X chromosome inactivation in human development

En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements

(2019) Hyeon J Lee et al.   NUCLEIC ACIDS RESEARCH

Epigenetic aberrations in human pluripotent stem cells

(2019) Shiran Bar et al.   EMBO JOURNAL

Single‐cell RNA‐seq reveals distinct dynamic behavior of sex chromosomes during early human embryogenesis

(2019) Qing Zhou et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Global Characterization of X Chromosome Inactivation in Human Pluripotent Stem Cells

(2019) Shiran Bar et al.   Cell Reports

Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation

(2019) Irene Talon et al.   Frontiers in Cell and Developmental Biology

Identifying Human Naïve Pluripotent Stem Cells − Evaluating State-Specific Reporter Lines and Cell-Surface Markers

(2018) Amanda J. Collier et al.   BIOESSAYS

The Ftx Noncoding Locus Controls X Chromosome Inactivation Independently of Its RNA Products

(2018) Giulia Furlan et al.   MOLECULAR CELL

Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells

(2018) Ábel Vértesy et al.   Nature Communications

The Implication of Early Chromatin Changes in X Chromosome Inactivation

(2018) Jan Jakub Żylicz et al.   CELL

Genomic imprinting ofXistby maternal H3K27me3

(2017) Azusa Inoue et al.   GENES & DEVELOPMENT

Regulation of X-chromosome dosage compensation in human: mechanisms and model systems

(2017) Anna Sahakyan et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

When the Lyon(ized chromosome) roars: ongoing expression from an inactive X chromosome

(2017) Laura Carrel et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation

(2017) Sanjeet Patel et al.   Cell Reports

Early X chromosome inactivation during human preimplantation development revealed by single-cell RNA-sequencing

(2017) Joana C. Moreira de Mello et al.   Scientific Reports

Allele-Specific Methylome and Transcriptome Analysis Reveals Widespread Imprinting in the Human Placenta

(2016) Hirotaka Hamada et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Establishment of X chromosome inactivation and epigenomic features of the inactive X depend on cellular contexts

(2016) Céline Vallot et al.   BIOESSAYS

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

(2016) Sophie Petropoulos et al.   CELL

Molecular Criteria for Defining the Naive Human Pluripotent State

(2016) Thorold W. Theunissen et al.   Cell Stem Cell

Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification

(2016) Ferdinand von Meyenn et al.   DEVELOPMENTAL CELL

Self-organization of the in vitro attached human embryo

(2016) Alessia Deglincerti et al.   NATURE

Self-organization of the human embryo in the absence of maternal tissues

(2016) Marta N. Shahbazi et al.   NATURE CELL BIOLOGY

D-repeat in theXISTgene is required for X chromosome inactivation

(2016) Qingyan Lv et al.   RNA Biology

RNA binding proteins implicated in Xist-mediated chromosome silencing

(2016) Benoit Moindrot et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Function and evolution of the long noncoding RNA circuitry orchestrating X-chromosome inactivation in mammals

(2016) Giulia Furlan et al.   Wiley Interdisciplinary Reviews-RNA

The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells

(2015) Fan Guo et al.   CELL

Systematic Discovery of Xist RNA Binding Proteins

(2015) Ci Chu et al.   CELL

DNA Demethylation Dynamics in the Human Prenatal Germline

(2015) Sofia Gkountela et al.   CELL

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

(2015) Walfred W.C. Tang et al.   CELL

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

(2015) Naoko Irie et al.   CELL

Erosion of X Chromosome Inactivation in Human Pluripotent Cells Initiates with XACT Coating and Depends on a Specific Heterochromatin Landscape

(2015) Céline Vallot et al.   Cell Stem Cell

The pluripotent state in mouse and human

(2015) K. C. Davidson et al.   DEVELOPMENT

Is there a relationship between time-lapse parameters and embryo sex?

(2015) Fernando Bronet et al.   FERTILITY AND STERILITY

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer

(2015) Ronan Chaligné et al.   GENOME RESEARCH

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

(2015) Colleen A. McHugh et al.   NATURE

A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

(2015) A. Minajigi et al.   SCIENCE

Single-Cell XIST Expression in Human Preimplantation Embryos and Newly Reprogrammed Female Induced Pluripotent Stem Cells

(2015) Sharon F. Briggs et al.   STEM CELLS

A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

(2015) Benoit Moindrot et al.   Cell Reports

Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells

(2015) Asun Monfort et al.   Cell Reports

Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome

(2015) Norishige Yamada et al.   PLoS Genetics

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

(2014) Yasuhiro Takashima et al.   CELL

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators

(2014) Daniel W. Bellott et al.   NATURE

Comparison of gender-specific human embryo development characteristics by time-lapse technology

(2014) Munevver Serdarogullari et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Neuropsychology and brain morphology in Klinefelter syndrome - the impact of genetics

(2014) A. Skakkebaek et al.   Andrology

Jpx RNA Activates Xist by Evicting CTCF

(2013) Sha Sun et al.   CELL

Different flavors of X-chromosome inactivation in mammals

(2013) Cathérine Dupont et al.   CURRENT OPINION IN CELL BIOLOGY

Translating dosage compensation to trisomy 21

(2013) Jun Jiang et al.   NATURE

XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells

(2013) Céline Vallot et al.   NATURE GENETICS

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway

(2013) Ryu-Suke Nozawa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives

(2012) Kristopher L. Nazor et al.   Cell Stem Cell

Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling

(2012) Shila Mekhoubad et al.   Cell Stem Cell

Spatial partitioning of the regulatory landscape of the X-inactivation centre

(2012) Elphège P. Nora et al.   NATURE

Human aneuploidy: mechanisms and new insights into an age-old problem

(2012) So I. Nagaoka et al.   NATURE REVIEWS GENETICS

Cell Lineage Specific Distribution of H3K27 Trimethylation Accumulation in an In Vitro Model for Human Implantation

(2012) Gijs Teklenburg et al.   PLoS One

X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells

(2011) Bernhard Payer et al.   HUMAN GENETICS

The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting

(2011) et al.   HUMAN REPRODUCTION

Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development

(2011) Ikuhiro Okamoto et al.   NATURE

Regulation of X-chromosome inactivation by the X-inactivation centre

(2011) Sandrine Augui et al.   NATURE REVIEWS GENETICS

Female Sex Bias in Human Embryonic Stem Cell Lines

(2011) Dalit Ben-Yosef et al.   STEM CELLS AND DEVELOPMENT

Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations

(2010) Christopher J. Lengner et al.   CELL

The Long Noncoding RNA, Jpx, Is a Molecular Switch for X Chromosome Inactivation

(2010) Di Tian et al.   CELL

The Matrix Protein hnRNP U Is Required for Chromosomal Localization of Xist RNA

(2010) Yuko Hasegawa et al.   DEVELOPMENTAL CELL

The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender

(2010) Samer Alfarawati et al.   FERTILITY AND STERILITY

Association between amino acid turnover and chromosome aneuploidy during human preimplantation embryo development in vitro

(2010) H. M. Picton et al.   MOLECULAR HUMAN REPRODUCTION

Novel genetic aspects of Klinefelter's syndrome

(2010) F. Tuttelmann et al.   MOLECULAR HUMAN REPRODUCTION

Random X Inactivation and Extensive Mosaicism in Human Placenta Revealed by Analysis of Allele-Specific Gene Expression along the X Chromosome

(2010) Joana Carvalho Moreira de Mello et al.   PLoS One

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Blastocyst transfer and gender: IVF versus ICSI

(2009) Martha Agnes Hentemann et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Live birth sex ratios are not influenced by blastocyst-stage embryo transfer

(2008) John M. Csokmay et al.   FERTILITY AND STERILITY

Impact of blastocyst transfer on offspring sex ratio and the monozygotic twinning rate: a systematic review and meta-analysis

(2008) Hye Jin Chang et al.   FERTILITY AND STERILITY

X Chromosome Activity in Mouse XX Primordial Germ Cells

(2008) Susana M. Chuva de Sousa Lopes et al.   PLoS Genetics

X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells

(2008) S. S. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations

(2008) Y. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA