NHC-Stabilized Iridium Nanoparticles as Catalysts in Hydrogen Isotope Exchange Reactions of Anilines
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
NHC-Stabilized Iridium Nanoparticles as Catalysts in Hydrogen Isotope Exchange Reactions of Anilines
Authors
Keywords
-
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 59, Issue 9, Pages 3517-3522
Publisher
Wiley
Online
2019-12-18
DOI
10.1002/anie.201914369
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Directed Iridium‐Catalyzed Hydrogen Isotope Exchange Reactions of Phenylacetic Acid Esters and Amides
- (2019) Mégane Valero et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly Selective Directed Iridium-Catalyzed Hydrogen Isotope Exchange Reactions of Aliphatic Amides
- (2018) Mégane Valero et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences
- (2018) Jens Atzrodt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Palladium(II)-Mediated C−H Tritiation of Complex Pharmaceuticals
- (2018) Haifeng Yang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- C−H Functionalisation for Hydrogen Isotope Exchange
- (2018) Jens Atzrodt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Ruthenium-catalyzed hydrogen isotope exchange of C(sp3)–H bonds directed by a sulfur atom
- (2018) Longhui Gao et al. CHEMICAL COMMUNICATIONS
- Evaluation of a P,N-ligated iridium(I) catalyst in hydrogen isotope exchange reactions of aryl and heteroaryl compounds
- (2018) Mégane Valero et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- Iridium-Catalyzed Csp3–H Activation for Mild and Selective Hydrogen Isotope Exchange
- (2018) William J. Kerr et al. ACS Catalysis
- Hydrogen-Isotope Exchange (HIE) Reactions of Secondary and Tertiary Sulfonamides and Sulfonylureas with Iridium(I) Catalysts
- (2017) Annina Burhop et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Burgess iridium(I)-catalyst for selective hydrogen isotope exchange
- (2017) Annina Burhop et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds
- (2017) Yong Yao Loh et al. SCIENCE
- Cobalt-Catalyzed Stereoretentive Hydrogen Isotope Exchange of C(sp3)–H Bonds
- (2017) W. Neil Palmer et al. ACS Catalysis
- Modular Bidentate Hybrid NHC-Thioether Ligands for the Stabilization of Palladium Nanoparticles in Various Solvents
- (2016) Andreas Rühling et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Iridium-catalysed ortho-H/D and -H/T exchange under basic conditions: C–H activation of unprotected tetrazoles
- (2016) William J. Kerr et al. CHEMICAL COMMUNICATIONS
- Deuterium medicinal chemistry comes of age
- (2016) Roger D Tung Future Medicinal Chemistry
- Stereoretentive Deuteration of α-Chiral Amines with D2O
- (2016) Lillian V. A. Hale et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Iron-catalysed tritiation of pharmaceuticals
- (2016) Renyuan Pony Yu et al. NATURE
- Ballbot-type motion of N-heterocyclic carbenes on gold surfaces
- (2016) Gaoqiang Wang et al. Nature Chemistry
- Rapid Protium–Deuterium Exchange of 4-Aminopyridines in Neutral D2O under Microwave Irradiation
- (2016) Mark Bagley et al. SYNLETT
- Enantiospecific CH Activation Using Ruthenium Nanocatalysts
- (2015) Céline Taglang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Isotope chemistry; a useful tool in the drug discovery arsenal
- (2015) Charles S. Elmore et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- New Route to Stabilize Ruthenium Nanoparticles with Non-Isolable Chiral N-Heterocyclic Carbenes
- (2015) Luis Miguel Martínez-Prieto et al. CHEMISTRY-A EUROPEAN JOURNAL
- Expanded applicability of iridium(I) NHC/phosphine catalysts in hydrogen isotope exchange processes with pharmaceutically-relevant heterocycles
- (2015) Jens Atzrodt et al. TETRAHEDRON
- Hydrogen–deuterium exchange of aromatic amines and amides using deuterated trifluoroacetic acid
- (2015) Richard Giles et al. TETRAHEDRON LETTERS
- The Synthesis of Highly Active Iridium(I) Complexes and their Application in Catalytic Hydrogen Isotope Exchange
- (2014) Jack A. Brown et al. ADVANCED SYNTHESIS & CATALYSIS
- Deuterated drugs: where are we now?
- (2014) Graham S Timmins EXPERT OPINION ON THERAPEUTIC PATENTS
- An overview of N-heterocyclic carbenes
- (2014) Matthew N. Hopkinson et al. NATURE
- Practically convenient and industrially-aligned methods for iridium-catalysed hydrogen isotope exchange processes
- (2014) A. R. Cochrane et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Bioanalysis for plasma protein binding studies in drug discovery and drug development: views and recommendations of the European Bioanalysis Forum
- (2014) Brigitte Buscher et al. Bioanalysis
- Regioselective and Stereospecific Deuteration of Bioactive Aza Compounds by the Use of Ruthenium Nanoparticles
- (2013) Grégory Pieters et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A perspective on tritium versus carbon-14: ensuring optimal label selection in pharmaceutical research and development
- (2013) Joel A. Krauser JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- Using Deuterium in Drug Discovery: Leaving the Label in the Drug
- (2013) Thomas G. Gant JOURNAL OF MEDICINAL CHEMISTRY
- Carbene Transfer from Triazolylidene Gold Complexes as a Potent Strategy for Inducing High Catalytic Activity
- (2013) Daniel Canseco-Gonzalez et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Copolymer-Incarcerated Nickel Nanoparticles with N-Heterocyclic Carbene Precursors as Active Cross-Linking Agents for Corriu–Kumada–Tamao Reaction
- (2013) Jean-François Soulé et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Addressable Carbene Anchors for Gold Surfaces
- (2013) Aleksandr V. Zhukhovitskiy et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Heavy drugs draw heavy interest from pharma backers
- (2013) Alla Katsnelson NATURE MEDICINE
- Use of Radioactive Compounds and Autoradiography to Determine Drug Tissue Distribution
- (2012) Eric G. Solon CHEMICAL RESEARCH IN TOXICOLOGY
- Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?
- (2012) Natalia Penner et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Use of Radiolabeled Compounds in Drug Metabolism and Pharmacokinetic Studies
- (2012) Emre M. Isin et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Tritium: a coming of age for drug discovery and development ADME studies
- (2012) W. J. S. Lockley et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- Ruthenium-Catalyzed Selective α,β-Deuteration of Bioactive Amines
- (2012) Lorenz Neubert et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Measuring substrate binding and affinity of purified membrane transport proteins using the scintillation proximity assay
- (2012) Daniel Harder et al. Nature Protocols
- Ruthenium Nanoparticles Stabilized by N-Heterocyclic Carbenes: Ligand Location and Influence on Reactivity
- (2011) Patricia Lara et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric Nanocatalysis: N-Heterocyclic Carbenes as Chiral Modifiers of Fe3O4/Pd nanoparticles
- (2010) Kalluri V. S. Ranganath et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Ligand binding assays at equilibrium: validation and interpretation
- (2010) Edward C. Hulme et al. BRITISH JOURNAL OF PHARMACOLOGY
- Hydrogen isotope labelling using iridium(I) dionates
- (2010) W. J. S. Lockley JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- The effect of adding Crabtree's catalyst to rhodium black in direct hydrogen isotope exchange reactions
- (2009) Søren Christian Schou JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- N-Heterocyclic carbene coated metal nanoparticles
- (2009) Eleanor C. Hurst et al. NEW JOURNAL OF CHEMISTRY
- Highly active iridium(i) complexes for catalytic hydrogen isotope exchange
- (2008) Jack A. Brown et al. CHEMICAL COMMUNICATIONS
- Application of Stable Isotope-Labeled Compounds in Metabolism and in Metabolism-Mediated Toxicity Studies
- (2008) Abdul E. Mutlib CHEMICAL RESEARCH IN TOXICOLOGY
- A Simple, Cost-Effective Method for the Regioselective Deuteration of Anilines
- (2008) Andrew Martins et al. ORGANIC LETTERS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started