Adaptation and Constraint at Toll-Like Receptors in Primates

Balancing Selection Is the Main Force Shaping the Evolution of Innate Immunity Genes

(2014) A. Ferrer-Admetlla et al.   JOURNAL OF IMMUNOLOGY

Pathogen recognition in the innate immune response

(2009) Himanshu Kumar et al.   BIOCHEMICAL JOURNAL

DnaSP v5: a software for comprehensive analysis of DNA polymorphism data

(2009) P. Librado et al.   BIOINFORMATICS

Polymorphism N248S in the Human Toll‐Like Receptor 1 Gene Is Related to Leprosy and Leprosy Reactions

(2009) Ron P. Schuring et al.   JOURNAL OF INFECTIOUS DISEASES

A History of Recurrent Positive Selection at the Toll-Like Receptor 5 in Primates

(2009) Gabriela Wlasiuk et al.   MOLECULAR BIOLOGY AND EVOLUTION

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Signatures of natural selection are not uniform across genes of innate immune system, but purifying selection is the dominant signature

(2009) S. Mukherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains

(2009) Tiandi Wei et al.   PROTEIN SCIENCE

Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

(2009) Luis B. Barreiro et al.   PLoS Genetics

The evolutionary history of the CD209 (DC-SIGN) family in humans and non-human primates

(2008) M Ortiz et al.   GENES AND IMMUNITY

Natural selection in the TLR-related genes in the course of primate evolution

(2008) Toshiaki Nakajima et al.   IMMUNOGENETICS

Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk

(2008) Victoria L. Stevens et al.   INTERNATIONAL JOURNAL OF CANCER

Protein kinase R reveals an evolutionary model for defeating viral mimicry

(2008) Nels C. Elde et al.   NATURE

Proportionally more deleterious genetic variation in European than in African populations

(2008) Kirk E. Lohmueller et al.   NATURE

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE

Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

(2008) L. Liu et al.   SCIENCE