Cardioprotective effect of ghrelin against myocardial infarction-induced left ventricular injury via inhibition of SOCS3 and activation of JAK2/STAT3 signaling

Ghrelin protects the heart against ischemia/reperfusion injury via inhibition of TLR4/NLRP3 inflammasome pathway

(2017) Qin Wang et al.   LIFE SCIENCES

Inhibition of mammalian target of rapamycin protects against reperfusion injury in diabetic heart through STAT3 signaling

(2015) Anindita Das et al.   BASIC RESEARCH IN CARDIOLOGY

Activation of mitochondrial STAT-3 and reduced mitochondria damage during hypothermia treatment for post-cardiac arrest myocardial dysfunction

(2015) Chien-Hua Huang et al.   BASIC RESEARCH IN CARDIOLOGY

Correlation between apoptosis and left ventricular remodeling in subacute phase of myocardial ischemia and reperfusion

(2015) Hiroshi Wakabayashi et al.   EJNMMI Research

Mechanisms of Ghrelin Anti-Heart Failure: Inhibition of Ang II-Induced Cardiomyocyte Apoptosis by Down-Regulating AT1R Expression

(2014) Chunyan Yang et al.   PLoS One

Desacyl ghrelin prevents doxorubicin-induced myocardial fibrosis and apoptosis via the GHSR-independent pathway

(2013) Xiao M. Pei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pharmacologic Therapy That Simulates Conditioning for Cardiac Ischemic/Reperfusion Injury

(2013) Vivek Sivaraman et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Multiple signaling pathways mediate ghrelin-induced proliferation of hippocampal neural stem cells

(2013) Hyunju Chung et al.   JOURNAL OF ENDOCRINOLOGY

SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway

(2012) Antonio Cittadini et al.   CARDIOVASCULAR RESEARCH

Growth Hormone Secretagogues Protect Mouse Cardiomyocytes from in vitro Ischemia/Reperfusion Injury through Regulation of Intracellular Calcium

(2012) Yi Ma et al.   PLoS One

STAT3α interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart

(2011) Sarah Pedretti et al.   BASIC RESEARCH IN CARDIOLOGY

Mitochondrial STAT3 Activation and Cardioprotection by Ischemic Postconditioning in Pigs With Regional Myocardial Ischemia/Reperfusion

(2011) Gerd Heusch et al.   CIRCULATION RESEARCH

STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy

(2011) J. McCormick et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cytoprotection by the modulation of mitochondrial electron transport chain: The emerging role of mitochondrial STAT3

(2011) Karol Szczepanek et al.   MITOCHONDRION

Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore

(2010) Christopher C. T. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

(2010) Kerstin Boengler et al.   BASIC RESEARCH IN CARDIOLOGY

Autophagy Facilitates IFN-γ-induced Jak2-STAT1 Activation and Cellular Inflammation

(2010) Yu-Ping Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel pharmacotherapies to abrogate postinfarction ventricular remodeling

(2009) Gerald W. Dorn   Nature Reviews Cardiology

Function of Mitochondrial Stat3 in Cellular Respiration

(2009) J. Wegrzyn et al.   SCIENCE

Granulocyte Colony-Stimulating Factor Prevents Reperfusion Injury After Heart Preservation

(2008) Takuya Higuchi et al.   ANNALS OF THORACIC SURGERY

Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion

(2008) Britt N. Fuglesteg et al.   BASIC RESEARCH IN CARDIOLOGY

IL-10 Inhibits Inflammation and Attenuates Left Ventricular Remodeling After Myocardial Infarction via Activation of STAT3 and Suppression of HuR

(2008) Prasanna Krishnamurthy et al.   CIRCULATION RESEARCH

The myocardial JAK/STAT pathway: From protection to failure

(2008) K BOENGLER et al.   PHARMACOLOGY & THERAPEUTICS

SOCS regulation of the JAK/STAT signalling pathway

(2008) Ben A. Croker et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ghrelin suppresses cardiac sympathetic activity and prevents early left ventricular remodeling in rats with myocardial infarction

(2007) Takeshi Soeki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY