Palladium(II)-Mediated C−H Tritiation of Complex Pharmaceuticals

Direct 11CN-Labeling of Unprotected Peptides via Palladium-Mediated Sequential Cross-Coupling Reactions

(2017) Wenjun Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-accelerated non-directed C–H functionalization of arenes

(2017) Peng Wang et al.   NATURE

Water-Soluble Palladium Reagents for Cysteine S-Arylation under Ambient Aqueous Conditions

(2017) Anthony J. Rojas et al.   ORGANIC LETTERS

Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds

(2017) Yong Yao Loh et al.   SCIENCE

Iron-catalysed tritiation of pharmaceuticals

(2016) Renyuan Pony Yu et al.   NATURE

Isotope chemistry; a useful tool in the drug discovery arsenal

(2015) Charles S. Elmore et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Virtually Instantaneous, Room-Temperature [11C]-Cyanation Using Biaryl Phosphine Pd(0) Complexes

(2015) Hong Geun Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organometallic palladium reagents for cysteine bioconjugation

(2015) Ekaterina V. Vinogradova et al.   NATURE

The Synthesis of Highly Active Iridium(I) Complexes and their Application in Catalytic Hydrogen Isotope Exchange

(2014) Jack A. Brown et al.   ADVANCED SYNTHESIS & CATALYSIS

CH Bond Arylation in the Synthesis of Aryltetralin Lignans: A Short Total Synthesis of Podophyllotoxin

(2014) Chi P. Ting et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzedortho-Selective CH Deuteration of Arenes: Evidence for Superior Reactivity of Weakly Coordinated Palladacycles

(2013) Sandy Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Application of Palladium-Mediated 18F-Fluorination to PET Radiotracer Development: Overcoming Hurdles to Translation

(2013) Adam S. Kamlet et al.   PLoS One

Use of Radiolabeled Compounds in Drug Metabolism and Pharmacokinetic Studies

(2012) Emre M. Isin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Tritium: a coming of age for drug discovery and development ADME studies

(2012) W. J. S. Lockley et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Efficient H-D Exchange Reactions Using Heterogeneous Platinum-Group Metal on Carbon-H2-D2O System

(2012) Hironao Sajiki et al.   SYNLETT

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

A Fluoride-Derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging

(2011) E. Lee et al.   SCIENCE

Ligand binding assays at equilibrium: validation and interpretation

(2010) Edward C. Hulme et al.   BRITISH JOURNAL OF PHARMACOLOGY

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Overview of the Mechanistic Work on the Concerted Metallation–Deprotonation Pathway

(2010) David Lapointe et al.   CHEMISTRY LETTERS

Metal-catalysed hydrogen isotope exchange labelling: a brief overview

(2010) William J. S. Lockley et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

The development and use of iridium(I) phosphine systems for ortho-directed hydrogen-isotope exchange

(2010) Rhys Salter   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

The development and use of novel iridium complexes as catalysts for ortho-directed hydrogen isotope exchange reactions

(2010) Göran N. Nilsson et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Palladium-CatalyzedOrtho-Arylation ofO-Phenylcarbamates with Simple Arenes and Sodium Persulfate

(2010) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2and sp3Carbon−Hydrogen Bonds

(2010) Dmitry Shabashov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-catalyzed ortho-arylation of phenylacetamides, benzamides, and anilides with simple arenes using sodium persulfate

(2010) Charles S. Yeung et al.   Chemical Science