ABC transporters at the blood–brain barrier

Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans

(2016) F. Anthony Willyerd et al.   JOURNAL OF NEUROTRAUMA

P-glycoprotein in autoimmune rheumatic diseases

(2015) M. García-Carrasco et al.   AUTOIMMUNITY REVIEWS

Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells

(2015) Eva Bernhart et al.   BIOCHEMICAL PHARMACOLOGY

Regulation of ABC transporters at the blood-brain barrier

(2015) DS Miller   CLINICAL PHARMACOLOGY & THERAPEUTICS

Isolation and characterization of cancer stem cells from medulloblastoma

(2015) J. Liu et al.   GENETICS AND MOLECULAR RESEARCH

Identification of P-glycoprotein co-fractionating proteins and specific binding partners in rat brain microvessels

(2015) Margaret E. Tome et al.   JOURNAL OF NEUROCHEMISTRY

Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2)

(2015) Anita Kort et al.   PHARMACOLOGICAL RESEARCH

Inhibition of multidrug resistance protein 1 (MRP1) improves chemotherapy drug response in primary and recurrent glioblastoma multiforme

(2015) Amanda Tivnan et al.   Frontiers in Neuroscience

P-glycoprotein regulates trafficking of CD8+ T cells to the brain parenchyma

(2014) Gijs Kooij et al.   ACTA NEUROPATHOLOGICA

Screening for impact of popular herbs improving mental abilities on the transcriptional level of brain transporters

(2014) Przemyslaw M. Mrozikiewicz et al.   ACTA PHARMACEUTICA

Expression of ATP-binding cassette membrane transporters in a HIV-1 transgenic rat model

(2014) Kevin R. Robillard et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Association between MDR1 C3435T polymorphism and refractory epilepsy in the Chinese population: A systematic review and meta-analysis

(2014) Ji-Wei Cheng et al.   EPILEPSY & BEHAVIOR

Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance

(2014) Oliver Bruhn et al.   Expert Opinion on Drug Metabolism & Toxicology

ABC transporters as differentiation markers in glioblastoma cells

(2014) Ana R. Rama et al.   MOLECULAR BIOLOGY REPORTS

P-Glycoprotein Mediated Efflux Limits the Transport of the Novel Anti-Parkinson's Disease Candidate Drug FLZ across the Physiological and PD Pathological In Vitro BBB Models

(2014) Qian Liu et al.   PLoS One

St. John's Wort Reduces Beta-Amyloid Accumulation in a Double Transgenic Alzheimer's Disease Mouse Model-Role of P-Glycoprotein

(2013) Anja Brenn et al.   BRAIN PATHOLOGY

Why Clinical Modulation of Efflux Transport at the Human Blood–Brain Barrier Is Unlikely: The ITC Evidence-Based Position

(2013) J C Kalvass et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Differential Phospholipid Substrates and Directional Transport by ATP-binding Cassette Proteins ABCA1, ABCA7, and ABCA4 and Disease-causing Mutants

(2013) Faraz Quazi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reductions in neuronal peroxisomes in multiple sclerosis grey matter

(2013) Elizabeth Gray et al.   Multiple Sclerosis Journal

P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387

(2013) S. Durmus et al.   PHARMACOLOGICAL RESEARCH

Cholesterol efflux is differentially regulated in neurons and astrocytes: Implications for brain cholesterol homeostasis

(2012) Jing Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The Clinical Impact of ABCB1 Polymorphisms on the Treatment of Psychiatric Diseases

(2012) Marcus C. Rosenhagen et al.   CURRENT PHARMACEUTICAL DESIGN

P-glycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia

(2012) Gwen McCaffrey et al.   JOURNAL OF NEUROCHEMISTRY

Selective increase of two ABC drug efflux transporters at the blood–spinal cord barrier suggests induced pharmacoresistance in ALS

(2012) Michael R. Jablonski et al.   NEUROBIOLOGY OF DISEASE

Tissue-specific alterations in expression and function of P-glycoprotein in streptozotocin-induced diabetic rats

(2011) Lu-lu Zhang et al.   ACTA PHARMACOLOGICA SINICA

Role of CNS efflux drug transporters in antiepileptic drug delivery: Overcoming CNS efflux drug transport

(2011) Heidrun Potschka   ADVANCED DRUG DELIVERY REVIEWS

The Neurovascular Link in Health and Disease: Molecular Mechanisms and Therapeutic Implications

(2011) Annelies Quaegebeur et al.   NEURON

Relationship between P-glycoprotein and second-generation antipsychotics

(2011) Tim Moons et al.   PHARMACOGENOMICS

P-glycoprotein and breast cancer resistance protein expression and function at the blood–brain barrier and blood–cerebrospinal fluid barrier (choroid plexus) in streptozotocin-induced diabetes in rats

(2010) Valeska Reichel et al.   BRAIN RESEARCH

Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier

(2010) Xueqian Wang et al.   FASEB JOURNAL

Direct and Coordinate Regulation of ATP-binding Cassette Transporter Genes by Myc Factors Generates Specific Transcription Signatures That Significantly Affect the Chemoresistance Phenotype of Cancer Cells

(2010) Antonio Porro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constitutive Androstane Receptor-Mediated Up-Regulation of ATP-Driven Xenobiotic Efflux Transporters at the Blood-Brain Barrier

(2010) X. Wang et al.   MOLECULAR PHARMACOLOGY

P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis

(2010) Aline Milane et al.   NEUROSCIENCE LETTERS

Apolipoprotein E Controls ATP-Binding Cassette Transporters in the Ischemic Brain

(2010) A. ElAli et al.   Science Signaling

Blood-Brain Interfaces and Bilirubin-Induced Neurological Diseases

(2009) J. Ghersi-Egea et al.   CURRENT PHARMACEUTICAL DESIGN

P-gp Transporter and its Role in Neurodegenerative Diseases

(2009) Simona Rapposelli et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood-Brain Barrier for A 1-40 Peptides

(2009) H. Xiong et al.   JOURNAL OF NEUROSCIENCE

Change in P-glycoprotein and caveolin protein expression in brain striatum capillaries in New Zealand Obese mice with type 2 diabetes

(2009) Kuo-Chen Wu et al.   LIFE SCIENCES

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

ABC Transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) Expression in the Developing Human CNS

(2009) M. Daood et al.   NEUROPEDIATRICS

Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier

(2008) Vishal S. Narang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Insulin therapy restores impaired function and expression of P-glycoprotein in blood–brain barrier of experimental diabetes

(2008) Haiyan Liu et al.   BIOCHEMICAL PHARMACOLOGY

ABCC1: a gateway for pharmacological compounds to the ischaemic brain

(2008) Ertugrul Kilic et al.   BRAIN

Insulin regulates P-glycoprotein in rat brain microvessel endothelial cells via an insulin receptor-mediated PKC/NF-κB pathway but not a PI3K/Akt pathway

(2008) Haiyan Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces

(2008) Silvia Gazzin et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Glutamate is critically involved in seizure-induced overexpression of P-glycoprotein in the brain

(2008) Jens P. Bankstahl et al.   NEUROPHARMACOLOGY

Subcellular localization of transporters along the rat blood–brain barrier and blood–cerebral-spinal fluid barrier by in vivo biotinylation

(2008) L.M. Roberts et al.   NEUROSCIENCE

Seizure-Induced Up-Regulation of P-Glycoprotein at the Blood-Brain Barrier through Glutamate and Cyclooxygenase-2 Signaling

(2007) B. Bauer et al.   MOLECULAR PHARMACOLOGY