Evolutionary History of the Toll-Like Receptor Gene Family across Vertebrates

Toll‐like receptor polymorphism in host immune response to infectious diseases: A review

(2019) Suprabhat Mukherjee et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Non-mammalian Toll-like receptor 18 (Tlr18) recognizes bacterial pathogens in common carp ( Cyprinus carpio L.): Indications for a role of participation in the NF-κB signaling pathway

(2018) Shijuan Shan et al.   FISH & SHELLFISH IMMUNOLOGY

Toll-Like Receptor Evolution in Birds: Gene Duplication, Pseudogenization, and Diversifying Selection

(2018) Hana Velová et al.   MOLECULAR BIOLOGY AND EVOLUTION

Evolutionary Origins of Toll-like Receptor Signaling

(2018) Joseph J Brennan et al.   MOLECULAR BIOLOGY AND EVOLUTION

Signatures of balancing selection in toll-like receptor (TLRs) genes – novel insights from a free-living rodent

(2018) Agnieszka Kloch et al.   Scientific Reports

The evolution of immunity in relation to colonization and migration

(2018) Emily A. O’Connor et al.   Nature Ecology & Evolution

Teleost-specific TLR25 identified from Schizothorax prenanti may recognize bacterial/viral components and activate NF-κB and type I IFNs signaling pathways

(2018) Yunkun Li et al.   FISH & SHELLFISH IMMUNOLOGY

The Pandemic Threat of Emerging H5 and H7 Avian Influenza Viruses

(2018) Troy Sutton   Viruses-Basel

Characterization of the TLR Family in Branchiostoma lanceolatum and Discovery of a Novel TLR22-Like Involved in dsRNA Recognition in Amphioxus

(2018) Jie Ji et al.   Frontiers in Immunology

Teleost-Specific TLR19 Localizes to Endosome, Recognizes dsRNA, Recruits TRIF, Triggers both IFN and NF-κB Pathways, and Protects Cells from Grass Carp Reovirus Infection

(2017) Jianfei Ji et al.   JOURNAL OF IMMUNOLOGY

Programmatic access to bioinformatics tools from EMBL-EBI update: 2017

(2017) Szymon Chojnacki et al.   NUCLEIC ACIDS RESEARCH

20 years of the SMART protein domain annotation resource

(2017) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

Toll-like receptor pathway evolution in deuterostomes

(2017) Michael G. Tassia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A conserved TLR5 binding and activation hot spot on flagellin

(2017) Wan Seok Song et al.   Scientific Reports

CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses

(2017) Da-Wei Yeh et al.   Scientific Reports

Introgression of Neandertal- and Denisovan-like Haplotypes Contributes to Adaptive Variation in Human Toll-like Receptors

(2016) Michael Dannemann et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes

(2016) Matthieu Deschamps et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Toll Genes Have an Ancestral Role in Axis Elongation

(2016) Matthew A. Benton et al.   CURRENT BIOLOGY

Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA

(2016) Zhikuan Zhang et al.   IMMUNITY

Visual Pigments, Ocular Filters and the Evolution of Snake Vision

(2016) Bruno F. Simões et al.   MOLECULAR BIOLOGY AND EVOLUTION

Ectodomain Architecture Affects Sequence and Functional Evolution of Vertebrate Toll-like Receptors

(2016) Jinlan Wang et al.   Scientific Reports

Immune Responses in Cecal Tonsils of Marek's Disease Virus–Infected Chickens

(2015) Mohammad Heidari et al.   AVIAN DISEASES

Hemichordate genomes and deuterostome origins

(2015) Oleg Simakov et al.   NATURE

Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

(2015) Umeharu Ohto et al.   NATURE

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Toll-like receptor 8 senses degradation products of single-stranded RNA

(2015) Hiromi Tanji et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Toll-like receptor 8 senses degradation products of single-stranded RNA

(2015) Hiromi Tanji et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Advantageous diversity maintained by balancing selection in humans

(2014) Felix M Key et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

First evidence of independent pseudogenization of Toll-like receptor 5 in passerine birds

(2014) Hana Bainová et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Constraint and Adaptation in newt Toll-Like Receptor Genes

(2014) Wiesław Babik et al.   Genome Biology and Evolution

Balancing Selection Is the Main Force Shaping the Evolution of Innate Immunity Genes

(2014) A. Ferrer-Admetlla et al.   JOURNAL OF IMMUNOLOGY

Episodic Positive Selection in the Evolution of Avian Toll-Like Receptor Innate Immunity Genes

(2014) Catherine E. Grueber et al.   PLoS One

Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

(2014) H. Laayouni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative genomics reveals insights into avian genome evolution and adaptation

(2014) G. Zhang et al.   SCIENCE

Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations

(2013) Hélène Quach et al.   HUMAN MOLECULAR GENETICS

Identification and functional characterization of nonmammalian Toll-like receptor 20

(2013) Danilo Pietretti et al.   IMMUNOGENETICS

Cooperation of TLR12 and TLR11 in the IRF8-Dependent IL-12 Response to Toxoplasma gondii Profilin

(2013) M. Raetz et al.   JOURNAL OF IMMUNOLOGY

FUBAR: A Fast, Unconstrained Bayesian AppRoximation for Inferring Selection

(2013) B. Murrell et al.   MOLECULAR BIOLOGY AND EVOLUTION

De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis

(2013) Brian J Haas et al.   Nature Protocols

Adaptive evolution and functional constraint at TLR4 during the secondary aquatic adaptation and diversification of cetaceans

(2012) Tong Shen et al.   BMC EVOLUTIONARY BIOLOGY

Recognition of Profilin by Toll-like Receptor 12 Is Critical for Host Resistance to Toxoplasma gondii

(2012) A. Alicia Koblansky et al.   IMMUNITY

TLR15 Is Unique to Avian and Reptilian Lineages and Recognizes a Yeast-Derived Agonist

(2012) A. C. Boyd et al.   JOURNAL OF IMMUNOLOGY

Insights into bilaterian evolution from three spiralian genomes

(2012) Oleg Simakov et al.   NATURE

Genomic insights into the marine sponge microbiome

(2012) Ute Hentschel et al.   NATURE REVIEWS MICROBIOLOGY

Variation at Innate Immunity Toll-Like Receptor Genes in a Bottlenecked Population of a New Zealand Robin

(2012) Catherine E. Grueber et al.   PLoS One

TLR13 Recognizes Bacterial 23S rRNA Devoid of Erythromycin Resistance-Forming Modification

(2012) M. Oldenburg et al.   SCIENCE

Global Gradients in Vertebrate Diversity Predicted by Historical Area-Productivity Dynamics and Contemporary Environment

(2012) Walter Jetz et al.   PLOS BIOLOGY

Sequence specific detection of bacterial 23S ribosomal RNA by TLR13

(2012) Xiao-Dong Li et al.   eLife

SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler

(2012) Ruibang Luo et al.   GigaScience

Signatures of positive selection in Toll-like receptor (TLR) genes in mammals

(2011) Helena Areal et al.   BMC EVOLUTIONARY BIOLOGY

Molecular Evolution of the Toll-Like Receptor Multigene Family in Birds

(2011) M. Alcaide et al.   MOLECULAR BIOLOGY AND EVOLUTION

Animal Migration and Infectious Disease Risk

(2011) S. Altizer et al.   SCIENCE

LRRfinder: A web application for the identification of leucine-rich repeats and an integrative Toll-like receptor database

(2010) V. Offord et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The genome of the sponge Amphimedon queenslandica provides new perspectives into the origin of Toll-like and interleukin 1 receptor pathways

(2010) Marie E. A. Gauthier et al.   EVOLUTION & DEVELOPMENT

Molecular cloning and characterization of Toll-like receptor 14 in Japanese flounder, Paralichthys olivaceus

(2010) Seong Don Hwang et al.   FISH & SHELLFISH IMMUNOLOGY

Dimerization of Toll-like Receptor 3 (TLR3) Is Required for Ligand Binding

(2010) Yan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adaptation and Constraint at Toll-Like Receptors in Primates

(2010) G. Wlasiuk et al.   MOLECULAR BIOLOGY AND EVOLUTION

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

(2010) Su-Chang Lin et al.   NATURE

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Association between Toll-like receptor 2 (TLR2) polymorphisms and asymptomatic bancroftian filariasis

(2010) Alisa Junpee et al.   PARASITOLOGY RESEARCH

Human and Non-Human Primate Genomes Share Hotspots of Positive Selection

(2010) David Enard et al.   PLoS Genetics

SeaView Version 4: A Multiplatform Graphical User Interface for Sequence Alignment and Phylogenetic Tree Building

(2009) M. Gouy et al.   MOLECULAR BIOLOGY AND EVOLUTION

Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides

(2009) Robert Brownlie et al.   MOLECULAR IMMUNOLOGY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains

(2009) Tiandi Wei et al.   PROTEIN SCIENCE

Variation matters: TLR structure and species-specific pathogen recognition

(2009) Dirk Werling et al.   TRENDS IN IMMUNOLOGY

Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

(2009) Luis B. Barreiro et al.   PLoS Genetics

Genomic analysis of the immune gene repertoire of amphioxus reveals extraordinary innate complexity and diversity

(2008) S. Huang et al.   GENOME RESEARCH

Toll-like receptors — taking an evolutionary approach

(2008) François Leulier et al.   NATURE REVIEWS GENETICS

Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

(2008) L. Liu et al.   SCIENCE