TRIM8 Blunts the Pro-proliferative Action of ΔNp63α in a p53 Wild-Type Background

Targeting Chemoresistant Tumors: Could TRIM Proteins-p53 Axis Be a Possible Answer?

(2019) Valletti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sumoylation and ubiquitylation crosstalk in the control of ΔNp63α protein stability

(2018) Michela Ranieri et al.   GENE

TRIM8 restores p53 tumour suppressor function by blunting N-MYC activity in chemo-resistant tumours

(2017) Francesca Mastropasqua et al.   Molecular Cancer

TRIM8 downregulation in glioma affects cell proliferation and it is associated with patients survival

(2015) Lucia Micale et al.   BMC CANCER

Y-box Binding Protein-1 Is Part of a Complex Molecular Network Linking ΔNp63α to the PI3K/akt Pathway in Cutaneous Squamous Cell Carcinoma

(2015) Annaelena Troiano et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Maintaining epithelial stemness with p63

(2015) Gerry Melino et al.   Science Signaling

Maintaining epithelial stemness with p63

(2015) Gerry Melino et al.   Science Signaling

TRIM8 anti-proliferative action against chemo-resistant renal cell carcinoma

(2015) Mariano Francesco Caratozzolo et al.   Oncotarget

Regulation of p63 Protein Stability via Ubiquitin-Proteasome Pathway

(2014) Chenghua Li et al.   Biomed Research International

FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma

(2013) Matthew R. Ramsey et al.   JOURNAL OF CLINICAL INVESTIGATION

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis

(2013) Rubeta N. Matin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

High expression of p63 is correlated to poor prognosis in squamous cell carcinoma of the tongue

(2013) Lotta Loljung et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

TRIM8 modulates p53 activity to dictate cell cycle arrest

(2012) Mariano Francesco Caratozzolo et al.   CELL CYCLE

p63 regulates cell proliferation and cell cycle progression-associated genes in stromal cells of giant cell tumor of the bone

(2012) CAROL PO YING LAU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15

(2012) Young Joo Jeon et al.   JOURNAL OF CLINICAL INVESTIGATION

HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage

(2011) C Lazzari et al.   ONCOGENE

Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation

(2010) Antonella Di Costanzo et al.   CELL CYCLE

MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation

(2010) F. Galli et al.   JOURNAL OF CELL SCIENCE

Overexpression of p63 is associated with radiation resistance and prognosis in oral squamous cell carcinoma

(2010) Maximilian Moergel et al.   ORAL ONCOLOGY

p73 and p63 Sustain Cellular Growth by Transcriptional Activation of Cell Cycle Progression Genes

(2009) K. Lefkimmiatis et al.   CANCER RESEARCH

Identification and functional characterization of two new transcriptional variants of the human p63 gene

(2009) Marina Mangiulli et al.   NUCLEIC ACIDS RESEARCH

WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis

(2008) Y Li et al.   CELL DEATH AND DIFFERENTIATION

Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects

(2008) N. Lo Iacono et al.   DEVELOPMENT