DAMPs, MAMPs, and NAMPs in plant innate immunity

Newly Identified Targets of Aspirin and Its Primary Metabolite, Salicylic Acid

(2016) Daniel F. Klessig   DNA AND CELL BIOLOGY

HMGB1 as biomarker and drug target

(2016) Emilie Venereau et al.   PHARMACOLOGICAL RESEARCH

Activation of Plant Innate Immunity by Extracellular High Mobility Group Box 3 and Its Inhibition by Salicylic Acid

(2016) Hyong Woo Choi et al.   PLoS Pathogens

Multiple Targets of Salicylic Acid and Its Derivatives in Plants and Animals

(2016) Daniel F. Klessig et al.   Frontiers in Immunology

Danger peptide receptor signaling in plants ensures basal immunity upon pathogen-induced depletion of BAK1

(2015) K. Yamada et al.   EMBO JOURNAL

MD-2 is required for disulfide HMGB1–dependent TLR4 signaling

(2015) Huan Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Salicylic Acid Inhibits the Replication ofTomato bushy stunt virusby Directly Targeting a Host Component in the Replication Complex

(2015) Miaoying Tian et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Serum 14-3-3η level is associated with severity and clinical outcomes of rheumatoid arthritis, and its pretreatment level is predictive of DAS28 remission with tocilizumab

(2015) Shintaro Hirata et al.   ARTHRITIS RESEARCH & THERAPY

Conserved nematode signalling molecules elicit plant defenses and pathogen resistance

(2015) Patricia Manosalva et al.   Nature Communications

Human GAPDH Is a Target of Aspirin’s Primary Metabolite Salicylic Acid and Its Derivatives

(2015) Hyong Woo Choi et al.   PLoS One

Extracellular ADP prevents neuronal apoptosis via activation of cell antioxidant enzymes and protection of mitochondrial ANT-1

(2014) A. Bobba et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Extracellular UDP-Glucose Activates P2Y14Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705Phosphorylation and Binding to Hyaluronan Synthase 2 (HAS2) Promoter, Stimulating Hyaluronan Synthesis of Keratinocytes

(2014) Tiina A. Jokela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines

(2014) Y. Sha et al.   JOURNAL OF IMMUNOLOGY

Extracellular UDP and P2Y6Function as a Danger Signal To Protect Mice from Vesicular Stomatitis Virus Infection through an Increase in IFN-β Production

(2014) Ruimei Li et al.   JOURNAL OF IMMUNOLOGY

Serum 14-3-3  is a Novel Marker that Complements Current Serological Measurements to Enhance Detection of Patients with Rheumatoid Arthritis

(2014) W. P. Maksymowych et al.   JOURNAL OF RHEUMATOLOGY

Plant PRRs and the Activation of Innate Immune Signaling

(2014) Alberto P. Macho et al.   MOLECULAR CELL

Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal

(2014) S. Salzano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Plant Receptor for Extracellular ATP

(2014) J. Choi et al.   SCIENCE

Plant pattern-recognition receptors

(2014) Cyril Zipfel   TRENDS IN IMMUNOLOGY

14-3-3η is a novel mediator associated with the pathogenesis of rheumatoid arthritis and joint damage

(2014) Walter P Maksymowych et al.   ARTHRITIS RESEARCH & THERAPY

HMGB1–LPS complex promotes transformation of osteoarthritis synovial fibroblasts to a rheumatoid arthritis synovial fibroblast-like phenotype

(2014) Y Qin et al.   Cell Death & Disease

DAMP Molecule S100A9 Acts as a Molecular Pattern to Enhance Inflammation during Influenza A Virus Infection: Role of DDX21-TRIF-TLR4-MyD88 Pathway

(2014) Su-Yu Tsai et al.   PLoS Pathogens

Extracellular ATP acts as a damage-associated molecular pattern (DAMP) signal in plants

(2014) Kiwamu Tanaka et al.   Frontiers in Plant Science

Danger signalling during cancer cell death: origins, plasticity and regulation

(2013) A D Garg et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

(2013) Shankar S. Iyer et al.   IMMUNITY

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Plant elicitor peptides are conserved signals regulating direct and indirect antiherbivore defense

(2013) A. Huffaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of purinergic signalling, the initial resistance and current explosion of interest

(2012) G Burnstock   BRITISH JOURNAL OF PHARMACOLOGY

PAMPs and DAMPs: signal 0s that spur autophagy and immunity

(2012) Daolin Tang et al.   IMMUNOLOGICAL REVIEWS

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

(2012) Milena Schiraldi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

(2012) Emilie Venereau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

(2012) Shigeki Chiba et al.   NATURE IMMUNOLOGY

HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

(2012) Helena Erlandsson Harris et al.   Nature Reviews Rheumatology

Transcriptional reprogramming by root knot and migratory nematode infection in rice

(2012) Tina Kyndt et al.   NEW PHYTOLOGIST

Evolution of jasmonate and salicylate signal crosstalk

(2012) Jennifer S. Thaler et al.   TRENDS IN PLANT SCIENCE

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

(2011) Yury I. Miller et al.   CIRCULATION RESEARCH

Endogenous peptide elicitors in higher plants

(2011) Yube Yamaguchi et al.   CURRENT OPINION IN PLANT BIOLOGY

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Hyaluronan as an Immune Regulator in Human Diseases

(2011) Dianhua Jiang et al.   PHYSIOLOGICAL REVIEWS

TheArabidopsisLeucine-Rich Repeat Receptor–Like Kinases BAK1/SERK3 and BKK1/SERK4 Are Required for Innate Immunity to Hemibiotrophic and Biotrophic Pathogens

(2011) Milena Roux et al.   PLANT CELL

ZmPep1, an Ortholog of Arabidopsis Elicitor Peptide 1, Regulates Maize Innate Immunity and Enhances Disease Resistance

(2011) A. Huffaker et al.   PLANT PHYSIOLOGY

Substantial Histone Reduction Modulates Genomewide Nucleosomal Occupancy and Global Transcriptional Output

(2011) Barbara Celona et al.   PLOS BIOLOGY

The role of chromosomal HMGB proteins in plants

(2010) Dorthe S. Pedersen et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Extracellular ATP and P2Y Receptor Activation Induce a Proinflammatory Host Response in the Human Urinary Tract

(2010) S. Save et al.   INFECTION AND IMMUNITY

Oxidized Phospholipids Are More Potent Antagonists of Lipopolysaccharide than Inducers of Inflammation

(2010) O. V. Oskolkova et al.   JOURNAL OF IMMUNOLOGY

Tail-Mediated Collapse of HMGB1 Is Dynamic and Occurs via Differential Binding of the Acidic Tail to the A and B Domains

(2010) Katherine Stott et al.   JOURNAL OF MOLECULAR BIOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

PEPR2 Is a Second Receptor for the Pep1 and Pep2 Peptides and Contributes to Defense Responses in Arabidopsis

(2010) Y. Yamaguchi et al.   PLANT CELL

Jasmonate and ppHsystemin Regulate Key Malonylation Steps in the Biosynthesis of 17-Hydroxygeranyllinalool Diterpene Glycosides, an Abundant and Effective Direct Defense against Herbivores in Nicotiana attenuata

(2010) S. Heiling et al.   PLANT CELL

A domain swap approach reveals a role of the plant wall-associated kinase 1 (WAK1) as a receptor of oligogalacturonides

(2010) A. Brutus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Salicylic Acid, a Multifaceted Hormone to Combat Disease

(2009) A. Corina Vlot et al.   Annual Review of Phytopathology

A Renaissance of Elicitors: Perception of Microbe-Associated Molecular Patterns and Danger Signals by Pattern-Recognition Receptors

(2009) Thomas Boller et al.   Annual Review of Plant Biology

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

(2009) Theocharis Panaretakis et al.   EMBO JOURNAL

Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

(2009) Andrea Babelova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGB1 Enhances the Proinflammatory Activity of Lipopolysaccharide by Promoting the Phosphorylation of MAPK p38 through Receptor for Advanced Glycation End Products

(2009) Y.-H. Qin et al.   JOURNAL OF IMMUNOLOGY

Heat shock proteins and immune system

(2009) Min-Fu Tsan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

(2009) Hideyuki Yanai et al.   NATURE

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family

(2009) R. D. Ye et al.   PHARMACOLOGICAL REVIEWS

Isolation and Characterization of Hydroxyproline-Rich Glycopeptide Signals in Black Nightshade Leaves

(2009) G. Pearce et al.   PLANT PHYSIOLOGY

CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses

(2009) G.-Y. Chen et al.   SCIENCE

One for all: the receptor-associated kinase BAK1

(2009) Delphine Chinchilla et al.   TRENDS IN PLANT SCIENCE

Pattern recognition receptors in the immune response against dying cells

(2008) Pascale Jeannin et al.   CURRENT OPINION IN IMMUNOLOGY

Six Peptide Wound Signals Derived from a Single Precursor Protein inIpomoea batatasLeaves Activate the Expression of the Defense Gene Sporamin

(2008) Yu-Chi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidized Phospholipid Inhibition of Toll-like Receptor (TLR) Signaling Is Restricted to TLR2 and TLR4

(2008) Clett Erridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of Defense Response Pathways by OGs and Flg22 Elicitors in Arabidopsis Seedlings

(2008) Carine Denoux et al.   Molecular Plant