A substrate ambiguous enzyme facilitates genome reduction in an intracellular symbiont

The Tiniest Tiny Genomes

(2014) Nancy A. Moran et al.   Annual Review of Microbiology

Parallel Histories of Horizontal Gene Transfer Facilitated Extreme Reduction of Endosymbiont Genomes in Sap-Feeding Insects

(2014) Daniel B. Sloan et al.   MOLECULAR BIOLOGY AND EVOLUTION

Network-level architecture and the evolutionary potential of underground metabolism

(2014) R. A. Notebaart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Promiscuous and Adaptable Enzymes Fill "Holes" in the Tetrahydrofolate Pathway in Chlamydia Species

(2014) N. E. Adams et al.   mBio

Shared Metabolic Pathways in a Coevolved Insect-Bacterial Symbiosis

(2013) Calum W. Russell et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Comparative analysis of genome sequences from four strains of the Buchnera aphidicola Mp endosymbion of the green peach aphid, Myzus persicae

(2013) Zhijie Jiang et al.   BMC GENOMICS

Horizontal Gene Transfer from Diverse Bacteria to an Insect Genome Enables a Tripartite Nested Mealybug Symbiosis

(2013) Filip Husnik et al.   CELL

Small, Smaller, Smallest: The Origins and Evolution of Ancient Dual Symbioses in a Phloem-Feeding Insect

(2013) Gordon M. Bennett et al.   Genome Biology and Evolution

Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Solutions to the Same Problem

(2013) Sylvia Hsu-Chen Yip et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome Reduction Promotes Increase in Protein Functional Complexity in Bacteria

(2012) Y. D. Kelkar et al.   GENETICS

EcoGene 3.0

(2012) Jindan Zhou et al.   NUCLEIC ACIDS RESEARCH

BRENDA in 2013: integrated reactions, kinetic data, enzyme function data, improved disease classification: new options and contents in BRENDA

(2012) Ida Schomburg et al.   NUCLEIC ACIDS RESEARCH

Network Context and Selection in the Evolution to Enzyme Specificity

(2012) H. Nam et al.   SCIENCE

Genomic revelations of a mutualism: the pea aphid and its obligate bacterial symbiont

(2011) Shuji Shigenobu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional Plasticity and Allosteric Regulation of α-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism

(2011) Tristan Wagner et al.   CHEMISTRY & BIOLOGY

An Interdependent Metabolic Patchwork in the Nested Symbiosis of Mealybugs

(2011) John P. McCutcheon et al.   CURRENT BIOLOGY

Origins of Specificity and Promiscuity in Metabolic Networks

(2011) Pablo Carbonell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome Expansion and Differential Expression of Amino Acid Transporters at the Aphid/Buchnera Symbiotic Interface

(2011) D. R. G. Price et al.   MOLECULAR BIOLOGY AND EVOLUTION

KEGG for integration and interpretation of large-scale molecular data sets

(2011) M. Kanehisa et al.   NUCLEIC ACIDS RESEARCH

A Genomic Reappraisal of Symbiotic Function in the Aphid/Buchnera Symbiosis: Reduced Transporter Sets and Variable Membrane Organisations

(2011) Hubert Charles et al.   PLoS One

Aphid genome expression reveals host-symbiont cooperation in the production of amino acids

(2011) A. K. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence Conservation and Functional Constraint on Intergenic Spacers in Reduced Genomes of the Obligate Symbiont Buchnera

(2011) Patrick H. Degnan et al.   PLoS Genetics

Serratia symbiotica from the Aphid Cinara cedri: A Missing Link from Facultative to Obligate Insect Endosymbiont

(2011) Araceli Lamelas et al.   PLoS Genetics

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

The bacterial essence of tiny symbiont genomes

(2010) John P McCutcheon   CURRENT OPINION IN MICROBIOLOGY

Genomic insight into the amino acid relations of the pea aphid, Acyrthosiphon pisum, with its symbiotic bacterium Buchnera aphidicola

(2010) A. C. C. Wilson et al.   INSECT MOLECULAR BIOLOGY

Genome Sequence of the Pea Aphid Acyrthosiphon pisum

(2010)   PLOS BIOLOGY

An examination of aspartate decarboxylase and glutamate decarboxylase activity in mosquitoes

(2009) Graham Richardson et al.   MOLECULAR BIOLOGY REPORTS

Origin of an Alternative Genetic Code in the Extremely Small and GC–Rich Genome of a Bacterial Symbiont

(2009) John P. McCutcheon et al.   PLoS Genetics