Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation

Andrographolide decreased VEGFD expression in hepatoma cancer cells by inducing ubiquitin/proteasome-mediated cFos protein degradation

(2015) Lili Ji et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

NFAT1 deficit and NFAT2 deficit attenuate EAE via different mechanisms

(2015) Lena Dietz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The p38 mitogen-activated protein kinase cascade modulates T helper type 17 differentiation and functionality in multiple sclerosis

(2015) Diletta Di Mitri et al.   IMMUNOLOGY

Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression

(2015) Muhammad S Alam et al.   NATURE MEDICINE

Counter-regulation of T cell effector function by differentially activated p38

(2014) Muhammad S. Alam et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation

(2011) L. Jirmanova et al.   BLOOD

A Role for the Immediate Early Gene Product c-fos in Imprinting T Cells with Short-Term Memory for Signal Summation

(2011) Carolyn E. Clark et al.   PLoS One

NFAT pulls the strings during CD4+ T helper cell effector functions

(2010) N. Hermann-Kleiter et al.   BLOOD

T Cell Receptor-mediated Activation of p38α by Mono-phosphorylation of the Activation Loop Results in Altered Substrate Specificity

(2009) Paul R. Mittelstadt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY