTION

MiR-92a inhibits porcine ovarian granulosa cell apoptosis by targetingSmad7gene

(2014) Jiying Liu et al.   FEBS LETTERS

Molecular characterization of exosomes and their microRNA cargo in human follicular fluid: bioinformatic analysis reveals that exosomal microRNAs control pathways involved in follicular maturation

(2014) Manuela Santonocito et al.   FERTILITY AND STERILITY

MicroRNAs and spermatogenesis

(2014) Noora Kotaja   FERTILITY AND STERILITY

MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos

(2014) A. W. Y. Cheong et al.   HUMAN REPRODUCTION

Drosha protein levels are translationally regulated during Xenopus oocyte maturation

(2014) Dominik Muggenhumer et al.   MOLECULAR BIOLOGY OF THE CELL

The Expression Pattern of microRNAs in Granulosa Cells of Subordinate and Dominant Follicles during the Early Luteal Phase of the Bovine Estrous Cycle

(2014) Dessie Salilew-Wondim et al.   PLoS One

Characterization of microRNAs differentially expressed during bovine follicle development

(2014) Sadanand D Sontakke et al.   REPRODUCTION

Regulation of ACVR1 and ID2 by cell-secreted exosomes during follicle maturation in the mare

(2014) Juliano C da Silveira et al.   Reproductive Biology and Endocrinology

MicroRNA-34 family expression in bovine gametes and preimplantation embryos

(2014) Allison Tscherner et al.   Reproductive Biology and Endocrinology

The Differential Expression of MicroRNAs Between Implantation Sites and Interimplantation Sites in Early Pregnancy in Mice and Their Potential Functions

(2014) Yanqing Geng et al.   Reproductive Sciences

SOX9 Regulates MicroRNA miR-202-5p/3p Expression During Mouse Testis Differentiation1

(2013) Elanor N. Wainwright et al.   BIOLOGY OF REPRODUCTION

Exosomes Secreted by Human Placenta Carry Functional Fas Ligand and TRAIL Molecules and Convey Apoptosis in Activated Immune Cells, Suggesting Exosome-Mediated Immune Privilege of the Fetus

(2013) A.-C. Stenqvist et al.   JOURNAL OF IMMUNOLOGY

Endometrial Exosomes/Microvesicles in the Uterine Microenvironment: A New Paradigm for Embryo-Endometrial Cross Talk at Implantation

(2013) York Hunt Ng et al.   PLoS One

Transcriptome Profiling of the Murine Testis during the First Wave of Spermatogenesis

(2013) Asta Laiho et al.   PLoS One

Possible Roles of mmu-miR-141 in the Endometrium of Mice in Early Pregnancy Following Embryo Implantation

(2013) Xueqing Liu et al.   PLoS One

Exosomal and Non-Exosomal Transport of Extra-Cellular microRNAs in Follicular Fluid: Implications for Bovine Oocyte Developmental Competence

(2013) Md. Mahmodul Hasan Sohel et al.   PLoS One

Expression and Secretion of Plasma Membrane Ca2+-ATPase 4a (PMCA4a) during Murine Estrus: Association with Oviductal Exosomes and Uptake in Sperm

(2013) Amal A. Al-Dossary et al.   PLoS One

Bidirectional communication between oocytes and ovarian follicular somatic cells is required for meiotic arrest of mammalian oocytes

(2013) K. Wigglesworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR199a is implicated in embryo implantation by regulating Grb10 in rat

(2013) Hong-Fei Xia et al.   REPRODUCTION

Mmu-miR-193 Is Involved in Embryo Implantation in Mouse Uterus by Regulating GRB7 Gene Expression

(2013) Rong Li et al.   Reproductive Sciences

Mmu-microRNA-200a Overexpression Leads to Implantation Defect by Targeting Phosphatase and Tensin Homolog in Mouse Uterus

(2013) Lian-Ju Shen et al.   Reproductive Sciences

Regulatory microRNA Network Identification in Bovine Blastocyst Development

(2013) Karen Goossens et al.   STEM CELLS AND DEVELOPMENT

Pregnancy recognition signaling mechanisms in ruminants and pigs

(2013) Fuller W Bazer   Journal of Animal Science and Biotechnology

Oviductal, endometrial and embryonic gene expression patterns as molecular clues for pregnancy establishment

(2012) Dessie Salilew-Wondim et al.   ANIMAL REPRODUCTION SCIENCE

Global gene expression of the inner cell mass and trophectoderm of the bovine blastocyst

(2012) Manabu Ozawa et al.   BMC DEVELOPMENTAL BIOLOGY

Solexa Sequencing of Novel and Differentially Expressed MicroRNAs in Testicular and Ovarian Tissues in Holstein Cattle

(2012) Jinming Huang et al.   International Journal of Biological Sciences

miR-122 regulates hepatic lipid metabolism and tumor suppression

(2012) Jessica Wen et al.   JOURNAL OF CLINICAL INVESTIGATION

Analysis of microRNAs and their precursors in bovine early embryonic development

(2012) E. Mondou et al.   MOLECULAR HUMAN REPRODUCTION

MicroRNA expression profiles of trophoblastic cells

(2012) D.M. Morales-Prieto et al.   PLACENTA

Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice

(2012) Wei-Min Liu et al.   PLoS One

Micro-RNA378 (miR-378) Regulates Ovarian Estradiol Production by Targeting Aromatase

(2011) Shengyu Xu et al.   ENDOCRINOLOGY

Genome-wide identification of micro-ribonucleic acids associated with human endometrial receptivity in natural and stimulated cycles by deep sequencing

(2011) Ai-Guo Sha et al.   FERTILITY AND STERILITY

MicroRNAs are associated with human embryo implantation defects

(2011) Ariel Revel et al.   HUMAN REPRODUCTION

Microarray analysis of differentially expressed microRNAs in non-regressed and regressed bovine corpus luteum tissue; microRNA-378 may suppress luteal cell apoptosis by targeting the interferon gamma receptor 1 gene

(2011) Tenghe Ma et al.   JOURNAL OF APPLIED GENETICS

Expression analysis of regulatory microRNAs in bovine cumulus oocyte complex and preimplantation embryos

(2011) W.S. Abd El Naby et al.   ZYGOTE

Cloning and analysis of fetal ovary microRNAs in cattle

(2010) Swamy K. Tripurani et al.   ANIMAL REPRODUCTION SCIENCE

An Early Developmental Role for miRNAs in the Maintenance of Extraembryonic Stem Cells in the Mouse Embryo

(2010) Thomas Spruce et al.   DEVELOPMENTAL CELL

Blastocyst gene expression correlates with implantation potential

(2010) Jason C. Parks et al.   FERTILITY AND STERILITY

The role of small non-coding RNAs in genome stability and chromatin organization

(2010) J. C. van Wolfswinkel et al.   JOURNAL OF CELL SCIENCE

Bovine pretransfer endometrium and embryo transcriptome fingerprints as predictors of pregnancy success after embryo transfer

(2010) Dessie Salilew-Wondim et al.   PHYSIOLOGICAL GENOMICS

Analysis of MicroRNA Expression in the Prepubertal Testis

(2010) Gregory M. Buchold et al.   PLoS One

Identification and characterization of miRNAs expressed in the bovine ovary

(2009) Md Hossain et al.   BMC GENOMICS

MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells

(2009) Na Xu et al.   CELL

Hsa-miR-222 Is Involved in Differentiation of Endometrial Stromal Cellsin Vitro

(2009) Kun Qian et al.   ENDOCRINOLOGY

The regulatory role of Dicer in folliculogenesis in mice

(2009) Lei Lei et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Novel pathways for implantation and establishment and maintenance of pregnancy in mammals

(2009) F. W. Bazer et al.   MOLECULAR HUMAN REPRODUCTION

Identification and expression profiling of microRNAs during bovine oocyte maturation using heterologous approach

(2009) Dawit Tesfaye et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

microRNA Expression during Trophectoderm Specification

(2009) Srinivas R. Viswanathan et al.   PLoS One

Essential role for Argonaute2 protein in mouse oogenesis

(2009) Masahiro Kaneda et al.   Epigenetics & Chromatin

miR-17 family miRNAs are expressed during early mammalian development and regulate stem cell differentiation

(2008) Kara M. Foshay et al.   DEVELOPMENTAL BIOLOGY

MicroRNA Expression and Regulation in Mouse Uterus during Embryo Implantation

(2008) Shi-Jun Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms regulating bovine ovarian follicular selection

(2008) Zhilin Liu et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo

(2008) W. A. Kues et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preimplantation embryo programming: transcription, epigenetics, and culture environment

(2008) Veronique Duranthon et al.   REPRODUCTION