News about the Role of the Transcription Factor REST in Neurons: From Physiology to Pathology
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Title
News about the Role of the Transcription Factor REST in Neurons: From Physiology to Pathology
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 1, Pages 235
Publisher
MDPI AG
Online
2019-12-30
DOI
10.3390/ijms21010235
References
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Note: Only part of the references are listed.- Transcriptional repressor REST drives lineage stage–specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma
- (2019) Tara H. W. Dobson et al. Science Signaling
- REST/NRSF transcription factor is overexpressed in hippocampus of patients with drug-resistant mesial temporal lobe epilepsy
- (2019) Victor Navarrete-Modesto et al. EPILEPSY & BEHAVIOR
- REST: An epigenetic regulator of neuronal stress responses in the young and ageing brain
- (2019) Myrthe Mampay et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Loss of nuclear REST/NRSF in aged-dopaminergic neurons in Parkinson’s disease patients
- (2019) Miwako Kawamura et al. NEUROSCIENCE LETTERS
- The interaction between RE1-silencing transcription factor (REST) and heat shock protein 90 as new therapeutic target against Huntington’s disease
- (2019) Raúl Orozco-Díaz et al. PLoS One
- Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness
- (2018) Yoko Nakano et al. CELL
- REST, a master transcriptional regulator in neurodegenerative disease
- (2018) Jee-Yeon Hwang et al. CURRENT OPINION IN NEUROBIOLOGY
- MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts
- (2018) Seong Won Lee et al. DEVELOPMENTAL CELL
- Novel Rest functions revealed by conditional gene ablation
- (2018) Hitomi Aoki Medical Molecular Morphology
- REST, regulated by RA through miR-29a and the proteasome pathway, plays a crucial role in RPC proliferation and differentiation
- (2018) Yuyao Wang et al. Cell Death & Disease
- Prion protein is essential for the RE1 silencing transcription factor (REST)-dependent developmental switch in synaptic NMDA receptors
- (2018) Zhiqi Song et al. Cell Death & Disease
- NRSF/REST levels are decreased in cholangiocellular carcinoma but not hepatocellular carcinoma compared with normal liver tissues: A tissue microarray study
- (2018) Yanlan Yu et al. Oncology Letters
- Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration
- (2018) Keri Callegari et al. Cell Communication and Signaling
- PEI-Coated Fe3O4 Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells
- (2018) Rui Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Phosphatase activity of Small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST)
- (2018) Nathaniel Tate Burkholder et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sertraline, chlorprothixene, and chlorpromazine characteristically interact with the REST-binding site of the corepressor mSin3, showing medulloblastoma cell growth inhibitory activities
- (2018) Jun-ichi Kurita et al. Scientific Reports
- RE1-silencing transcription factor controls the acute-to-chronic neuropathic pain transition and Chrm2 receptor gene expression in primary sensory neurons
- (2018) Jixiang Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Knockdown of NRSF inhibits cell proliferation of ovarian cancer via activating Hippo pathway
- (2018) Pengfei Deng et al. LIFE SCIENCES
- Epigenetic regulator UHRF1 inactivates REST and growth suppressor gene expression via DNA methylation to promote axon regeneration
- (2018) Young Mi Oh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulation of nuclear REST by alternative splicing: a potential therapeutic target for Huntington's disease
- (2017) Guo-Lin Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Enduring Memory Impairments Provoked by Developmental Febrile Seizures Are Mediated by Functional and Structural Effects of Neuronal Restrictive Silencing Factor
- (2017) Katelin P. Patterson et al. JOURNAL OF NEUROSCIENCE
- Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation
- (2017) Tara H.W. Dobson et al. MOLECULAR CANCER RESEARCH
- Molecular mechanisms and potential prognostic effects of REST and REST4 in glioma
- (2017) Cuilin Li et al. Molecular Medicine Reports
- NRSF-dependent epigenetic mechanisms contribute to programming of stress-sensitive neurons by neonatal experience, promoting resilience
- (2017) A Singh-Taylor et al. MOLECULAR PSYCHIATRY
- Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
- (2017) Jing Shan Lim et al. NATURE
- The emerging field of epigenetics in neurodegeneration and neuroprotection
- (2017) Jee-Yeon Hwang et al. NATURE REVIEWS NEUROSCIENCE
- Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling
- (2017) Zhiqi Song et al. NEUROPHARMACOLOGY
- Demethylation of Repressor Element-1 Silencing Transcription (REST) Suppresses the Malignant Phenotype of Breast Cancer via MMP9
- (2017) Ying Liu et al. ONCOLOGY RESEARCH
- Stepwise assembly of functional C-terminal REST/NRSF transcriptional repressor complexes as a drug target
- (2017) Ken Inui et al. PROTEIN SCIENCE
- Plasma REST: a novel candidate biomarker of Alzheimer’s disease is modified by psychological intervention in an at-risk population
- (2017) N J Ashton et al. Translational Psychiatry
- REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer
- (2017) Yi-Ting Chang et al. Scientific Reports
- NRSF and BDNF polymorphisms as biomarkers of cognitive dysfunction in adults with newly diagnosed epilepsy
- (2016) Alix Warburton et al. EPILEPSY & BEHAVIOR
- RE1-silencing Transcription Factor (REST) Is Required for Nuclear Reprogramming by Inhibiting Transforming Growth Factor β Signaling Pathway
- (2016) Qing-Ran Kong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lithium-induced neuroprotection in stroke involves increased miR-124 expression, reduced RE1-silencing transcription factor abundance and decreased protein deubiquitination by GSK3β inhibition-independent pathways
- (2016) Thorsten R Doeppner et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Brain REST/NRSF Is Not Only a Silent Repressor but Also an Active Protector
- (2016) Yangang Zhao et al. MOLECULAR NEUROBIOLOGY
- REST regulation of gene networks in adult neural stem cells
- (2016) Shradha Mukherjee et al. Nature Communications
- Dual and Opposing Roles of MicroRNA-124 in Epilepsy Are Mediated through Inflammatory and NRSF-Dependent Gene Networks
- (2016) Gary P. Brennan et al. Cell Reports
- Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation
- (2016) Namgyu Lee et al. Scientific Reports
- TSPYL2 is an essential component of the REST/NRSF transcriptional complex for TGFβ signaling activation
- (2015) M T Epping et al. CELL DEATH AND DIFFERENTIATION
- REST represses a subset of the pancreatic endocrine differentiation program
- (2015) David Martin et al. DEVELOPMENTAL BIOLOGY
- REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II
- (2015) H. J. Kim et al. JOURNAL OF NEUROSCIENCE
- NRSF is an essential mediator for the neuroprotection of trichostatin A in the MPTP mouse model of Parkinson's disease
- (2015) Haiyun Suo et al. NEUROPHARMACOLOGY
- Schizophrenia: Evidence implicating hippocampal GluN2B protein and REST epigenetics in psychosis pathophysiology
- (2015) C.A. Tamminga et al. NEUROSCIENCE
- REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation
- (2015) Jose M. Garcia-Manteiga et al. Frontiers in Cellular Neuroscience
- NRSF: an Angel or a Devil in Neurogenesis and Neurological Diseases
- (2014) Zhiqi Song et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- REST and stress resistance in ageing and Alzheimer’s disease
- (2014) Tao Lu et al. NATURE
- PHF8 and REST/NRSF co-occupy gene promoters to regulate proximal gene expression
- (2014) Juan Wang et al. Scientific Reports
- The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes
- (2014) Shawn McClelland et al. eLife
- The promise and perils of HDAC inhibitors in neurodegeneration
- (2014) Alessandro Didonna et al. Annals of Clinical and Translational Neurology
- MicroRNAs: regulators of neuronal fate
- (2013) Alfred X Sun et al. CURRENT OPINION IN CELL BIOLOGY
- REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
- (2013) C. Svensson et al. NUCLEIC ACIDS RESEARCH
- High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes
- (2013) Jérémie Charbord et al. STEM CELLS
- A Genome-Wide Screen for Genetic Variants That Modify the Recruitment of REST to Its Target Genes
- (2012) Rory Johnson et al. PLoS Genetics
- The economic cost of brain disorders in Europe
- (2011) J. Olesen et al. EUROPEAN JOURNAL OF NEUROLOGY
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