Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars

Experimental Strategies for Functional Annotation and Metabolism Discovery: Targeted Screening of Solute Binding Proteins and Unbiased Panning of Metabolomes

(2015) Matthew W. Vetting et al.   BIOCHEMISTRY

Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks

(2015) John A. Gerlt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Transcriptional Regulation by the Short-Chain Fatty Acyl Coenzyme A Regulator (ScfR) PccR Controls Propionyl Coenzyme A Assimilation by Rhodobacter sphaeroides

(2015) Michael S. Carter et al.   JOURNAL OF BACTERIOLOGY

ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel d-Altritol and Galactitol Catabolic Pathways inAgrobacterium tumefaciensC58

(2015) Daniel J. Wichelecki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis

(2015) Hua Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein Domains of Unknown Function Are Essential in Bacteria

(2014) N. F. Goodacre et al.   mBio

The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold

(2014) Hua Zhang et al.   Nature Communications

Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system

(2014) Weiwei Wang et al.   eLife

Revealing the hidden functional diversity of an enzyme family

(2013) Karine Bastard et al.   Nature Chemical Biology

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

3-Keto-5-aminohexanoate Cleavage Enzyme

(2011) Marco Bellinzoni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Domain of Unknown Function 3233 is a Translocation Domain of Autotransporter Secretory Mechanism in Gamma proteobacteria

(2011) Ananth Prakash et al.   PLoS One

DUFs: families in search of function

(2010) Alex Bateman et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Targeting effectors: the molecular recognition of Type III secreted proteins

(2010) Roland Arnold et al.   MICROBES AND INFECTION

Gluconate Metabolism Is Required for Virulence of the Soft-Rot PathogenPectobacterium carotovorum

(2010) Beth Mole et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

From complete genome sequence to ‘complete’ understanding?

(2010) Michael Y. Galperin et al.   TRENDS IN BIOTECHNOLOGY

Automatic policing of biochemical annotations using genomic correlations

(2009) Tzu-Lin Hsiao et al.   Nature Chemical Biology

Annotation Error in Public Databases: Misannotation of Molecular Function in Enzyme Superfamilies

(2009) Alexandra M. Schnoes et al.   PLoS Computational Biology

A genome level survey of Burkholderia pseudomallei immunome expressed during human infection

(2008) Yu-Ching Su et al.   MICROBES AND INFECTION