Escherichia colid-Malate Dehydrogenase, a Generalist Enzyme Active in the Leucine Biosynthesis Pathway

Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Solutions to the Same Problem

(2013) Sylvia Hsu-Chen Yip et al.   MOLECULAR BIOLOGY AND EVOLUTION

Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase

(2012) Susana Gonçalves et al.   BIOCHEMISTRY

Enzyme functional evolution through improved catalysis of ancestrally nonpreferred substrates

(2012) R. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Network Context and Selection in the Evolution to Enzyme Specificity

(2012) H. Nam et al.   SCIENCE

Reconstruction of Ancestral Metabolic Enzymes Reveals Molecular Mechanisms Underlying Evolutionary Innovation through Gene Duplication

(2012) Karin Voordeckers et al.   PLOS BIOLOGY

The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters

(2011) Arren Bar-Even et al.   BIOCHEMISTRY

ProtTest 3: fast selection of best-fit models of protein evolution

(2011) Diego Darriba et al.   BIOINFORMATICS

Toward a Systems Biology Perspective on Enzyme Evolution

(2011) Shelley D. Copley   JOURNAL OF BIOLOGICAL CHEMISTRY

Atomic level description of the domain closure in a dimeric enzyme: Thermus thermophilus 3-isopropylmalate dehydrogenase

(2011) Éva Gráczer et al.   Molecular BioSystems

Structural characterization of tartrate dehydrogenase: a versatile enzyme catalyzing multiple reactions

(2010) Radhika Malik et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

Regulation of Aerobic and Anaerobic D-Malate Metabolism of Escherichia coli by the LysR-Type Regulator DmlR (YeaT)

(2010) H. Lukas et al.   JOURNAL OF BACTERIOLOGY

Messy biology and the origins of evolutionary innovations

(2010) Dan S Tawfik   Nature Chemical Biology

Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli

(2010) V. W. C. Soo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An efficient, multiply promiscuous hydrolase in the alkaline phosphatase superfamily

(2010) B. van Loo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determinants of performance in the isocitrate dehydrogenase of Escherichia coli

(2010) Antony M. Dean et al.   PROTEIN SCIENCE

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Potassium Is an Activator of Homoisocitrate Dehydrogenase fromSaccharomyces cerevisiae†

(2008) Ying Lin et al.   BIOCHEMISTRY

Phylogeny.fr: robust phylogenetic analysis for the non-specialist

(2008) A. Dereeper et al.   NUCLEIC ACIDS RESEARCH

A compromise required by gene sharing enables survival: Implications for evolution of new enzyme activities

(2008) S. Y. McLoughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA