How enzyme promiscuity and horizontal gene transfer contribute to metabolic innovation
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Title
How enzyme promiscuity and horizontal gene transfer contribute to metabolic innovation
Authors
Keywords
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Journal
FEBS Journal
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-12-20
DOI
10.1111/febs.15185
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Note: Only part of the references are listed.- Enzyme promiscuity shapes adaptation to novel growth substrates
- (2019) Gabriela I Guzmán et al. Molecular Systems Biology
- Metabolite–Enzyme Coevolution: From Single Enzymes to Metabolic Pathways and Networks
- (2018) Lianet Noda-Garcia et al. Annual Review of Biochemistry
- Comparison of Alicyclobacillus acidocaldarius o-Succinylbenzoate Synthase to Its Promiscuous N-Succinylamino Acid Racemase/o-Succinylbenzoate Synthase Relatives
- (2018) Denis Odokonyero et al. BIOCHEMISTRY
- Underground metabolism: network-level perspective and biotechnological potential
- (2018) Richard A Notebaart et al. CURRENT OPINION IN BIOTECHNOLOGY
- A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function
- (2018) Jon Jerlström Hultqvist et al. Nature Ecology & Evolution
- Reframing gene essentiality in terms of adaptive flexibility
- (2018) Gabriela I. Guzmán et al. BMC Systems Biology
- Metabolic repair through emergence of new pathways in Escherichia coli
- (2018) Sammy Pontrelli et al. Nature Chemical Biology
- A two-step evolutionary process establishes a non-native vitamin B6 pathway in Bacillus subtilis
- (2017) Jonathan Rosenberg et al. ENVIRONMENTAL MICROBIOLOGY
- Primordial-like enzymes from bacteria with reduced genomes
- (2017) Matteo P. Ferla et al. MOLECULAR MICROBIOLOGY
- Structural and functional innovations in the real-time evolution of new (βα)8barrel enzymes
- (2017) Matilda S. Newton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identical Active Sites in Hydroxynitrile Lyases Show Opposite Enantioselectivity and Reveal Possible Ancestral Mechanism
- (2017) Bryan J. Jones et al. ACS Catalysis
- Evolution of substrate specificity in a retained enzyme driven by gene loss
- (2017) Ana Lilia Juárez-Vázquez et al. eLife
- Members of a Novel Kinase Family (DUF1537) Can Recycle Toxic Intermediates into an Essential Metabolite
- (2016) Jennifer J. Thiaville et al. ACS Chemical Biology
- Co-occurrence of analogous enzymes determines evolution of a novel ( )8-isomerase sub-family after non-conserved mutations in flexible loop
- (2016) E. A. Verduzco-Castro et al. BIOCHEMICAL JOURNAL
- Promiscuity and electrostatic flexibility in the alkaline phosphatase superfamily
- (2016) Anna Pabis et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Comparison of the complete genome sequences of four γ-hexachlorocyclohexane-degrading bacterial strains: insights into the evolution of bacteria able to degrade a recalcitrant man-made pesticide
- (2016) Michiro Tabata et al. DNA RESEARCH
- Catalytic Promiscuity of Ancestral Esterases and Hydroxynitrile Lyases
- (2016) Titu Devamani et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars
- (2016) Xinshuai Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gradual neofunctionalization in the convergent evolution of trichomonad lactate and malate dehydrogenases
- (2016) Phillip A. Steindel et al. PROTEIN SCIENCE
- Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation
- (2016) Maximilian G. Plach et al. PLoS Genetics
- Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity
- (2016) Miriam Kaltenbach et al. PLoS Genetics
- Insights into the evolution of enzyme substrate promiscuity after the discovery of (βα)8 isomerase evolutionary intermediates from a diverse metagenome
- (2015) Lianet Noda-García et al. BMC EVOLUTIONARY BIOLOGY
- Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegans
- (2015) James C. Farslow et al. BMC GENOMICS
- Evolution of a Catalytic Mechanism
- (2015) Alissa Rauwerdink et al. MOLECULAR BIOLOGY AND EVOLUTION
- Model-driven discovery of underground metabolic functions inEscherichia coli
- (2015) Gabriela I. Guzmán et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Panoramic view of a superfamily of phosphatases through substrate profiling
- (2015) Hua Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An evolutionary biochemist's perspective on promiscuity
- (2015) Shelley D. Copley TRENDS IN BIOCHEMICAL SCIENCES
- Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics
- (2015) Pierre-Yves Colin et al. Nature Communications
- Insights into Ongoing Evolution of the Hexachlorocyclohexane Catabolic Pathway from Comparative Genomics of Ten Sphingomonadaceae Strains
- (2015) S. L. Pearce et al. G3-Genes Genomes Genetics
- Promiscuity of Exiguobacterium sp. AT1b o-succinylbenzoate synthase illustrates evolutionary transitions in the OSBS family
- (2014) Ashley M. Brizendine et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A substrate ambiguous enzyme facilitates genome reduction in an intracellular symbiont
- (2014) Daniel RG Price et al. BMC BIOLOGY
- Enzyme Promiscuity: Engine of Evolutionary Innovation
- (2014) Chetanya Pandya et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Escherichia colid-Malate Dehydrogenase, a Generalist Enzyme Active in the Leucine Biosynthesis Pathway
- (2014) Anastassia A. Vorobieva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High Fitness Costs and Instability of Gene Duplications Reduce Rates of Evolution of New Genes by Duplication-Divergence Mechanisms
- (2014) M. Adler et al. MOLECULAR BIOLOGY AND EVOLUTION
- A Comprehensive, High-Resolution Map of a Gene’s Fitness Landscape
- (2014) Elad Firnberg et al. MOLECULAR BIOLOGY AND EVOLUTION
- Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family
- (2014) D. Odokonyero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Network-level architecture and the evolutionary potential of underground metabolism
- (2014) R. A. Notebaart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Promiscuous and Adaptable Enzymes Fill "Holes" in the Tetrahydrofolate Pathway in Chlamydia Species
- (2014) N. E. Adams et al. mBio
- Identification of promiscuous ene-reductase activity by mining structural databases using active site constellations
- (2014) Georg Steinkellner et al. Nature Communications
- Characterization of serine hydroxymethyltransferase GlyA as a potential source of D-alanine in Chlamydia pneumoniae
- (2014) Stefania De Benedetti et al. Frontiers in Cellular and Infection Microbiology
- Molecular annotation of ketol-acid reductoisomerases fromStreptomycesreveals a novel amino acid biosynthesis interlock mediated by enzyme promiscuity
- (2014) Karina Verdel-Aranda et al. Microbial Biotechnology
- Flexibility and Reactivity in Promiscuous Enzymes
- (2013) Pietro Gatti-Lafranconi et al. CHEMBIOCHEM
- Evolution of Substrate Specificity in a Recipient’s Enzyme Following Horizontal Gene Transfer
- (2013) Lianet Noda-García et al. MOLECULAR BIOLOGY AND EVOLUTION
- Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol
- (2013) I. Yadid et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pentachlorophenol Hydroxylase, a Poorly Functioning Enzyme Required for Degradation of Pentachlorophenol by Sphingobium chlorophenolicum
- (2012) Klara Hlouchova et al. BIOCHEMISTRY
- Enzyme functional evolution through improved catalysis of ancestrally nonpreferred substrates
- (2012) R. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A sugar isomerization reaction established on various ( )8-barrel scaffolds is based on substrate-assisted catalysis
- (2012) B. Reisinger et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence
- (2012) J. Nasvall et al. SCIENCE
- Reconstruction of Ancestral Metabolic Enzymes Reveals Molecular Mechanisms Underlying Evolutionary Innovation through Gene Duplication
- (2012) Karin Voordeckers et al. PLOS BIOLOGY
- Role of Chemistry versus Substrate Binding in Recruiting Promiscuous Enzyme Functions
- (2011) Olga Khersonsky et al. BIOCHEMISTRY
- The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters
- (2011) Arren Bar-Even et al. BIOCHEMISTRY
- Trends and barriers to lateral gene transfer in prokaryotes
- (2011) Ovidiu Popa et al. CURRENT OPINION IN MICROBIOLOGY
- The Whole Genome Sequence of Sphingobium chlorophenolicum L-1: Insights into the Evolution of the Pentachlorophenol Degradation Pathway
- (2011) Shelley D. Copley et al. Genome Biology and Evolution
- Lateral Transfer of Genes and Gene Fragments in Staphylococcus Extends beyond Mobile Elements
- (2011) C. X. Chan et al. JOURNAL OF BACTERIOLOGY
- The family of terpene synthases in plants: a mid-size family of genes for specialized metabolism that is highly diversified throughout the kingdom
- (2011) Feng Chen et al. PLANT JOURNAL
- Bisubstrate specificity in histidine/tryptophan biosynthesis isomerase fromMycobacterium tuberculosisby active site metamorphosis
- (2011) Anne V. Due et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Horizontal Transfer, Not Duplication, Drives the Expansion of Protein Families in Prokaryotes
- (2011) Todd J. Treangen et al. PLoS Genetics
- Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective
- (2010) Olga Khersonsky and Dan S. Tawfik Annual Review of Biochemistry
- What makes an enzyme promiscuous?
- (2010) Ann Babtie et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation
- (2010) Maria Pränting et al. MOLECULAR MICROBIOLOGY
- Compensatory gene amplification restores fitness after inter-species gene replacements
- (2010) Peter A. Lind et al. MOLECULAR MICROBIOLOGY
- Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5′-phosphate synthesis
- (2010) Juhan Kim et al. Molecular Systems Biology
- The evolution of gene duplications: classifying and distinguishing between models
- (2010) Hideki Innan et al. NATURE REVIEWS GENETICS
- Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli
- (2010) V. W. C. Soo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification and analysis of residues contained on β → α loops of the dual-substrate (βα)8phosphoribosyl isomerase A specific for its phosphoribosyl anthranilate isomerase activity
- (2010) Lianet Noda-García et al. PROTEIN SCIENCE
- A genome-wide analysis of nonribosomal peptide synthetase gene clusters and their peptides in a Planktothrix rubescens strain
- (2009) Trine B Rounge et al. BMC GENOMICS
- Distinguishing Among Evolutionary Models for the Maintenance of Gene Duplicates
- (2009) M. W. Hahn JOURNAL OF HEREDITY
- Evidence for escape from adaptive conflict?
- (2009) Todd Barkman et al. NATURE
- Ohno's Model Revisited: Measuring the Frequency of Potentially Adaptive Mutations under Various Mutational Drifts
- (2008) Shimon Bershtein et al. MOLECULAR BIOLOGY AND EVOLUTION
- Escape from adaptive conflict after duplication in an anthocyanin pathway gene
- (2008) David L. Des Marais et al. NATURE
- Turning a hobby into a job: How duplicated genes find new functions
- (2008) Gavin C. Conant et al. NATURE REVIEWS GENETICS
- An Alternative Menaquinone Biosynthetic Pathway Operating in Microorganisms
- (2008) T. Hiratsuka et al. SCIENCE
- The structure/function relationship of a dual-substrate (βα)8-isomerase
- (2007) Helena Wright et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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