Molecular regulation of autophagy machinery by mTOR‐dependent and ‐independent pathways
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Title
Molecular regulation of autophagy machinery by mTOR‐dependent and ‐independent pathways
Authors
Keywords
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Journal
Annals of the New York Academy of Sciences
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-01-27
DOI
10.1111/nyas.14305
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Note: Only part of the references are listed.- Modulated Autophagy by MicroRNAs in Osteoarthritis Chondrocytes
- (2019) Yinghao Yu et al. Biomed Research International
- The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance
- (2019) Valentina Tedeschi et al. Scientific Reports
- TRPML1: The Ca (2+) retaker of the lysosome
- (2018) Simone Di Paola et al. CELL CALCIUM
- TRPs and Ca 2+ in cell death and survival
- (2018) Ingrid Fliniaux et al. CELL CALCIUM
- The regulation of autophagy by calcium signals: Do we have a consensus?
- (2018) Martin D. Bootman et al. CELL CALCIUM
- A ravenous defense: canonical and non-canonical autophagy in immunity
- (2018) Payel Sil et al. CURRENT OPINION IN IMMUNOLOGY
- Sorting out “non‐canonical” autophagy
- (2018) Dorotea Fracchiolla et al. EMBO JOURNAL
- The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization
- (2018) Peng Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)
- (2018) Yann Cormerais et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms
- (2018) Chinwendu Nwadike et al. MOLECULAR AND CELLULAR BIOLOGY
- Hitchhiking on selective autophagy
- (2018) Christian Münch et al. NATURE CELL BIOLOGY
- The coming of age of chaperone-mediated autophagy
- (2018) Susmita Kaushik et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanism and medical implications of mammalian autophagy
- (2018) Ivan Dikic et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions
- (2018) Yufei Song et al. Scientific Reports
- IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice
- (2018) Denisse Valladares et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death
- (2018) Paula Szalai et al. CELL CALCIUM
- Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency
- (2018) Guilhian Leipnitz et al. Scientific Reports
- AMPK contributes to autophagosome maturation and lysosomal fusion
- (2018) Minsu Jang et al. Scientific Reports
- MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress
- (2018) Deniz Gulfem Ozturk et al. Autophagy
- mTORC1 as the main gateway to autophagy
- (2017) Yoana Rabanal-Ruiz et al. Essays in Biochemistry
- AMP-activated protein kinase–mediated feedback phosphorylation controls the Ca2+/calmodulin (CaM) dependence of Ca2+/CaM-dependent protein kinase kinase β
- (2017) Akihiro Nakanishi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+depletion and the unfolded protein response
- (2017) Pankaj Sehgal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia inducible factor-1α regulates autophagy via the p27-E2F1 signaling pathway
- (2017) Pan Wang et al. Molecular Medicine Reports
- Erratum: Autophagy: controlling cell fate in rheumatic diseases
- (2017) Jason S. Rockel et al. Nature Reviews Rheumatology
- Twenty-five years of mTOR: Uncovering the link from nutrients to growth
- (2017) David M. Sabatini PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway
- (2017) Xin Gu et al. SCIENCE
- Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1
- (2017) Tianlong Zhang et al. Nature Communications
- Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
- (2017) Rhianna C. Laker et al. Nature Communications
- PML nuclear bodies contribute to the basal expression of the mTOR inhibitor DDIT4
- (2017) Jayme Salsman et al. Scientific Reports
- XBP1-FoxO1 interaction regulates ER stress-induced autophagy in auditory cells
- (2017) Akihiro Kishino et al. Scientific Reports
- Mechanism of arginine sensing by CASTOR1 upstream of mTORC1
- (2016) Robert A. Saxton et al. NATURE
- A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation
- (2016) Xinran Li et al. NATURE CELL BIOLOGY
- Autophagy in acute brain injury
- (2016) Lorenzo Galluzzi et al. NATURE REVIEWS NEUROSCIENCE
- Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes
- (2016) Anna Raffaello et al. TRENDS IN BIOCHEMICAL SCIENCES
- Autophagy regulates resistance of non-small cell lung cancer cells to paclitaxel
- (2016) Kan Chen et al. TUMOR BIOLOGY
- Mediation of Autophagic Cell Death by Type 3 Ryanodine Receptor (RyR3) in Adult Hippocampal Neural Stem Cells
- (2016) Kyung Min Chung et al. Frontiers in Cellular Neuroscience
- MCOLN1 is a ROS sensor in lysosomes that regulates autophagy
- (2016) Xiaoli Zhang et al. Nature Communications
- Regulation of mTORC1 by lysosomal calcium and calmodulin
- (2016) Ruo-Jing Li et al. eLife
- Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
- (2016) Bernadette Carroll et al. eLife
- Conserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signaling
- (2016) Katie Powis et al. Cell Discovery
- MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals
- (2015) Jia Yuan et al. Autophagy
- Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy
- (2015) Jun He et al. Autophagy
- The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase
- (2015) R. U. Onyenwoke et al. BIOCHEMICAL JOURNAL
- Autophagy: A housekeeper in cardiorenal metabolic health and disease
- (2015) Guanghong Jia et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms
- (2015) Lulu Li et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
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- (2015) C. Raiborg et al. EMBO JOURNAL
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- Autophagy: a druggable process that is deregulated in aging and human disease
- (2015) Guido Kroemer JOURNAL OF CLINICAL INVESTIGATION
- SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
- (2015) Manuele Rebsamen et al. NATURE
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- (2015) Diego L. Medina et al. NATURE CELL BIOLOGY
- Autophagy at the crossroads of catabolism and anabolism
- (2015) Jasvinder Kaur et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The mucolipin-2 (TRPML2) ion channel: a tissue-specific protein crucial to normal cell function
- (2015) Math P. Cuajungco et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
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- (2015) Murali Prakriya et al. PHYSIOLOGICAL REVIEWS
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- (2015) Wuyang Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2015) S. Wang et al. SCIENCE
- Sestrin2 is a leucine sensor for the mTORC1 pathway
- (2015) R. L. Wolfson et al. SCIENCE
- Differential regulation of mTORC1 by leucine and glutamine
- (2015) J. L. Jewell et al. SCIENCE
- UPR, autophagy, and mitochondria crosstalk underlies the ER stress response
- (2015) Daniela Senft et al. TRENDS IN BIOCHEMICAL SCIENCES
- Regulation of mTORC1 by PI3K signaling
- (2015) Christian C. Dibble et al. TRENDS IN CELL BIOLOGY
- LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation
- (2015) Ruth Milkereit et al. Nature Communications
- miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG
- (2015) Longtao Huangfu et al. Oncotarget
- A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation
- (2015) Guang Yang et al. Cell Reports
- MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin
- (2015) Zhiyu Wang et al. Oncotarget
- Oxidative stress and autophagy: the clash between damage and metabolic needs
- (2014) G Filomeni et al. CELL DEATH AND DIFFERENTIATION
- A Redox-Dependent Mechanism for Regulation of AMPK Activation by Thioredoxin1 during Energy Starvation
- (2014) Dan Shao et al. Cell Metabolism
- Hypoxia-induced autophagy reduces radiosensitivity by the HIF-1α/miR-210/Bcl-2 pathway in colon cancer cells
- (2014) YONG SUN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Ral and Rheb GTPase Activating Proteins Integrate mTOR and GTPase Signaling in Aging, Autophagy, and Tumor Cell Invasion
- (2014) Timothy D. Martin et al. MOLECULAR CELL
- The axis of MAPK1/3-XBP1u-FOXO1 controls autophagic dynamics in cancer cells
- (2013) Ying Zhao et al. Autophagy
- Ca2+in quality control
- (2013) Daniel A East et al. Autophagy
- Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway
- (2013) Gang Wan et al. Autophagy
- The Ca2+ channel TRPML3 specifically interacts with the mammalian ATG8 homologue GATE16 to regulate autophagy
- (2013) Suzy Choi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Loss of TRPML1 promotes production of reactive oxygen species: is oxidative damage a factor in mucolipidosis type IV?
- (2013) Jessica Coblentz et al. BIOCHEMICAL JOURNAL
- Nutrients and growth factors in mTORC1 activation
- (2013) Alejo Efeyan et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The PH Domain of Phosphoinositide-Dependent Kinase-1 Exhibits a Novel, Phospho-Regulated Monomer–Dimer Equilibrium with Important Implications for Kinase Domain Activation: Single-Molecule and Ensemble Studies
- (2013) Brian P. Ziemba et al. BIOCHEMISTRY
- ER stress-induced cell death mechanisms
- (2013) Renata Sano et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases
- (2013) Constance S. Petit et al. JOURNAL OF CELL BIOLOGY
- TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
- (2013) Carmine Settembre et al. NATURE CELL BIOLOGY
- Signals from the lysosome: a control centre for cellular clearance and energy metabolism
- (2013) Carmine Settembre et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
- (2013) Wafa B’chir et al. NUCLEIC ACIDS RESEARCH
- A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1
- (2013) L. Bar-Peled et al. SCIENCE
- MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
- (2012) Jose A. Martina et al. Autophagy
- miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1
- (2012) Gozde Korkmaz et al. Autophagy
- Drosophila TRPML Is Required for TORC1 Activation
- (2012) Ching-On Wong et al. CURRENT BIOLOGY
- XBP1mRNA Splicing Triggers an Autophagic Response in Endothelial Cells throughBECLIN-1Transcriptional Activation
- (2012) Andriana Margariti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphoinositide isoforms determine compartment-specific ion channel activity
- (2012) X. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The miR-290-295 cluster suppresses autophagic cell death of melanoma cells
- (2012) Yong Chen et al. Scientific Reports
- Ins(1,4,5)P3receptor-mediated Ca2+signaling and autophagy induction are interrelated
- (2011) Jean-Paul Decuypere et al. Autophagy
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- A dual role for Ca2+ in autophagy regulation
- (2011) Jean-Paul Decuypere et al. CELL CALCIUM
- LAPTMs regulate lysosomal function and interact with mucolipin 1: new clues for understanding mucolipidosis type IV
- (2011) S. Vergarajauregui et al. JOURNAL OF CELL SCIENCE
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- Canonical and non-canonical autophagy: variations on a common theme of self-eating?
- (2011) Patrice Codogno et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling
- (2011) P. P. Hsu et al. SCIENCE
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo
- (2011) R Russo et al. Cell Death & Disease
- The IP3 receptor–mitochondria connection in apoptosis and autophagy
- (2010) Jean-Paul Decuypere et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning
- (2010) Gregg L. Semenza BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
- (2010) Yasemin Sancak et al. CELL
- Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
- (2010) Simon A. Hawley et al. Cell Metabolism
- FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor
- (2010) Chia-Chen Chen et al. DEVELOPMENTAL CELL
- mTORC1 Signaling under Hypoxic Conditions Is Controlled by ATM-Dependent Phosphorylation of HIF-1α
- (2010) Hakan Cam et al. MOLECULAR CELL
- Intronic miR-211 Assumes the Tumor Suppressive Function of Its Host Gene in Melanoma
- (2010) Carmit Levy et al. MOLECULAR CELL
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- The Regulation of miRNA-211 Expression and Its Role in Melanoma Cell Invasiveness
- (2010) Joseph Mazar et al. PLoS One
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- Regulation of autophagy by ROS: physiology and pathology
- (2010) Ruth Scherz-Shouval et al. TRENDS IN BIOCHEMICAL SCIENCES
- PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome
- (2010) Xian-ping Dong et al. Nature Communications
- Autophagy, Redox Signaling, and Ventricular Remodeling
- (2009) Narasimman Gurusamy et al. ANTIOXIDANTS & REDOX SIGNALING
- Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
- (2009) Paul Nicklin et al. CELL
- The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
- (2009) J M Vicencio et al. CELL DEATH AND DIFFERENTIATION
- TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells
- (2009) Griselda Herrero-Martín et al. EMBO JOURNAL
- Identification of the Penta-EF-hand Protein ALG-2 as a Ca2+-dependent Interactor of Mucolipin-1
- (2009) Silvia Vergarajauregui et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chaperone-mediated autophagy is defective in mucolipidosis type IV
- (2009) Bhuvarahamurthy Venugopal et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
- (2009) Nao Hosokawa et al. MOLECULAR BIOLOGY OF THE CELL
- A Gene Network Regulating Lysosomal Biogenesis and Function
- (2009) Marco Sardiello et al. SCIENCE
- The Ca2+Channel TRPML3 Regulates Membrane Trafficking and Autophagy
- (2009) Hyun Jin Kim et al. TRAFFIC
- mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
- (2008) Juan M. García-Martínez et al. BIOCHEMICAL JOURNAL
- Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3 and BNIP3L
- (2008) I Papandreou et al. CELL DEATH AND DIFFERENTIATION
- Amino Acids Activate mTOR Complex 1 via Ca2+/CaM Signaling to hVps34
- (2008) Pawan Gulati et al. Cell Metabolism
- Extracellular matrix regulation of autophagy
- (2008) Rebecca Lock et al. CURRENT OPINION IN CELL BIOLOGY
- Functional Requirement for Orai1 in Store-operated TRPC1-STIM1 Channels
- (2008) Kwong Tai Cheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
- (2008) Dana M. Gwinn et al. MOLECULAR CELL
- Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
- (2008) Andrea Williams et al. Nature Chemical Biology
- Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
- (2008) Inki Kim et al. NATURE REVIEWS DRUG DISCOVERY
- The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
- (2008) Y. Sancak et al. SCIENCE
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