Translating dosage compensation to trisomy 21

Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives

(2012) Kristopher L. Nazor et al.   Cell Stem Cell

Trisomy Correction in Down Syndrome Induced Pluripotent Stem Cells

(2012) Li B. Li et al.   Cell Stem Cell

A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome

(2012) Y. Shi et al.   Science Translational Medicine

Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation

(2011) Allison M. Cotton et al.   HUMAN GENETICS

Gene Therapy Grows into Young Adulthood: Special Review Issue

(2011) B. Lee et al.   HUMAN MOLECULAR GENETICS

Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells

(2011) Jeffrey B. Doyon et al.   NATURE CELL BIOLOGY

Trisomy 21 and early brain development

(2011) Tarik F. Haydar et al.   TRENDS IN NEUROSCIENCES

Widespread Proliferation Impairment and Hypocellularity in the Cerebellum of Fetuses with Down Syndrome

(2010) Sandra Guidi et al.   BRAIN PATHOLOGY

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

(2010) R. C. DeKelver et al.   GENOME RESEARCH

Genome editing with engineered zinc finger nucleases

(2010) Fyodor D. Urnov et al.   NATURE REVIEWS GENETICS

Human Embryonic Stem Cells as Models for Aneuploid Chromosomal Syndromes

(2010) Juan-Carlos Biancotti et al.   STEM CELLS

The 50th anniversary of the discovery of trisomy 21: The past, present, and future of research and treatment of Down syndrome

(2009) André Mégarbané et al.   GENETICS IN MEDICINE

Molecular basis of pharmacotherapies for cognition in Down syndrome

(2009) Katheleen J. Gardiner   TRENDS IN PHARMACOLOGICAL SCIENCES

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected

(2008) Lisa L. Hall et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Derivation of Euploid Human Embryonic Stem Cells from Aneuploid Embryos

(2008) Neta Lavon et al.   STEM CELLS