High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes

Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells

(2012) Mahru C. An et al.   Cell Stem Cell

REST regulates the pool size of the different neural lineages by restricting the generation of neurons and oligodendrocytes from neural stem/progenitor cells

(2012) M. V. Covey et al.   DEVELOPMENT

In vivo delivery of DN:REST improves transcriptional changes of REST-regulated genes in HD mice

(2012) P Conforti et al.   GENE THERAPY

Early transcriptional changes linked to naturally occurring Huntington's disease mutations in neural derivatives of human embryonic stem cells

(2012) Maxime Feyeux et al.   HUMAN MOLECULAR GENETICS

A signaling loop of REST, TSC2 and  -catenin governs proliferation and function of PC12 neural cells

(2011) R. Tomasoni et al.   JOURNAL OF CELL SCIENCE

Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells

(2011) Zhi Huang et al.   NATURE CELL BIOLOGY

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

(2011) Alan H. Nagahara et al.   NATURE REVIEWS DRUG DISCOVERY

Repressor Element 1 Silencing Transcription Factor Couples Loss of Pluripotency with Neural Induction and Neural Differentiation

(2011) Chiara Soldati et al.   STEM CELLS

BMP-induced REST regulates the establishment and maintenance of astrocytic identity

(2010) Jun Kohyama et al.   JOURNAL OF CELL BIOLOGY

Transcriptional Activation of REST by Sp1 in Huntington's Disease Models

(2010) Myriam Ravache et al.   PLoS One

Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions

(2010) J. J. Abrajano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Turning REST/NRSF Dysfunction in Huntingtons Disease into a Pharmaceutical Target

(2009) Dorotea Rigamonti et al.   CURRENT PHARMACEUTICAL DESIGN

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Phosphodiesterase 10 inhibition reduces striatal excitotoxicity in the quinolinic acid model of Huntington's disease

(2009) Carmela Giampà et al.   NEUROBIOLOGY OF DISEASE

Differential Deployment of REST and CoREST Promotes Glial Subtype Specification and Oligodendrocyte Lineage Maturation

(2009) Joseph J. Abrajano et al.   PLoS One

REST and CoREST Modulate Neuronal Subtype Specification, Maturation and Maintenance

(2009) Joseph J. Abrajano et al.   PLoS One

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

BDNF and the diseased nervous system: a delicate balance between adaptive and pathological processes of gene regulation

(2008) Yinghui Hu et al.   JOURNAL OF NEUROCHEMISTRY

Enhanced Sensitivity of Striatal Neurons to Axonal Transport Defects Induced by Mutant Huntingtin

(2008) L.-S. Her et al.   JOURNAL OF NEUROSCIENCE

REST maintains self-renewal and pluripotency of embryonic stem cells

(2008) Sanjay K. Singh et al.   NATURE

SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation

(2008) Thomas F. Westbrook et al.   NATURE

Control of chromosome stability by the β-TrCP–REST–Mad2 axis

(2008) Daniele Guardavaccaro et al.   NATURE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

REST Regulates Distinct Transcriptional Networks in Embryonic and Neural Stem Cells

(2008) Rory Johnson et al.   PLOS BIOLOGY

A microRNA-based gene dysregulation pathway in Huntington's disease

(2007) Rory Johnson et al.   NEUROBIOLOGY OF DISEASE

Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions

(2007) Z. De March et al.   NEUROSCIENCE