Fatty acid metabolism, energy expenditure and insulin resistance in muscle

O-GlcNAc Cycling: A Link Between Metabolism and Chronic Disease

(2013) Michelle R. Bond et al.   Annual Review of Nutrition

Muscle insulin resistance resulting from impaired microvascular insulin sensitivity in Sprague Dawley rats

(2013) Dino Premilovac et al.   CARDIOVASCULAR RESEARCH

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

(2013) Sean J. Humphrey et al.   Cell Metabolism

Circadian Disruption Leads to Insulin Resistance and Obesity

(2013) Shu-qun Shi et al.   CURRENT BIOLOGY

Mitochondrial Respiratory Capacity and Content Are Normal in Young Insulin-Resistant Obese Humans

(2013) K. H. Fisher-Wellman et al.   DIABETES

Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects

(2013) K. T. Tonks et al.   DIABETOLOGIA

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

(2013) N. Turner et al.   DIABETOLOGIA

Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding

(2013) M. K. Montgomery et al.   DIABETOLOGIA

Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity

(2013) Claudia P. Coomans et al.   FASEB JOURNAL

Adaptive thermogenesis in adipocytes: Is beige the new brown?

(2013) J. Wu et al.   GENES & DEVELOPMENT

Mitochondrial energetic metabolism-some general principles

(2013) Jean-Pierre Mazat et al.   IUBMB LIFE

Slow-Twitch Fiber Proportion in Skeletal Muscle Correlates With Insulin Responsiveness

(2013) Charles A. Stuart et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Changes in the Energy Cost of Running during a 24-h Treadmill Exercise

(2013) Philippe Gimenez et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

(2013) Jeongsoon Park et al.   MOLECULAR CELL

Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation

(2013) Zhuo-Xian Meng et al.   NATURE MEDICINE

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity

(2013) Martin J. J. Ronis et al.   PHYSIOLOGICAL GENOMICS

Chronic Treatment with the AMP-Kinase Activator AICAR Increases Glycogen Storage and Fatty Acid Oxidation in Skeletal Muscles but Does Not Reduce Hyperglucagonemia and Hyperglycemia in Insulin Deficient Rats

(2013) Kaio F. Vitzel et al.   PLoS One

Cracking the O-GlcNAc code in metabolism

(2013) Hai-Bin Ruan et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet

(2012) Erin J. Stephenson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PET imaging reveals distinctive roles for different regional adipose tissue depots in systemic glucose metabolism in nonobese humans

(2012) Jason M. Ng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle

(2012) Michael J. Boden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Prolonged exercise training increases intramuscular lipid content and perilipin 2 expression in type I muscle fibers of patients with type 2 diabetes

(2012) C. S. Shaw et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Combination of fucoxanthin and conjugated linoleic acid attenuates body weight gain and improves lipid metabolism in high-fat diet-induced obese rats

(2012) Xiaojie Hu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice

(2012) W. Keung et al.   DIABETES

Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice

(2012) D. C. Henstridge et al.   DIABETOLOGIA

Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans

(2012) B. C. Bergman et al.   DIABETOLOGIA

The Sphingosine-1-Phosphate Analog FTY720 Reduces Muscle Ceramide Content and Improves Glucose Tolerance in High Fat-Fed Male Mice

(2012) Clinton R. Bruce et al.   ENDOCRINOLOGY

Quantitative analysis of light-phase restricted feeding reveals metabolic dyssynchrony in mice

(2012) M S Bray et al.   INTERNATIONAL JOURNAL OF OBESITY

Mitochondrial Protein Acylation and Intermediary Metabolism: Regulation by Sirtuins and Implications for Metabolic Disease

(2012) John C. Newman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GLUT4 exocytosis

(2012) Jacqueline Stöckli et al.   JOURNAL OF CELL SCIENCE

Physical Activity Is the Key Determinant of Skeletal Muscle Mitochondrial Function in Type 2 Diabetes

(2012) F. H. J. van Tienen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity

(2012) Hayley M. O’Neill et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Nuclear Receptor, Nor-1, Markedly Increases Type II Oxidative Muscle Fibers and Resistance to Fatigue

(2012) Michael A. Pearen et al.   MOLECULAR ENDOCRINOLOGY

Circadian topology of metabolism

(2012) Joseph Bass   NATURE

Obesity in mice with adipocyte-specific deletion of clock component Arntl

(2012) Georgios K Paschos et al.   NATURE MEDICINE

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity

(2012) S. Timmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of intramyocelluar lipids in human health

(2012) Paul M. Coen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Linking mitochondrial bioenergetics to insulin resistance via redox biology

(2012) Kelsey H. Fisher-Wellman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Regulation of Hepatic Glucose Uptake and Storage In Vivo

(2012) Mary Courtney Moore et al.   Advances in Nutrition

Obesity augments the age-induced increase in mitochondrial capacity for H2O2 release in Zucker fatty rats

(2011) M. Hey-Mogensen et al.   Acta Physiologica

Lipid metabolism in skeletal muscle: generation of adaptive and maladaptive intracellular signals for cellular function

(2011) Matthew J. Watt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Inhibition of lipolysis in Type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates

(2011) Ee L. Lim et al.   CLINICAL SCIENCE

Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet-Induced Insulin Resistance

(2011) Y. S. Lee et al.   DIABETES

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

(2011) F. Amati et al.   DIABETES

Brain glucose sensing and neural regulation of insulin and glucagon secretion

(2011) B. Thorens   DIABETES OBESITY & METABOLISM

The role of lipid droplets in metabolic disease in rodents and humans

(2011) Andrew S. Greenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Re-evaluating lipotoxic triggers in skeletal muscle: Relating intramyocellular lipid metabolism to insulin sensitivity

(2011) Madeleen Bosma et al.   PROGRESS IN LIPID RESEARCH

Obesity-associated insulin resistance in skeletal muscle: Role of lipid accumulation and physical inactivity

(2011) Kristin Eckardt et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

GLP-1 treatment reduces endogenous insulin resistance via activation of central GLP-1 receptors in mice fed a high-fat diet

(2010) Edwin T. Parlevliet et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Nitrosative modifications of protein and lipid signaling molecules by reactive nitrogen species

(2010) Phillip J. White et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Acute or Chronic Upregulation of Mitochondrial Fatty Acid Oxidation Has No Net Effect on Whole-Body Energy Expenditure or Adiposity

(2010) Kyle L. Hoehn et al.   Cell Metabolism

Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle

(2010) Michale Bouskila et al.   Cell Metabolism

Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

(2010) J. Hoeks et al.   DIABETES

Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle

(2010) N. Lefort et al.   DIABETES

A Recurring Problem With the Analysis of Energy Expenditure in Genetic Models Expressing Lean and Obese Phenotypes

(2010) A. A. Butler et al.   DIABETES

Loss of insulin-mediated microvascular perfusion in skeletal muscle is associated with the development of insulin resistance

(2010) P. St-Pierre et al.   DIABETES OBESITY & METABOLISM

A family history of type 2 diabetes increases risk factors associated with overfeeding

(2010) D. Samocha-Bonet et al.   DIABETOLOGIA

Chronic Prednisolone Treatment Reduces Hepatic Insulin Sensitivity while Perturbing the Fed-to-Fasting Transition in Mice

(2010) Anke J. Laskewitz et al.   ENDOCRINOLOGY

The physiological regulation of glucose flux into muscle in vivo

(2010) D. H. Wasserman et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Membrane Fatty Acid Transporters as Regulators of Lipid Metabolism: Implications for Metabolic Disease

(2010) Jan F. C. Glatz et al.   PHYSIOLOGICAL REVIEWS

Osteopontin Is Required for the Early Onset of High Fat Diet-Induced Insulin Resistance in Mice

(2010) Justin Chapman et al.   PLoS One

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

(2010) D. P. Olson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-chain polyunsaturated fatty acids: Selected mechanisms of action on bone

(2010) M.C. Kruger et al.   PROGRESS IN LIPID RESEARCH

NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse

(2009) Owen P. McGuinness et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation

(2009) Andrew J. Hoy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Randle cycle revisited: a new head for an old hat

(2009) Louis Hue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity

(2009) Vladimir B. Ritov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Green Tea (–)-Epigallocatechin-3-Gallate Reduces Body Weight with Regulation of Multiple Genes Expression in Adipose Tissue of Diet-Induced Obese Mice

(2009) Mak-Soon Lee et al.   ANNALS OF NUTRITION AND METABOLISM

Proteomics Analysis of Human Skeletal Muscle Reveals Novel Abnormalities in Obesity and Type 2 Diabetes

(2009) H. Hwang et al.   DIABETES

The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity

(2009) I Akpan et al.   INTERNATIONAL JOURNAL OF OBESITY

Electron Transport Chain-dependent and -independent Mechanisms of Mitochondrial H2O2Emission during Long-chain Fatty Acid Oxidation

(2009) Erin L. Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Examination of ‘lipotoxicity’ in skeletal muscle of high-fat fed andob/obmice

(2009) S. M. Turpin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Insulin resistance is a cellular antioxidant defense mechanism

(2009) K. L. Hoehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluating the glucose tolerance test in mice

(2008) Sofianos Andrikopoulos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Four grams of glucose

(2008) David H. Wasserman   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Efficiency of Cellular Energy Transduction and Its Implications for Obesity

(2008) Mary-Ellen Harper et al.   Annual Review of Nutrition

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice

(2008) Yasuhiro Izumiya et al.   Cell Metabolism

IRS1-Independent Defects Define Major Nodes of Insulin Resistance

(2008) Kyle L. Hoehn et al.   Cell Metabolism

Role of Mitochondrial Dysfunction in Insulin Resistance

(2008) Jeong-a Kim et al.   CIRCULATION RESEARCH

Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet-Induced Insulin Resistance

(2008) C. R. Bruce et al.   DIABETES

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

(2008) E. Phielix et al.   DIABETES

Increased Daily Walking Improves Lipid Oxidation Without Changes in Mitochondrial Function in Type 2 Diabetes

(2008) M. I. Trenell et al.   DIABETES CARE

Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity

(2008) M. Skovbro et al.   DIABETOLOGIA

Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle mitochondrial dysfunction

(2008) H M De Feyter et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Acute elevation of circulating fatty acids impairs downstream insulin signalling in rat skeletal muscle in vivo independent of effects on stress signalling

(2008) Georgia Frangioudakis et al.   JOURNAL OF ENDOCRINOLOGY

Paradoxical effects of increased expression of PGC-1  on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

(2008) C. S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-fat diets cause insulin resistance despite an increase in muscle mitochondria

(2008) C. R. Hancock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is mitochondrial dysfunction a cause of insulin resistance?

(2008) Nigel Turner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Postburn trauma insulin resistance and fat metabolism

(2007) Melanie G. Cree et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Effects of short-term very low-calorie diet on intramyocellular lipid and insulin sensitivity in nondiabetic and type 2 diabetic subjects

(2007) Cristina Lara-Castro et al.   METABOLISM-CLINICAL AND EXPERIMENTAL