IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening

Review of Current Strategies for Delivering Alzheimer’s Disease Drugs across the Blood-Brain Barrier

(2019) Ka Wong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Culturing conditions highly affect DNA methylation and gene expression levels in MCF7 breast cancer cell line

(2018) Lama Hamadneh et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Contributions of the glycocalyx, endothelium, and extravascular compartment to the blood–brain barrier

(2018) Nikolay Kutuzov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Length of surface PEG modulates nanocarrier transcytosis across brain vascular endothelial cells

(2018) Soudeh F. Tehrani et al.   Nanomedicine-Nanotechnology Biology and Medicine

Dual role of ALCAM in neuroinflammation and blood–brain barrier homeostasis

(2017) Marc-André Lécuyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents

(2017) Choi-Fong Cho et al.   Nature Communications

Pericytes from Mesenchymal Stem Cells as a model for the blood-brain barrier

(2017) Xiaohe Tian et al.   Scientific Reports

Using cultured endothelial cells to study endothelial barrier dysfunction: Challenges and opportunities

(2016) Jurjan Aman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Immortalized endothelial cell lines for in vitro blood–brain barrier models: A systematic review

(2016) Nurul Adhwa Rahman et al.   BRAIN RESEARCH

ABC transporters at the blood–brain barrier

(2016) Anne Mahringer et al.   Expert Opinion on Drug Metabolism & Toxicology

Into rather unexplored terrain-transcellular transport across the blood-brain barrier

(2016) Marijke De Bock et al.   GLIA

A new PAMPA model using an in-house brain lipid extract for screening the blood–brain barrier permeability of drug candidates

(2016) Joana Bicker et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

(2016) Hans C Helms et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier

(2016) Maj Schneider Thomsen et al.   JOURNAL OF NEUROCHEMISTRY

Brain–blood ratio: implications in brain drug delivery

(2015) Abhijeet D Kulkarni et al.   Expert Opinion on Drug Delivery

CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure

(2015) Zoran Rankovic   JOURNAL OF MEDICINAL CHEMISTRY

In Vitro Blood–Brain Barrier Models—An Overview of Established Models and New Microfluidic Approaches

(2015) Anette Wolff et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Development and use of in vitro alternatives to animal testing by the pharmaceutical industry 1980–2013

(2015) Jen-Yin Goh et al.   Toxicology Research

In vitro porcine blood–brain barrier model for permeability studies: pCEL-X software pKaFLUX method for aqueous boundary layer correction and detailed data analysis

(2014) Siti R. Yusof et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Blood–brain barrier models: in vitro to in vivo translation in preclinical development of CNS-targeting biotherapeutics

(2014) Danica B Stanimirovic et al.   Expert Opinion on Drug Discovery

In Vitro Cerebrovascular Modeling in the 21st Century: Current and Prospective Technologies

(2014) Christopher A. Palmiotti et al.   PHARMACEUTICAL RESEARCH

Study of Blood and Brain Lithium Pharmacokinetics in the Rat According to Three Different Modalities of Poisoning

(2014) Anne-Sophie Hanak et al.   TOXICOLOGICAL SCIENCES

Isolation of Primary Murine Brain Microvascular Endothelial Cells

(2014) Tobias Ruck et al.   Jove-Journal of Visualized Experiments

Paracellular Barrier and Tight Junction Protein Expression in the Immortalized Brain Endothelial Cell Lines bEND.3, bEND.5 and Mouse Brain Endothelial Cell 4

(2013) Takuya Watanabe et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Blood–brain barrier structure and function and the challenges for CNS drug delivery

(2013) N. Joan Abbott   JOURNAL OF INHERITED METABOLIC DISEASE

Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood–brain barrier penetration models

(2012) Éva Hellinger et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Efflux transporters in the blood–brain interfaces –in vitroandin vivomethods and correlations

(2012) Péter Krajcsi et al.   Expert Opinion on Drug Metabolism & Toxicology

Membrane configuration optimization for a murine in vitro blood–brain barrier model

(2012) Diane M. Wuest et al.   JOURNAL OF NEUROSCIENCE METHODS

Optimization of endothelial cell growth in a murine in vitro blood-brain barrier model

(2011) Diane M. Wuest et al.   Biotechnology Journal

Drug-permeability and transporter assays in Caco-2 and MDCK cell lines

(2011) Donna A Volpe   Future Medicinal Chemistry

Effect of Surface Charge of Immortalized Mouse Cerebral Endothelial Cell Monolayer on Transport of Charged Solutes

(2010) Wei Yuan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Prediction of passive blood–brain partitioning: Straightforward and effective classification models based on in silico derived physicochemical descriptors

(2010) Santiago Vilar et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

(2008) Shinsuke Nakagawa et al.   NEUROCHEMISTRY INTERNATIONAL