Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

Balancing Selection Is the Main Force Shaping the Evolution of Innate Immunity Genes

(2014) A. Ferrer-Admetlla et al.   JOURNAL OF IMMUNOLOGY

A Genome-wide Survey of the Prevalence and Evolutionary Forces Acting on Human Nonsense SNPs

(2009) Bryndis Yngvadottir et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A History of Recurrent Positive Selection at the Toll-Like Receptor 5 in Primates

(2009) Gabriela Wlasiuk et al.   MOLECULAR BIOLOGY AND EVOLUTION

Signatures of natural selection are not uniform across genes of innate immune system, but purifying selection is the dominant signature

(2009) S. Mukherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural selection on the Drosophila antimicrobial immune system

(2008) Brian P Lazzaro   CURRENT OPINION IN MICROBIOLOGY

Natural selection has driven population differentiation in modern humans

(2008) Luis B Barreiro et al.   NATURE GENETICS

Toll-like receptors — taking an evolutionary approach

(2008) François Leulier et al.   NATURE REVIEWS GENETICS

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE

Human TLR1 Deficiency Is Associated with Impaired Mycobacterial Signaling and Protection from Leprosy Reversal Reaction

(2008) Elizabeth A. Misch et al.   PLoS Neglected Tropical Diseases