Targeting Age-Dependent Functional and Metabolic Decline of Human Skeletal Muscle: The Geroprotective Role of Exercise, Myokine IL-6, and Vitamin D
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Title
Targeting Age-Dependent Functional and Metabolic Decline of Human Skeletal Muscle: The Geroprotective Role of Exercise, Myokine IL-6, and Vitamin D
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 3, Pages 1010
Publisher
MDPI AG
Online
2020-02-05
DOI
10.3390/ijms21031010
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Note: Only part of the references are listed.- Roles of myokines in exercise-induced improvement of neuropsychiatric function
- (2019) Sujin Kim et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Comparative study of testosterone and vitamin D analogue, elocalcitol, on insulin-controlled signal transduction pathway regulation in human skeletal muscle cells
- (2019) C. Antinozzi et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- Signals from the Niche: Insights into the Role of IGF-1 and IL-6 in Modulating Skeletal Muscle Fibrosis
- (2019) Laura Forcina et al. Cells
- Role of Myokines in Regulating Skeletal Muscle Mass and Function
- (2019) Jong Han Lee et al. Frontiers in Physiology
- Lifelong aerobic exercise protects against inflammaging and cancer
- (2019) Mats I. Nilsson et al. PLoS One
- Role of myokines in the development of skeletal muscle insulin resistance and related metabolic defects in type 2 diabetes
- (2019) L. Garneau et al. DIABETES & METABOLISM
- Vitamin K Status and Mobility Limitation and Disability in Older Adults: The Health, Aging, and Body Composition Study
- (2019) M Kyla Shea et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Myokines in metabolic homeostasis and diabetes
- (2019) Jürgen Eckel DIABETOLOGIA
- Geroprotectors: A role in the treatment of frailty
- (2019) A.U. Trendelenburg et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Inflammaging and Oxidative Stress in Human Diseases: From Molecular Mechanisms to Novel Treatments
- (2019) Zuo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Vitamin K as a Powerful Micronutrient in Aging and Age-Related Diseases: Pros and Cons from Clinical Studies
- (2019) Dina C. Simes et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- If my muscle could talk: Myokines as a biomarker of frailty
- (2019) Hélio J. Coelho-Junior et al. EXPERIMENTAL GERONTOLOGY
- Sarcopenia: An Overview on Current Definitions, Diagnosis and Treatment
- (2018) Francesco Landi et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Effects of Vitamin D on Skeletal Muscle and Athletic Performance
- (2018) Geoffrey D. Abrams et al. JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
- Effects of vitamin D on insulin resistance and myosteatosis in diet-induced obese mice
- (2018) Elisa Benetti et al. PLoS One
- Inhibition of interleukin-6 decreases atrogene expression and ameliorates tail suspension-induced skeletal muscle atrophy
- (2018) Mitsutaka Yakabe et al. PLoS One
- Debunking the Myth of Exercise-Induced Immune Suppression: Redefining the Impact of Exercise on Immunological Health Across the Lifespan
- (2018) John P. Campbell et al. Frontiers in Immunology
- Maintenance of Skeletal Muscle Mitochondria in Health, Exercise, and Aging
- (2018) David A. Hood et al. Annual Review of Physiology
- Age-related changes in skeletal muscle: changes to life-style as a therapy
- (2018) Rachel McCormick et al. BIOGERONTOLOGY
- Impaired proteostasis during skeletal muscle aging
- (2018) Raquel Fernando et al. FREE RADICAL BIOLOGY AND MEDICINE
- Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
- (2018) Luigi Ferrucci et al. Nature Reviews Cardiology
- Targeting mitochondrial quality control for treating sarcopenia: lessons from physical exercise
- (2018) Anna Picca et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- The controversial role of vitamin D as an antioxidant: results from randomised controlled trials
- (2018) Sara Tagliaferri et al. NUTRITION RESEARCH REVIEWS
- The compelling link between physical activity and the body's defense system
- (2018) David C. Nieman et al. Journal of Sport and Health Science
- Potential role for the VDR agonist elocalcitol in metabolic control: Evidences in human skeletal muscle cells
- (2017) Cristina Antinozzi et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Nonpharmacological interventions to treat physical frailty and sarcopenia in older patients: a systematic overview – the SENATOR Project ONTOP Series
- (2017) Isabel Lozano-Montoya et al. Clinical Interventions in Aging
- Role of muscle IL-6 in gender-specific metabolism in mice
- (2017) Amalia Molinero et al. PLoS One
- Exercise Promotes Healthy Aging of Skeletal Muscle
- (2016) Gregory D. Cartee et al. Cell Metabolism
- Associations of total amount and patterns of sedentary behaviour with type 2 diabetes and the metabolic syndrome: The Maastricht Study
- (2016) Julianne D. van der Berg et al. DIABETOLOGIA
- Insulin resistance and sarcopenia: mechanistic links between common co-morbidities
- (2016) Mark E Cleasby et al. JOURNAL OF ENDOCRINOLOGY
- Inflammaging and Skeletal Muscle: Can Protein Intake Make a Difference?
- (2016) Dimitrios Draganidis et al. JOURNAL OF NUTRITION
- Role of reactive oxygen species in age-related neuromuscular deficits
- (2016) Malcolm J. Jackson et al. JOURNAL OF PHYSIOLOGY-LONDON
- Do antioxidant supplements interfere with skeletal muscle adaptation to exercise training?
- (2016) Troy L. Merry et al. JOURNAL OF PHYSIOLOGY-LONDON
- Mechanisms for greater insulin-stimulated glucose uptake in normal and insulin-resistant skeletal muscle after acute exercise
- (2015) Gregory D. Cartee AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Inflammaging and Anti-Inflammaging: The Role of Cytokines in Extreme Longevity
- (2015) Paola Lucia Minciullo et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- 1α,25(OH)2D3 downregulates gene expression levels of muscle ubiquitin ligases MAFbx and MuRF1 in human myotubes
- (2015) Naohiko HAYAKAWA et al. BIOMEDICAL RESEARCH-TOKYO
- Relationship of anabolic and catabolic biomarkers with muscle strength and physical performance in older adults: a population-based cross-sectional study
- (2015) Yongxia Meng et al. BMC MUSCULOSKELETAL DISORDERS
- Sarcopenia as the Biological Substrate of Physical Frailty
- (2015) Francesco Landi et al. CLINICS IN GERIATRIC MEDICINE
- Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity
- (2015) Vanessa Pellegrinelli et al. DIABETES
- Vitamin C and E supplementation prevents some of the cellular adaptations to endurance-training in humans
- (2015) Dale Morrison et al. FREE RADICAL BIOLOGY AND MEDICINE
- FOXO1 Mediates Vitamin D Deficiency-Induced Insulin Resistance in Skeletal Muscle
- (2015) Songcang Chen et al. JOURNAL OF BONE AND MINERAL RESEARCH
- In vivolevels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice
- (2014) Angela Logan et al. AGING CELL
- Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for “inflamm-aging”
- (2014) Marcello Pinti et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Skeletal muscle capillary density and microvascular function are compromised with aging and type 2 diabetes
- (2014) Bart B. L. Groen et al. JOURNAL OF APPLIED PHYSIOLOGY
- The Effects of Vitamin D on Skeletal Muscle Strength, Muscle Mass, and Muscle Power: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- (2014) Charlotte Beaudart et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Vitamin C and E supplementation alters protein signalling after a strength training session, but not muscle growth during 10 weeks of training
- (2014) G. Paulsen et al. JOURNAL OF PHYSIOLOGY-LONDON
- Vitamin D Receptor Agonists: Suitable Candidates as Novel Therapeutic Options in Autoimmune Inflammatory Myopathy
- (2014) Clara Crescioli Biomed Research International
- Mitochondrial energetics is impairedin vivoin aged skeletal muscle
- (2013) Gilles Gouspillou et al. AGING CELL
- Secretome profiling of primary human skeletal muscle cells
- (2013) Sonja Hartwig et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation
- (2013) Brendan Egan et al. Cell Metabolism
- Effects of vitamin D in skeletal muscle: falls, strength, athletic performance and insulin sensitivity
- (2013) Christian M. Girgis et al. CLINICAL ENDOCRINOLOGY
- Abnormal protein turnover and anabolic resistance to exercise in sarcopenic obesity
- (2013) Mats I. Nilsson et al. FASEB JOURNAL
- Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword?
- (2013) Pura Muñoz-Cánoves et al. FEBS Journal
- Protective effect of whey protein hydrolysates on H2O2-induced PC12 cells oxidative stress via a mitochondria-mediated pathway
- (2013) Man-Man Jin et al. FOOD CHEMISTRY
- Redefining the major contributors to superoxide production in contracting skeletal muscle. The role of NAD(P)H oxidases
- (2013) G. K. Sakellariou et al. FREE RADICAL RESEARCH
- Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials
- (2013) Emanuele Marzetti et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome
- (2013) Marco Sandri INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Effects of prostaglandins and COX-inhibiting drugs on skeletal muscle adaptations to exercise
- (2013) Todd A. Trappe et al. JOURNAL OF APPLIED PHYSIOLOGY
- Vitamin D Receptor Inhibits Nuclear Factor κB Activation by Interacting with IκB Kinase β Protein
- (2013) Yunzi Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Vitamin D, Mitochondria, and Muscle
- (2013) Roger Bouillon et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Fatty acid metabolism, energy expenditure and insulin resistance in muscle
- (2013) Nigel Turner et al. JOURNAL OF ENDOCRINOLOGY
- Vitamin D Receptor Agonists Target CXCL10: New Therapeutic Tools for Resolution of Inflammation
- (2013) Sabino Scolletta et al. MEDIATORS OF INFLAMMATION
- The Vitamin D Receptor Agonist BXL-01-0029 as a Potential New Pharmacological Tool for the Treatment of Inflammatory Myopathies
- (2013) Luigi Di Luigi et al. PLoS One
- Vitamin C administration attenuates overload-induced skeletal muscle hypertrophy in rats
- (2012) Y. Makanae et al. Acta Physiologica
- Aging, Cellular Senescence, and Cancer
- (2012) Judith Campisi Annual Review of Physiology
- Studies of Mitochondrial and Nonmitochondrial Sources Implicate Nicotinamide Adenine Dinucleotide Phosphate Oxidase(s) in the Increased Skeletal Muscle Superoxide Generation That Occurs During Contractile Activity
- (2012) Giorgos Konstantinos Sakellariou et al. ANTIOXIDANTS & REDOX SIGNALING
- Cultured senescent myoblasts derived from human vastus lateralis exhibit normal mitochondrial ATP synthesis capacities with correlating concomitant ROS production while whole cell ATP production is decreased
- (2012) Ariane D. Minet et al. BIOGERONTOLOGY
- Vitamin D and Its Role in Skeletal Muscle
- (2012) Lisa Ceglia et al. CALCIFIED TISSUE INTERNATIONAL
- Increased ceramide content and NFκB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males
- (2012) Donato A. Rivas et al. JOURNAL OF APPLIED PHYSIOLOGY
- Muscles, exercise and obesity: skeletal muscle as a secretory organ
- (2012) Bente K. Pedersen et al. Nature Reviews Endocrinology
- Muscle-to-organ cross talk mediated by myokines
- (2012) Line Pedersen et al. Adipocyte
- Acute effects of whey protein isolate on blood pressure, vascular function and inflammatory markers in overweight postmenopausal women
- (2011) Sebely Pal et al. BRITISH JOURNAL OF NUTRITION
- Reduction in Reactive Oxygen Species Production by Mitochondria From Elderly Subjects With Normal and Impaired Glucose Tolerance
- (2011) S. Ghosh et al. DIABETES
- The role of ubiquitin–proteasome system in ageing
- (2011) Peter Löw GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Ectopic Lipid Accumulation and Reduced Glucose Tolerance in Elderly Adults Are Accompanied by Altered Skeletal Muscle Mitochondrial Activity
- (2011) Darcy L. Johannsen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Whey protein enhances normal inflammatory responses during cutaneous wound healing in diabetic rats
- (2011) Hossam Ebaid et al. Lipids in Health and Disease
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes: The Korean Sarcopenic Obesity Study (KSOS)
- (2010) T. N. Kim et al. DIABETES CARE
- Low-intensity physical activity is associated with reduced risk of incident type 2 diabetes in older adults: evidence from the English Longitudinal Study of Ageing
- (2010) P. Demakakos et al. DIABETOLOGIA
- Comparison between VDR analogs and current immunosuppressive drugs in relation to CXCL10 secretion by human renal tubular cells
- (2010) Costanza Sagrinati et al. TRANSPLANT INTERNATIONAL
- Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia
- (2009) Emilie A Wilkes et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Longitudinal study of muscle strength, quality, and adipose tissue infiltration
- (2009) et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Involvement of the vitamin D receptor in energy metabolism: regulation of uncoupling proteins
- (2009) Kari E. Wong et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy
- (2009) Emanuele Marzetti et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes
- (2009) S. W. Park et al. DIABETES CARE
- Higher Inflammatory Marker Levels in Older Persons: Associations With 5-Year Change in Muscle Mass and Muscle Strength
- (2009) L. A. Schaap et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The Chronic Effects of Whey Proteins on Blood Pressure, Vascular Function, and Inflammatory Markers in Overweight Individuals
- (2009) Sebely Pal et al. Obesity
- Effect of dietary protein content during recovery from high-intensity cycling on subsequent performance and markers of stress, inflammation, and muscle damage in well-trained men
- (2008) David S. Rowlands et al. Applied Physiology Nutrition and Metabolism
- Elocalcitol Inhibits Inflammatory Responses in Human Thyroid Cells and T Cells
- (2008) E. Borgogni et al. ENDOCRINOLOGY
- Immunomodulatory effects of BXL-01-0029, a less hypercalcemic vitamin D analogue, in human cardiomyocytes and T cells
- (2008) M. Sottili et al. EXPERIMENTAL CELL RESEARCH
- Nuclear factor-kappa B signaling in skeletal muscle atrophy
- (2008) Hong Li et al. JOURNAL OF MOLECULAR MEDICINE-JMM
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