Redefining the major contributors to superoxide production in contracting skeletal muscle. The role of NAD(P)H oxidases

Mitochondrial respiratory chain complex I is inactivated by NADPH oxidase Nox4

(2013) Rafał Kozieł et al.   BIOCHEMICAL JOURNAL

Evidence for novel aspects of Nox4 oxidase regulation of mitochondrial function and peroxide generation in an endothelial cell model of senescence

(2013) Michael S. Wolin   BIOCHEMICAL JOURNAL

Rac1 Signaling Is Required for Insulin-Stimulated Glucose Uptake and Is Dysregulated in Insulin-Resistant Murine and Human Skeletal Muscle

(2013) L. Sylow et al.   DIABETES

Studies of Mitochondrial and Nonmitochondrial Sources Implicate Nicotinamide Adenine Dinucleotide Phosphate Oxidase(s) in the Increased Skeletal Muscle Superoxide Generation That Occurs During Contractile Activity

(2012) Giorgos Konstantinos Sakellariou et al.   ANTIOXIDANTS & REDOX SIGNALING

Detection of reactive oxygen species derived from the family of NOX NADPH oxidases

(2012) Ghassan J. Maghzal et al.   FREE RADICAL BIOLOGY AND MEDICINE

X-ROS signaling in the heart and skeletal muscle: Stretch-dependent local ROS regulates [Ca2+]i

(2012) Benjamin L. Prosser et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Dihydropyridine receptors actively control gating of ryanodine receptors in resting mouse skeletal muscle fibres

(2012) Gaëlle Robin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Microtubules Underlie Dysfunction in Duchenne Muscular Dystrophy

(2012) R. J. Khairallah et al.   Science Signaling

Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase

(2011) Giorgos K. Sakellariou et al.   AGING CELL

Control of Reactive Oxygen Species Production in Contracting Skeletal Muscle

(2011) Malcolm J. Jackson   ANTIOXIDANTS & REDOX SIGNALING

Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals

(2011) Huaqiang Fang et al.   CELL RESEARCH

Glutathione Peroxidase-3 Deficiency Promotes Platelet-Dependent Thrombosis In Vivo

(2011) Richard C. Jin et al.   CIRCULATION

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

(2011) Ina Takac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria: isolation, structure and function

(2011) Martin Picard et al.   JOURNAL OF PHYSIOLOGY-LONDON

Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species

(2011) Malcolm J. Jackson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Targeting Mitochondrial Oxidative Stress in Heart Failure

(2011) Christoph Maack et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mitochondrial Targeted Antioxidant Peptide Ameliorates Hypertensive Cardiomyopathy

(2011) Dao-Fu Dai et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mitochondrial Structure and Function Are Disrupted by Standard Isolation Methods

(2011) Martin Picard et al.   PLoS One

Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4

(2011) Q.-A. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-ROS Signaling: Rapid Mechano-Chemo Transduction in Heart

(2011) B. L. Prosser et al.   SCIENCE

Hydrogen peroxide: a Jekyll and Hyde signalling molecule

(2011) D R Gough et al.   Cell Death & Disease

Decreased NADPH oxidase expression and antioxidant activity in cachectic skeletal muscle

(2011) Melanie J. Sullivan-Gunn et al.   Journal of Cachexia Sarcopenia and Muscle

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

(2010) Martin Picard et al.   AGING CELL

The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase

(2010) Aphrodite Vasilaki et al.   AGING CELL

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

(2010) Tetsuro Ago et al.   CIRCULATION RESEARCH

Mitochondrial redox potential during contraction in single intact muscle fibers

(2010) Luke P. Michaelson et al.   MUSCLE & NERVE

Superoxide Flashes in Mouse Skeletal Muscle Are Produced by Discrete Arrays of Active Mitochondria Operating Coherently

(2010) Sandrine Pouvreau   PLoS One

Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

(2010) Nicholas P. Whitehead et al.   PLoS One

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

(2010) J. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of xanthine oxidase-generated extracellular superoxide on skeletal muscle force generation

(2009) M. C. Gomez-Cabrera et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Redox regulation of adaptive responses in skeletal muscle to contractile activity

(2009) Malcolm J. Jackson   FREE RADICAL BIOLOGY AND MEDICINE

Phagocytic leukocytes and reactive oxygen species

(2009) John M. Robinson   HISTOCHEMISTRY AND CELL BIOLOGY

Redox regulation in skeletal muscle during contractile activity and aging 1

(2009) J. Palomero et al.   JOURNAL OF ANIMAL SCIENCE

The TOM complex is involved in the release of superoxide anion from mitochondria

(2009) Małgorzata Budzińska et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Subcellular localization of Nox4 and regulation in diabetes

(2009) K. Block et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thermal tolerance of contractile function in oxidative skeletal muscle: no protection by antioxidants and reduced tolerance with eicosanoid enzyme inhibition

(2008) S. Ryan Oliver et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

In Situ Detection and Measurement of Intracellular Reactive Oxygen Species in Single Isolated Mature Skeletal Muscle Fibers by Real Time Fluorescence Microscopy

(2008) Jesus Palomero et al.   ANTIOXIDANTS & REDOX SIGNALING

NADPH Oxidase-Dependent Signaling in Endothelial Cells: Role in Physiology and Pathophysiology

(2008) Randall S. Frey et al.   ANTIOXIDANTS & REDOX SIGNALING

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

The production of reactive oxygen species by complex I

(2008) Judy Hirst et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Superoxide Flashes in Single Mitochondria

(2008) Wang Wang et al.   CELL

Reactive oxygen species in phagocytic leukocytes

(2008) John M. Robinson   HISTOCHEMISTRY AND CELL BIOLOGY

Increased mitochondrial Ca 2+ and decreased sarcoplasmic reticulum Ca 2+ in mitochondrial myopathy

(2008) Jan Aydin et al.   HUMAN MOLECULAR GENETICS

NADPH Oxidase and Hydrogen Peroxide Mediate Insulin-induced Calcium Increase in Skeletal Muscle Cells

(2008) Alejandra Espinosa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apocynin: Molecular Aptitudes

(2008) J. Stefanska et al.   MEDIATORS OF INFLAMMATION

Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production

(2008) Scott K. Powers et al.   PHYSIOLOGICAL REVIEWS

Regulation of Proliferation of Skeletal Muscle Precursor Cells By NADPH Oxidase

(2007) Mahroo Mofarrahi et al.   ANTIOXIDANTS & REDOX SIGNALING

Free radicals generated by contracting muscle: By-products of metabolism or key regulators of muscle function?

(2007) Malcolm J. Jackson   FREE RADICAL BIOLOGY AND MEDICINE

Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

(2007) Sabine Heumüller et al.   HYPERTENSION